Gene Details:

• Gene ID: AT5G10480
• Gene Symbol: PAS2, PEP, PEPINO
• Gene Name: PASTICCINO 2, PEPINO,
• Description: Protein-tyrosine phosphatase-like, PTPLA;(source:Araport11)
• TAIR Accession: locus:2142429
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G10480.1     AT5G10480.2     AT5G10480.3

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0030148  — involved in — sphingolipid biosynthetic process
• GO:0042761  — involved in — very long-chain fatty acid biosynthetic process
• GO:0030154  — acts upstream of or within — cell differentiation
• GO:0005515  — enables — protein binding
• GO:0009923  — part of — fatty acid elongase complex
• GO:0042761  — acts upstream of or within — very long-chain fatty acid biosynthetic process
• GO:0005739  — located in — mitochondrion
• GO:0048640  — acts upstream of or within — negative regulation of developmental growth
• GO:0030497  — involved in — fatty acid elongation
• GO:0005829  — located in — cytosol
• GO:0005634  — located in — nucleus
• GO:0004725  — enables — protein tyrosine phosphatase activity
• GO:0050732  — acts upstream of or within — negative regulation of peptidyl-tyrosine phosphorylation
• GO:0018812  — enables — 3-hydroxyacyl-CoA dehydratase activity
• GO:0005783  — located in — endoplasmic reticulum
• GO:0051302  — acts upstream of or within — regulation of cell division

Germplasm Phenotype:

• CS73026  — severe developmental defects
• CS73222  — abnormal cell division beginning at embryo stage; seedling root shows moderate growth retardation; recessive lethal mutant that cannot survive on soil
• pas2-3  — Segregates 25% embryo lethal.

Function-related keywords:

• root ,  plant sperm cell

Literature:

• The PASTICCINO genes of Arabidopsis thaliana are involved in the control of cell division and differentiation.   DOI:  10.1242/dev.125.5.909 ;  PMID:  9449673
• Mutation in the Arabidopsis PASTICCINO1 gene, which encodes a new FK506-binding protein-like protein, has a dramatic effect on plant development.   DOI:  10.1128/MCB.18.5.3034 ;  PMID:  9566922
• Pasticcino2 is a protein tyrosine phosphatase-like involved in cell proliferation and differentiation in Arabidopsis.   DOI:  10.1046/j.1365-313x.2002.01456.x ;  PMID:  12472687
• The Arabidopsis gene PEPINO/PASTICCINO2 is required for proliferation control of meristematic and non-meristematic cells and encodes a putative anti-phosphatase.   DOI:  10.1007/s00427-002-0273-9 ;  PMID:  12459923
• Hormonal control of cell proliferation requires PASTICCINO genes.   DOI:  10.1104/pp.102.019026 ;  PMID:  12857804
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Very-long-chain fatty acids are involved in polar auxin transport and developmental patterning in Arabidopsis.   DOI:  10.1105/tpc.109.071209 ;  PMID:  20145257
• A novel high-throughput in vivo molecular screen for shade avoidance mutants identifies a novel phyA mutation.   DOI:  10.1093/jxb/err062 ;  PMID:  21398429
• Very-long-chain fatty acids are required for cell plate formation during cytokinesis in Arabidopsis thaliana.   DOI:  10.1242/jcs.074575 ;  PMID:  21896643
• Acyl-lipid metabolism.   DOI:  10.1199/tab.0161 ;  PMID:  23505340
• The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis.   DOI:  10.1371/journal.pgen.1005817 ;  PMID:  26828932
• Correction: The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis.   DOI:  10.1371/journal.pgen.1005958 ;  PMID:  27011024
• Cuticular wax biosynthesis is positively regulated by WRINKLED4, an AP2/ERF-type transcription factor, in Arabidopsis stems.   DOI:  10.1111/tpj.13248 ;  PMID:  27337244
• Research progress on the autonomous flowering time pathway in Arabidopsis.   DOI:  10.1007/s12298-017-0458-3 ;  PMID:  28878488
• Differential impact of heat stress on the expression of chloroplast-encoded genes.   DOI:  10.1016/j.plaphy.2018.05.023 ;  PMID:  29852366
• Arabidopsis Bax inhibitor-1 interacts with enzymes related to very-long-chain fatty acid synthesis.   DOI:  10.1007/s10265-018-01081-8 ;  PMID:  30604175
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• Protein-protein interactions in fatty acid elongase complexes are important for very-long-chain fatty acid synthesis.   DOI:  10.1093/jxb/erab543 ;  PMID:  35560210
• Tackling functional redundancy of Arabidopsis fatty acid elongase complexes.   DOI:  10.3389/fpls.2023.1107333 ;  PMID:  36798704

Sequences: