Gene Details:

• Gene ID: AT5G06310
• Gene Symbol: AtPOT1b
• Gene Name: protection of telomeres 1b
• Description: Nucleic acid-binding, OB-fold-like protein;(source:Araport11)
• TAIR Accession: locus:2164295
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G06310.1

Gene Ontology:

• GO:0051974  — involved in — negative regulation of telomerase activity
• GO:0032210  — involved in — regulation of telomere maintenance via telomerase
• GO:0005515  — enables — protein binding
• GO:0000723  — involved in — telomere maintenance
• GO:0098505  — enables — G-rich strand telomeric DNA binding
• GO:0016233  — involved in — telomere capping
• GO:0000783  — part of — nuclear telomere cap complex
• GO:0043047  — enables — single-stranded telomeric DNA binding
• GO:0005634  — located in — nucleus
• GO:0003723  — enables — RNA binding
• GO:0010521  — enables — telomerase inhibitor activity

Literature:

• The Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protection.   DOI:  10.1128/MCB.25.17.7725-7733.2005 ;  PMID:  16107718
• Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance.   DOI:  10.1038/sj.emboj.7601792 ;  PMID:  17627276
• Arabidopsis POT1A interacts with TERT-V(I8), an N-terminal splicing variant of telomerase.   DOI:  10.1242/jcs.004119 ;  PMID:  17911168
• POT1-independent single-strand telomeric DNA binding activities in Brassicaceae.   DOI:  10.1111/j.1365-313X.2009.03837.x ;  PMID:  19228335
• Alternative splicing of Pot1 (Protection of telomere)-like genes in Arabidopsis thaliana.   DOI:  10.1266/ggs.80.41 ;  PMID:  15824455
• Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specificity and kinetics.   DOI:  10.1042/BJ20082195 ;  PMID:  19102728
• POT1 proteins in green algae and land plants: DNA-binding properties and evidence of co-evolution with telomeric DNA.   DOI:  10.1093/nar/gkp785 ;  PMID:  19783822
• Two RNA subunits and POT1a are components of Arabidopsis telomerase.   DOI:  10.1073/pnas.1013021107 ;  PMID:  21164032
• Evolution of the Telomere-Associated Protein POT1a in Arabidopsis thaliana Is Characterized by Positive Selection to Reinforce Protein-Protein Interaction.   DOI:  10.1093/molbev/msv025 ;  PMID:  25697340
• Evolution of Arabidopsis protection of telomeres 1 alters nucleic acid recognition and telomerase regulation.   DOI:  10.1093/nar/gkw807 ;  PMID:  27651456
• Interactions of putative telomere-binding proteins in Arabidopsis thaliana: identification of functional TRF2 homolog in plants.   DOI:  10.1016/j.febslet.2004.11.021 ;  PMID:  15589838
• Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance.   DOI:  10.1038/sj.emboj.7601792 ;  PMID:  17627276
• Mapping of interaction domains of putative telomere-binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana.   DOI:  10.1016/j.febslet.2008.03.034 ;  PMID:  18387366

Sequences: