Gene Details:

• Gene ID: AT5G16710
• Gene Symbol: DHAR3
• Gene Name: dehydroascorbate reductase 1
• Description: dehydroascorbate reductase 1;(source:Araport11)
• TAIR Accession: locus:2149015
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G16710.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0140547  — acts upstream of or within — acquisition of seed longevity
• GO:0019852  — acts upstream of or within — L-ascorbic acid metabolic process
• GO:0033355  — involved in — ascorbate glutathione cycle
• GO:0004364  — enables — glutathione transferase activity
• GO:0009941  — located in — chloroplast envelope
• GO:0009507  — located in — chloroplast
• GO:0009570  — located in — chloroplast stroma
• GO:0045174  — enables — glutathione dehydrogenase (ascorbate) activity
• GO:0098869  — involved in — cellular oxidant detoxification
• GO:0098869  — acts upstream of or within — cellular oxidant detoxification
• GO:0009536  — located in — plastid

Germplasm Phenotype:

• dhar123  — Triple mutant dhar123 resembles dhar1-4. Similar seed longevity decrease.

Function-related keywords:

• root

Literature:

• Functional divergence in the glutathione transferase superfamily in plants. Identification of two classes with putative functions in redox homeostasis in Arabidopsis thaliana.   DOI:  10.1074/jbc.M202919200 ;  PMID:  12077129
• Molecular definition of the ascorbate-glutathione cycle in Arabidopsis mitochondria reveals dual targeting of antioxidant defenses in plants.   DOI:  10.1074/jbc.M307525200 ;  PMID:  12954611
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Proteomic analysis of glutathione S -transferases of Arabidopsis thaliana reveals differential salicylic acid-induced expression of the plant-specific phi and tau classes.   DOI:  10.1023/B:PLAN.0000028786.57439.b3 ;  PMID:  15159623
• Evidence for a direct link between glutathione biosynthesis and stress defense gene expression in Arabidopsis.   DOI:  10.1105/tpc.104.022608 ;  PMID:  15308753
• New targets of Arabidopsis thioredoxins revealed by proteomic analysis.   DOI:  10.1002/pmic.200400805 ;  PMID:  15352244
• Cytosolic dehydroascorbate reductase is important for ozone tolerance in Arabidopsis thaliana.   DOI:  10.1093/pcp/pci246 ;  PMID:  16361320
• Proteomic analysis and extensive protein identification from dry, germinating Arabidopsis seeds and young seedlings.   DOI:  10.5483/bmbrep.2005.38.6.650 ;  PMID:  16336779
• Islands of co-expressed neighbouring genes in Arabidopsis thaliana suggest higher-order chromosome domains.   DOI:  10.1111/j.1365-313X.2005.02619.x ;  PMID:  16412082
• Comparative proteomic approaches for the isolation of proteins interacting with thioredoxin.   DOI:  10.1002/pmic.200600443 ;  PMID:  17163439
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Analysis of essential Arabidopsis nuclear genes encoding plastid-targeted proteins.   DOI:  10.1371/journal.pone.0073291 ;  PMID:  24023856
• Proteome and metabolome profiling of cytokinin action in Arabidopsis identifying and up-regulation.   DOI:  10.1093/jxb/ert227 ;  PMID:  24064926
• Arabidopsis dehydroascorbate reductase 1 and 2 modulate redox states of ascorbate-glutathione cycle in the cytosol in response to photooxidative stress.   DOI:  10.1080/09168451.2016.1256759 ;  PMID:  27852156
• Cytosolic and Chloroplastic DHARs Cooperate in Oxidative Stress-Driven Activation of the Salicylic Acid Pathway.   DOI:  10.1104/pp.17.00317 ;  PMID:  28381499
• Dehydroascorbate Reductases and Glutathione Set a Threshold for High-Light-Induced Ascorbate Accumulation.   DOI:  10.1104/pp.19.01556 ;  PMID:  32205453
• Identification of novel seed longevity genes related to oxidative stress and seed coat by genome-wide association studies and reverse genetics.   DOI:  10.1111/pce.13822 ;  PMID:  32519347
• Elevating Ascorbate in Arabidopsis Stimulates the Production of Abscisic Acid, Phaseic Acid, and to a Lesser Extent Auxin (IAA) and Jasmonates, Resulting in Increased Expression of DHAR1 and Multiple Transcription Factors Associated with Abiotic Stress Tolerance.   DOI:  10.3390/ijms22136743 ;  PMID:  34201662
• H(2)O(2) response gene 1/2 are novel sensors or responders of H(2)O(2) and involve in maintaining embryonic root meristem activity in Arabidopsis thaliana.   DOI:  10.1016/j.plantsci.2021.110981 ;  PMID:  34315597
• Overexpression mutants reveal a role for a chloroplast MPD protein in regulation of reactive oxygen species during chilling in Arabidopsis.   DOI:  10.1093/jxb/erac029 ;  PMID:  35084440
• Chloroplast dehydroascorbate reductase and glutathione cooperatively determine the capacity for ascorbate accumulation under photooxidative stress conditions.   DOI:  10.1111/tpj.16117 ;  PMID:  36694959
• Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.   DOI:  10.1021/pr034025j ;  PMID:  12938931
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209
• Stress-induced protein S-glutathionylation in Arabidopsis.   DOI:  10.1104/pp.104.058917 ;  PMID:  16055689
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis.   DOI:  10.1104/pp.108.124545 ;  PMID:  18633119
• The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.   DOI:  10.1074/mcp.M500180-MCP200 ;  PMID:  16207701
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464

Sequences: