AT5G17290

Gene Details

Gene ID: AT5G17290
Gene Symbol: APG5, ATATG5, ATG5
Gene Name: AUTOPHAGY 5, AUTOPHAGY 5
Description: autophagy protein Apg5 family;(source:Araport11)
TAIR Accession: locus:2167195
Genome: Araport11_genome_release
Species: Arabidopsis thaliana

Functional Descriptions

PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

GO:0050832 — acts upstream of or within — defense response to fungus
GO:0006501 — involved in — C-terminal protein lipidation
GO:0006914 — acts upstream of or within — autophagy
GO:0005737 — located in — cytoplasm
GO:0044804 — involved in — nucleophagy
GO:0006995 — involved in — cellular response to nitrogen starvation
GO:0010150 — acts upstream of or within — leaf senescence
GO:0019776 — contributes to — Atg8-family ligase activity
GO:0000045 — involved in — autophagosome assembly
GO:0034045 — is active in — phagophore assembly site membrane
GO:0000422 — involved in — autophagy of mitochondrion
GO:0034274 — part of — Atg12-Atg5-Atg16 complex
GO:0042594 — acts upstream of or within — response to starvation

CS39993 — Under a short-day photoperiod (8h light/16h dark), the atg5-1 plants grew slower resulting in smaller plants, flowered later with reduced fecundity, and showed enhanced senescence of rosette leaves than wild type; hypersensitive to either nitrogen or carbon deprivation.
SAIL_129_B07 — early senescence; accumulation of high levels of reactive oxygen species.
atg5-1 — The T-DNA insertion prevents accumulation of the ATG5 mRNA in the mutants. Absence of 50-kD and a 40-kD proteins, which correspond to the sizes of the conjugate ATG12-ATG5 and the ATG5 proteins, respectively. Homozygous atg5-1 seedlings germinated and developed normally, and flowered and set seed at the same rate as wild-type plants under a long-day photoperiod (16h light/8h dark). Under a short-day photoperiod (8h light/16h dark), the atg5-1 plants grew slower resulting in smaller plants, flowered later than wild type with reduced fecundity, and showed enhanced senescence of rosette leaves. Hypersensitive to N-deficient growth conditions (mutants presented enhanced chlorosis of the cotyledons and reduced true leaf formation). Low recovery rates (20%) after restoration of N in the media, as compared to 100% recovery rates in wildtype. Hypersensitive to carbon starvation induced by darkness (plants become severely chlorotic and flaccid faster and protein loss was higher than in wild type). In C-starved plants the protein levels of ATG7 decreased and the ATG5 increased in the mutant, whereas the protein levels of ATG8 did not drop, but the ATG8 mRNA level increased, unlike in wild type.
lon2-2 atg5-5 — IBA responsiveness to lon2-2 restored
lon2-2 atg5-6 — IBA responsiveness to lon2-2 restored

Functional Keywords

Literature and News

Gene Resources

Sequences

cDNA Sequence

>AT5G17290.1
CGTACGCCTTATTAATACCACATAAAGACGCAAGAGAAGATGACGTCATACAGAAACAGCGTCGTTTTGAAAGCTGAGTTTTTTTTGTGAAGCGAGCGAGCGTGAGAAGGTGTGACGGGGAAGAGAATGGCGAAGGAAGCGGTCAAGTATGTATGGGAAGGAGCAATTCCTCTGCAGATTCATCTCCACAAATCCGACGTCGCTTCTCACCCTGCTCCTCCTCCTGCTCTTGTGTTAGCACCAAGAATAGGATATTTGCCTCTGTTGATTCCTCTTATAAAGCCTTATTTCAAGGATTCACTTCCTCCTGGTGAAGATTCAATTTGGTTTGATTACAAAGGATTTCCTCTAAAATGGTATATACCAACAGGTGTTCTTTTCGATCTCCTTTGTGCAGAACCCGAAAGACCATGGAATCTCACGATACACTTTAGAGGATATCCTTGCAACATACTGATACCATGTGAAGGAGAAGATTCTGTAAAATGGAACTTTGTTAATTCTTTGAAAGAGGCACAATATATCATCAATGGAAATTGCAAGAATGTTATGAACATGTCTCAGAGTGATCAAGAGGATCTATGGACCTCTGTCATGAACGGTGATCTTGATGCCTATACAAGATTATCACCCAAGCTTAAAATGGGAACAGTCGAAGATGAGTTTTCAAGGAAAACAAGTTTGTCATCTCCACAATCTCAACAAGTTGTGCCTGAGACGGAGGTGGCTGGACAAGTTAAGACAGCAAGAATTCCTGTTCGGTTGTATGTTCGAAGTCTAAATAAAGATTTCGAGAATCTTGAAGATGTACCGGAGATCGATACCTGGGATGACATCTCGTACCTTAATCGCCCTGTTGAGTTCCTCAAAGAAGAAGGGAAATGCTTTACGTTACGTGACGCCATTAAAAGTCTCCTCCCTGAGTTTATGGGAGACAGAGCGCAAACGAGTGGTGAAGAAAGAAGCATAGATGATACAGAAGAAGCAGATGGGTCGAGGGAGATGGGTGAAATCAAATTGGTAAGGATACAAGGGATAGAAATGAAGCTAGAGATACCGTTTTCGTGGGTGGTAAATAACTTGATGAACCCAGAATTCTATCTCCATATCTCTGTCCTTGTGAAAGCTCCTCAAAGGTGAAGTGTAAGGTTCTCTGCAGTTACAATCCATCTGTGAATTGAATCAAATTGCTTTCTCGTTCCATCTTACAAATCCGAAAGAATCAATGATTTGTTGTATACAGCTACTTCTTCTATTTCTGATAGAAGCAAGAACACAGAATACAGAAAAGAAAGTAGAAATATTTTGATTGACTCGTTAGCTCTTTTACATTTGTTACTTGACGGTTTCCTCTCTGAGCAAATTTGATTGAAATCAATTTATGGTCGATATAATAATCACTACTTTCTTCTATTCACAAGTAAATCAGCTCAAGTTCATAGAGAGATCCAAAATGTTGTTCAACAAAAGCACTGTATCATCAAATCGACAAAGACAAATGTTTAATTTCTCCATTAACAATGCGAGGAAAAATCAGTCAAATTGATTTAGTTTCTCCAGAAAGCTGCTTGTTGTAATCTTCGAGCTCATCGTAATAAACATCCCAAACGCATCGGACGCAACCGCTACCGCAACAATCGCCAGGCTCTGGTTTCTCTGGCGGTGGAGGAACCGAAACTCCCACCTCCTTCTTATCTTCTGTCTCCTTCTTGTTTGTCTCCTCCTTGGAAGCTTCTACAAGATTCTTGCTCTCGGTCGTCGCCATGGTCACCGGAGATTTGAGCTGTTGTTCTGGAGATACGGAAGTGATTGAATAATTGGAGAAAGATCGTTTGAGAGGGAGATGTCGCGTCAAACCAAATCTCATGCTCAAAAGCACATCGTGAAGGCTAGAACCCGGTGATGTAACGATCGAGATTCGAGGAAGAAGAGACACAACAACCATACGCACAGATCAAAAAGATTTGTTCTCTTCTTTTTTTTTCTATTTCCTTTTTTCGTGTCAGAATTGATTTCTTTATGACCTGTCATCCTATAGTTGGCAAAAAAAGCCGCCAATCATAAACGGCACGCATATTTATCTTCTAAACGTTAAAACGGCACGACATCTTTTTTGAACACAAGAACCAACAACTTCTTGATCTTCAGCTGCGCCATGATTTTGA

CDS Sequence

Protein Sequence