Gene Details:

• Gene ID: AT5G13050
• Gene Symbol: 5-FCL
• Gene Name: 5-formyltetrahydrofolate cycloligase
• Description: 5-formyltetrahydrofolate cycloligase;(source:Araport11)
• TAIR Accession: locus:2179827
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G13050.1     AT5G13050.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0035999  — involved in — tetrahydrofolate interconversion
• GO:0005737  — located in — cytoplasm
• GO:0046653  — acts upstream of or within — tetrahydrofolate metabolic process
• GO:0030272  — enables — 5-formyltetrahydrofolate cyclo-ligase activity
• GO:0009396  — involved in — folic acid-containing compound biosynthetic process
• GO:0006952  — acts upstream of or within — defense response
• GO:0005739  — located in — mitochondrion
• GO:0005739  — is active in — mitochondrion

Germplasm Phenotype:

• SAIL_28_D07  — Visible differences between mutant plants and their wild type siblings were modest. The growth rate of mutant plants was 20% lower, and they showed a flowering delay of about 1 week. There was no difference in leaf color or form.

Function-related keywords:

• root

Literature:

• New connections across pathways and cellular processes: industrialized mutant screening reveals novel associations between diverse phenotypes in Arabidopsis.   DOI:  10.1104/pp.107.115220 ;  PMID:  18263779
• A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism.   DOI:  10.1007/s10142-011-0224-5 ;  PMID:  21538139
• Translational Regulation of Metabolic Dynamics during Effector-Triggered Immunity.   DOI:  10.1016/j.molp.2019.09.009 ;  PMID:  31568832

Sequences: