Information report for AT5G08020
Gene Details
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Functional Descriptions
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
- GO:0007004 — involved in — telomere maintenance via telomerase
- GO:0006281 — acts upstream of or within — DNA repair
- GO:0051321 — involved in — meiotic cell cycle
- GO:0010224 — acts upstream of or within — response to UV-B
- GO:0000724 — involved in — double-strand break repair via homologous recombination
- GO:0005662 — part of — DNA replication factor A complex
- GO:0006289 — involved in — nucleotide-excision repair
- GO:0003684 — enables — damaged DNA binding
- GO:0005634 — located in — nucleus
- GO:0043047 — enables — single-stranded telomeric DNA binding
- SALK_088429 — Reduced levels of methionine.
- SALK_088429C — This mutant does not differ visibly from a wild type plant when grown under normal conditions. A UV-B dose during the first week of growth on normal media affects the atrpa70b mutant and wild-type seedlings similarly, although the mutants have an increased level of leaf yellowing. After a longer period of exposure to UV-B, the level of chlorophyll A and B is reduced to a greater extent in rpa70b mutants than in wild-type, and root growth is more inhibited in the mutants. Treatment with MMS also causes a greater inhibition of root growth in rpa70b mutants than in wild-type seedlings. In contrast, the mutants show a wild-type level of sensitivity to H2O2 in root growth assays.
Functional Keywords
Literature and News
- Diversification of genes encoding mei2 -like RNA binding proteins in plants. DOI: 10.1023/B:PLAN.0000040819.33383.b6 ; PMID: 15356386
- Components of nucleotide excision repair and DNA damage tolerance in Arabidopsis thaliana. DOI: 10.1002/em.20094 ; PMID: 15645454
- Two types of replication protein A in seed plants. DOI: 10.1111/j.1742-4658.2005.04719.x ; PMID: 15978034
- ROR1/RPA2A, a putative replication protein A2, functions in epigenetic gene silencing and in regulation of meristem development in Arabidopsis. DOI: 10.1105/tpc.105.037507 ; PMID: 16326925
- and ABA-regulated transcription networks in Arabidopsis by microarray analysis and promoter classification using a Relevance Vector Machine. DOI: 10.1101/gr.4237406 ; PMID: 16424108
- Proteomic investigation of the effect of salicylic acid on Arabidopsis seed germination and establishment of early defense mechanisms. DOI: 10.1104/pp.106.082057 ; PMID: 16679420
- Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice. DOI: 10.1104/pp.107.101105 ; PMID: 17556508
- Arabidopsis replication protein A 70a is required for DNA damage response and telomere length homeostasis. DOI: 10.1093/pcp/pcp140 ; PMID: 19812063
- Systematic identification of functional plant modules through the integration of complementary data sources. DOI: 10.1104/pp.112.196725 ; PMID: 22589469
- Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication. DOI: 10.1093/nar/gkt1292 ; PMID: 24335281
- Endogenous Arabidopsis messenger RNAs transported to distant tissues. DOI: 10.1038/nplants.2015.25 ; PMID: 27247031
- Molecular Evolution and Functional Diversification of Replication Protein A1 in Plants. DOI: 10.3389/fpls.2016.00033 ; PMID: 26858742
- Functional Diversification of Replication Protein A Paralogs and Telomere Length Maintenance in Arabidopsis. DOI: 10.1534/genetics.120.303222 ; PMID: 32532801
Gene Resources
- UniProt: A0A178UED9
- EMBL: CACSHJ010000096, LUHQ01000005
- AlphaFoldDB: A0A178UED9
- EnsemblPlants: AT5G08020.1
- Gramene: AT5G08020.1
- KEGG: ath:AT5G08020
- Orthologous matrix: FNSYAML
- ExpressionAtlas: AT5G08020
- InterPro: IPR004365, IPR004591, IPR007199
- PANTHER: PTHR47165, PTHR47165:SF4
- SUPFAM: SSF50249
- Gene3D: 2.40.50.140
- OrthoDB: A0A178UED9
- SWISS-MODEL: A0A178UED9
- Conserved Domain Database: cd04474, cd04475, cd04476
Sequences
cDNA Sequence
- >AT5G08020.1
AAAACGAGAATAAAATTCGGCGGGAATAATTAACGAAAAATCTAATAGCTCCCGCGCAAATCTTTCTTTTACAAAACAAAACCATTTTGCTTCCCATTTCCTGTGAATTCTAAAGAGAAAGAAGAGATAGAGCTAGAGATTAAGATAGAGATGGAGAACTCAGTGACCCAAGATGGTATCGCGACAGTATTAGCCAATCAATCCCTTGATTCCTCCTCTGTTAGACCCGAAATTGTTGTTCAAGTCGTGGATCTTAAGCCTGCTGGAAATCGATATACGTTTAGTGCCAATGATGGAAAGATGAAGATTAAAGCAATGTTACCAGCGACTTTGACTTCTGATATCATCTCTGGAAAGATTCAGAATCTGGGTCTTATTCGTCTCCTTGAGTATACCGTCAATGATATTCCAGGCAAATCAGAAGAAAAATATATGCTTATAACAAAATGTGAGGCTGTTGCTTCTGCACTTGACTCAGAGATTAAGGCGGAGATTAAAGCTTCCACAGGCATAATGTTGAAACCCAAGCATGAGTTTGTTGCCAAATCAGCTTCACAGATTATCAATGAGCAAAGGGGAAATGCTGCACCTGCTGCAAGAATGGCTATGACCAGAAGGGTTCATCCTCTTGTGTCCTTGAACCCTTATCAAGGAAGTTGGACTATTAAAGTTCGTGTCACTAACAAAGGAGTCATGAGAACTTACAAAAATGCCAGAGGAGAAGGATGTGTGTTTAATGTGGAACTAACTGATGAGGAAGGAACACAGATTCAGGCAACAATGTTTAACGCAGCTGCAAGGAAGTTTTATGACAGATTCGAGATGGGAAAGGTGTACTATATATCCAGGGGATCACTTAAGCTTGCTAATAAGCAGTTCAAGACGGTTCAGAACGATTATGAGATGACCCTAAATGAGAATTCTGAGGTTGAAGAAGCTAGTAATGAAGAAATGTTTACCCCTGAAACTAAATTCAACTTTGTACCCATTGATGAGTTGGGTACATACGTGAATCAGAAAGACCTTATTGATGTTATCGGTGTTGTTCAAAGTGTTTCTCCTACCATGAGCATTAGAAGGAAGAACGACAATGAGATGATCCCAAAGAGAGATATAACTTTGGCTGATGAGACAAAGAAAACTGTTGTGGTGTCCCTTTGGAATGATCTAGCAACTGGCATTGGCCAAGAACTGCTGGACATGGCTGATAATCACCCTGTTATCGCGATTAAATCTCTTAAAGTTGGAGCTTTTCAAGGTGTTTCATTGTCTACTATCAGCAGAAGCAATGTGGTGATAAACCCTAATTCTCCAGAAGCTACAAAGTTGAAATCTTGGTATGATGCTGAAGGGAAAGAGACATCTATGTCTGCTATTGGTTCTGGGATGAGTTCTTCTGCCAACAACGGATCAAGATCCATGTATTCTGACAGAGTTTTTCTTTCTCACATCACAAGCAATCCCTCTTTAGGCGAGGAGAAGCCTGTATTCTTCAGCACTAGAGCTTACATAAGCTTCATCAAGCCAGACCAAACAATGTGGTACCGTGCTTGCAAGACCTGTAACAAGAAAGTTACTGAAGCAATGGACTCTGGTTATTGGTGTGAAAGTTGTCAGAAAAAGGACCAAGAATGCAGTTTAAGGTATATAATGGCGGTGAAAGTCTCCGACTCAACTGGTGAAACTTGGTTATCTGCATTCAATGATGAAGCAGAGAAGATTATCGGCTGCACAGCTGATGATCTCAATGATCTAAAATCAGAGGAAGGTGAAGTGAATGAGTTTCAGACAAAACTGAAAGAAGCTACTTGGTCATCTCATCTCTTCCGGATTAGTGTTTCTCAGCAAGAGTATAACAGTGAGAAGAGACAGAGGATAACTGTAAGAGGTGTTTCTCCAATTGACTTTGCTGCTGAAACAAGATTATTGCTCCAAGACATTTCCAAGAACAAGACATCTCAGTAATTCTAACTTTTAGCATGTTTTGTCTGGTTTTGTCAAAGAGTCCCAAAGTTGTGAGTTTTTCTGCAGTCGGTTATAGTAGTTCATGTCATTAGAGAATTGACTTTTAAATCTTTGTAAGTGTTCCAACAATCAATTCAGAGAGCCATTTGGAAAAAGTAGAAGCAATATATTATGAAATCGAA
CDS Sequence
Protein Sequence