Gene Details:

• Gene ID: AT5G13160
• Gene Symbol: PBS1
• Gene Name: avrPphB susceptible 1
• Description: Protein kinase superfamily protein;(source:Araport11)
• TAIR Accession: locus:2179857
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G13160.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0046777  — acts upstream of or within — protein autophosphorylation
• GO:0042742  — acts upstream of or within — defense response to bacterium
• GO:0005515  — enables — protein binding
• GO:0004672  — enables — protein kinase activity
• GO:0005634  — located in — nucleus
• GO:0005886  — located in — plasma membrane
• GO:0004674  — enables — protein serine/threonine kinase activity
• GO:0042742  — involved in — defense response to bacterium
• GO:0006952  — acts upstream of or within — defense response
• GO:0045087  — involved in — innate immune response
• GO:0002221  — involved in — pattern recognition receptor signaling pathway

Germplasm Phenotype:

• CS3872  — susceptible to Pseudomonas syringae expressing avrPphB avirulence gene; completely blocks resistance mediated by the RPS5 gene; lacks hypersensitive response in HR assay as well as in transient expression assay; exhibits little to no effect on resistance specified by other disease resistance genes, facilitating recognition of the avrPphB protein; segregating for glabrous phenotype.
• CS3873  — susceptible to Pseudomonas syringae expressing avrPphB avirulence gene; completely blocks resistance mediated by the RPS5 gene; lacks hypersensitive response in HR assay as well as in transient expression assay; exhibits little to no effect on resistance specified by other disease resistance genes, facilitating recognition of the avrPphB protein.

Function-related keywords:

• root

Literature:

• Identification of three putative signal transduction genes involved in R gene-specified disease resistance in Arabidopsis.   DOI:  10.1093/genetics/152.1.401 ;  PMID:  10224270
• The Arabidopsis PBS1 resistance gene encodes a member of a novel protein kinase subfamily.   DOI:  10.1046/j.1365-313x.2001.01014.x ;  PMID:  11359614
• Indirect activation of a plant nucleotide binding site-leucine-rich repeat protein by a bacterial protease.   DOI:  10.1073/pnas.0608779104 ;  PMID:  17277084
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Arabidopsis thaliana genes encoding defense signaling and recognition proteins exhibit contrasting evolutionary dynamics.   DOI:  10.1534/genetics.108.097279 ;  PMID:  19064707
• Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by a Pseudomonas syringae effector.   DOI:  10.1016/j.chom.2010.03.007 ;  PMID:  20413097
• Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.   DOI:  10.1016/j.phytochem.2011.02.029 ;  PMID:  21477822
• N-terminal motifs in some plant disease resistance proteins function in membrane attachment and contribute to disease resistance.   DOI:  10.1094/MPMI-11-10-0272 ;  PMID:  22046960
• Activation of a plant nucleotide binding-leucine rich repeat disease resistance protein by a modified self protein.   DOI:  10.1111/j.1462-5822.2012.01779.x ;  PMID:  22372664
• Recognition of the protein kinase AVRPPHB SUSCEPTIBLE1 by the disease resistance protein RESISTANCE TO PSEUDOMONAS SYRINGAE5 is dependent on s-acylation and an exposed loop in AVRPPHB SUSCEPTIBLE1.   DOI:  10.1104/pp.113.227686 ;  PMID:  24225654
• Microbe-associated molecular pattern-induced calcium signaling requires the receptor-like cytoplasmic kinases, PBL1 and BIK1.   DOI:  10.1186/s12870-014-0374-4 ;  PMID:  25522736
• Using decoys to expand the recognition specificity of a plant disease resistance protein.   DOI:  10.1126/science.aad3436 ;  PMID:  26912853
• Comparative study of Arabidopsis PBS1 and a wheat PBS1 homolog helps understand the mechanism of PBS1 functioning in innate immunity.   DOI:  10.1038/s41598-017-05904-x ;  PMID:  28710392
• Roles of Receptor-Like Cytoplasmic Kinase VII Members in Pattern-Triggered Immune Signaling.   DOI:  10.1104/pp.18.00486 ;  PMID:  29907700
• Optimizing the PBS1 Decoy System to Confer Resistance to Potyvirus Infection in Arabidopsis and Soybean.   DOI:  10.1094/MPMI-07-19-0190-R ;  PMID:  32267815
• RPS5-Mediated Disease Resistance: Fundamental Insights and Translational Applications.   DOI:  10.1146/annurev-phyto-010820-012733 ;  PMID:  32284014
• The TIR-NBS protein TN13 associates with the CC-NBS-LRR resistance protein RPS5 and contributes to RPS5-triggered immunity in Arabidopsis.   DOI:  10.1111/tpj.15345 ;  PMID:  33982335
• The Arabidopsis MIK2 receptor elicits immunity by sensing a conserved signature from phytocytokines and microbes.   DOI:  10.1038/s41467-021-25580-w ;  PMID:  34535661
• Conservation of the PBL-RBOH immune module in land plants.   DOI:  10.1016/j.cub.2023.01.050 ;  PMID:  36796360
• Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote.   DOI:  10.1074/jbc.M307321200 ;  PMID:  12912986

Sequences: