Gene Details:

• Gene ID: AT5G16620
• Gene Symbol: ATTIC40, PDE120, TIC40
• Gene Name: translocon at the inner envelope membrane of chloroplasts 40, pigment defective embryo 120, translocon at the inner envelope membrane of chloroplasts 40
• Description: hydroxyproline-rich glycoprotein family protein;(source:Araport11)
• TAIR Accession: locus:2174155
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G16620.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0031897  — part of — Tic complex
• GO:0045037  — acts upstream of or within — protein import into chloroplast stroma
• GO:0009941  — located in — chloroplast envelope
• GO:0009535  — located in — chloroplast thylakoid membrane
• GO:0005515  — enables — protein binding
• GO:0009658  — involved in — chloroplast organization
• GO:0009658  — acts upstream of or within — chloroplast organization
• GO:0009706  — is active in — chloroplast inner membrane
• GO:0009507  — located in — chloroplast
• GO:0045037  — involved in — protein import into chloroplast stroma
• GO:0009706  — located in — chloroplast inner membrane
• GO:0009536  — located in — plastid

Germplasm Phenotype:

• CS16059  — pigment defective embryo
• CS2107727  — suppressor of tic40
• CS2107728  — suppressor of tic40
• CS2107729  — suppressor of tic40
• CS2107730  — suppressor of tic40
• CS2107731  — suppressor of tic40
• CS2107732  — suppressor of tic40
• CS2107733  — suppressor of tic40

Function-related keywords:

• root

Literature:

• Arabidopsis genes encoding components of the chloroplastic protein import apparatus.   DOI:  10.1104/pp.125.4.1567 ;  PMID:  11299338
• New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy.   DOI:  10.1074/jbc.M406763200 ;  PMID:  15322131
• Targeting of nucleus-encoded proteins to chloroplasts in plants.   DOI:  10.1111/j.1469-8137.2008.02452.x ;  PMID:  19086173
• Arabidopsis Tic40 expression in tobacco chloroplasts results in massive proliferation of the inner envelope membrane and upregulation of associated proteins.   DOI:  10.1105/tpc.108.063172 ;  PMID:  19060109
• Stimulation of transit-peptide release and ATP hydrolysis by a cochaperone during protein import into chloroplasts.   DOI:  10.1083/jcb.200609172 ;  PMID:  17158958
• Tic40 is important for reinsertion of proteins from the chloroplast stroma into the inner membrane.   DOI:  10.1111/j.1365-313X.2008.03638.x ;  PMID:  18657235
• Stromal Hsp70 is important for protein translocation into pea and Arabidopsis chloroplasts.   DOI:  10.1105/tpc.109.071415 ;  PMID:  20484004
• Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis.   DOI:  10.1104/pp.110.168120 ;  PMID:  21139083
• Identification of imprinted genes subject to parent-of-origin specific expression in Arabidopsis thaliana seeds.   DOI:  10.1186/1471-2229-11-113 ;  PMID:  21838868
• An essential role for chloroplast heat shock protein 90 (Hsp90C) in protein import into chloroplasts.   DOI:  10.1073/pnas.1219229110 ;  PMID:  23382192
• The TIC complex uncovered: The alternative view on the molecular mechanism of protein translocation across the inner envelope membrane of chloroplasts.   DOI:  10.1016/j.bbabio.2015.02.011 ;  PMID:  25689609
• Identification of Putative Substrates of SEC2, a Chloroplast Inner Envelope Translocase.   DOI:  10.1104/pp.17.00012 ;  PMID:  28213560
• Suppressors of the Chloroplast Protein Import Mutant tic40 Reveal a Genetic Link between Protein Import and Thylakoid Biogenesis.   DOI:  10.1105/tpc.16.00962 ;  PMID:  28684427
• TIC236 links the outer and inner membrane translocons of the chloroplast.   DOI:  10.1038/s41586-018-0713-y ;  PMID:  30464337
• Photosynthesis in Arabidopsis Is Unaffected by the Function of the Vacuolar K(+) Channel TPK3.   DOI:  10.1104/pp.19.00255 ;  PMID:  31053658
• Arabidopsis ORANGE protein regulates plastid pre-protein import through interacting with Tic proteins.   DOI:  10.1093/jxb/eraa528 ;  PMID:  33165598
• Two plastid POLLUX ion channel-like proteins are required for stress-triggered stromal Ca2+release.   DOI:  10.1093/plphys/kiab424 ;  PMID:  34618095
• Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.   DOI:  10.1074/mcp.M300030-MCP200 ;  PMID:  12766230
• Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.   DOI:  10.1021/pr034025j ;  PMID:  12938931
• New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy.   DOI:  10.1074/jbc.M406763200 ;  PMID:  15322131
• In vivo studies on the roles of Tic110, Tic40 and Hsp93 during chloroplast protein import.   DOI:  10.1111/j.1365-313X.2004.02307.x ;  PMID:  15659100
• Reconstitution of protein targeting to the inner envelope membrane of chloroplasts.   DOI:  10.1083/jcb.200605162 ;  PMID:  17060496
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Functional similarity between the chloroplast translocon component, Tic40, and the human co-chaperone, Hsp70-interacting protein (Hip).   DOI:  10.1074/jbc.M611545200 ;  PMID:  17535810
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequences: