Gene Details:

• Gene ID: AT5G08020
• Gene Symbol: ATRPA70B, RPA1B, RPA70B
• Gene Name: ARABIDOPSIS THALIANA RPA70-KDA SUBUNIT B, Replication Protein A 1B, RPA70-kDa subunit B
• Description: RPA70-kDa subunit B;(source:Araport11)
• TAIR Accession: locus:2142808
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G08020.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0007004  — involved in — telomere maintenance via telomerase
• GO:0006281  — acts upstream of or within — DNA repair
• GO:0051321  — involved in — meiotic cell cycle
• GO:0010224  — acts upstream of or within — response to UV-B
• GO:0000724  — involved in — double-strand break repair via homologous recombination
• GO:0005662  — part of — DNA replication factor A complex
• GO:0006289  — involved in — nucleotide-excision repair
• GO:0003684  — enables — damaged DNA binding
• GO:0005634  — located in — nucleus
• GO:0043047  — enables — single-stranded telomeric DNA binding

Germplasm Phenotype:

• SALK_088429  — Reduced levels of methionine.
• SALK_088429C  — This mutant does not differ visibly from a wild type plant when grown under normal conditions. A UV-B dose during the first week of growth on normal media affects the atrpa70b mutant and wild-type seedlings similarly, although the mutants have an increased level of leaf yellowing. After a longer period of exposure to UV-B, the level of chlorophyll A and B is reduced to a greater extent in rpa70b mutants than in wild-type, and root growth is more inhibited in the mutants. Treatment with MMS also causes a greater inhibition of root growth in rpa70b mutants than in wild-type seedlings. In contrast, the mutants show a wild-type level of sensitivity to H2O2 in root growth assays.

Function-related keywords:

• root ,  plant sperm cell

Literature:

• Diversification of genes encoding mei2 -like RNA binding proteins in plants.   DOI:  10.1023/B:PLAN.0000040819.33383.b6 ;  PMID:  15356386
• Components of nucleotide excision repair and DNA damage tolerance in Arabidopsis thaliana.   DOI:  10.1002/em.20094 ;  PMID:  15645454
• Two types of replication protein A in seed plants.   DOI:  10.1111/j.1742-4658.2005.04719.x ;  PMID:  15978034
• ROR1/RPA2A, a putative replication protein A2, functions in epigenetic gene silencing and in regulation of meristem development in Arabidopsis.   DOI:  10.1105/tpc.105.037507 ;  PMID:  16326925
• and ABA-regulated transcription networks in Arabidopsis by microarray analysis and promoter classification using a Relevance Vector Machine.   DOI:  10.1101/gr.4237406 ;  PMID:  16424108
• Proteomic investigation of the effect of salicylic acid on Arabidopsis seed germination and establishment of early defense mechanisms.   DOI:  10.1104/pp.106.082057 ;  PMID:  16679420
• Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice.   DOI:  10.1104/pp.107.101105 ;  PMID:  17556508
• Arabidopsis replication protein A 70a is required for DNA damage response and telomere length homeostasis.   DOI:  10.1093/pcp/pcp140 ;  PMID:  19812063
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication.   DOI:  10.1093/nar/gkt1292 ;  PMID:  24335281
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Molecular Evolution and Functional Diversification of Replication Protein A1 in Plants.   DOI:  10.3389/fpls.2016.00033 ;  PMID:  26858742
• Functional Diversification of Replication Protein A Paralogs and Telomere Length Maintenance in Arabidopsis.   DOI:  10.1534/genetics.120.303222 ;  PMID:  32532801

Sequences: