Gene Details:

• Gene ID: AT5G13300
• Gene Symbol: AGD3, FKD2, FKD2, SFC, VAN3
• Gene Name: ARF-GAP DOMAIN3, FORKED 2, SCARFACE, ASCULAR NETWORK DEFECTIVE 3
• Description: ARF GTPase-activating protein;(source:Araport11)
• TAIR Accession: locus:2183916
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G13300.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0009733  — acts upstream of or within — response to auxin
• GO:0010051  — acts upstream of or within — xylem and phloem pattern formation
• GO:0030140  — located in — trans-Golgi network transport vesicle
• GO:0005096  — enables — GTPase activator activity
• GO:0009965  — acts upstream of or within — leaf morphogenesis
• GO:0005634  — located in — nucleus
• GO:0010087  — acts upstream of or within — phloem or xylem histogenesis
• GO:0005886  — located in — plasma membrane
• GO:0035091  — enables — phosphatidylinositol binding
• GO:0005575  — is active in — cellular_component
• GO:0005515  — enables — protein binding
• GO:0006897  — acts upstream of or within — endocytosis

Germplasm Phenotype:

• van3-1  — Abnormal pattern of leaf veneation. Veins are discontinous in cotyledons although the overall architeture of venation is not affected.

Function-related keywords:

• root

Literature:

• The SCARFACE gene is required for cotyledon and leaf vein patterning.   DOI:  10.1242/dev.127.15.3205 ;  PMID:  10887077
• A series of novel mutants of Arabidopsis thaliana that are defective in the formation of continuous vascular network: calling the auxin signal flow canalization hypothesis into question.   DOI:  10.1242/dev.127.15.3197 ;  PMID:  10887076
• Analysis of the small GTPase gene superfamily of Arabidopsis.   DOI:  10.1104/pp.013052 ;  PMID:  12644670
• The ATE genes are responsible for repression of transdifferentiation into xylem cells in Arabidopsis.   DOI:  10.1104/pp.104.055145 ;  PMID:  15618413
• VAN3 ARF-GAP-mediated vesicle transport is involved in leaf vascular network formation.   DOI:  10.1242/dev.01716 ;  PMID:  15743878
• DRP1A is responsible for vascular continuity synergistically working with VAN3 in Arabidopsis.   DOI:  10.1104/pp.105.061689 ;  PMID:  15923323
• SCARFACE encodes an ARF-GAP that is required for normal auxin efflux and vein patterning in Arabidopsis.   DOI:  10.1105/tpc.105.039008 ;  PMID:  16698946
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157
• and CVL1-mediated phosphoinositide signaling as a regulator of the ARF GAP SFC/VAN3 in establishment of foliar vein patterns.   DOI:  10.1111/j.1365-313X.2009.03920.x ;  PMID:  19473324
• Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants.   DOI:  10.1242/dev.030098 ;  PMID:  19363154
• ADP-ribosylation factor machinery mediates endocytosis in plant cells.   DOI:  10.1073/pnas.1016260107 ;  PMID:  21118984
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion.   DOI:  10.1093/jxb/erx180 ;  PMID:  28575401
• ARF GTPase machinery at the plasma membrane regulates auxin transport-mediated plant growth.   DOI:  10.5511/plantbiotechnology.18.0312a ;  PMID:  31819717
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157

Sequences: