Gene Details:

• Gene ID: AT5G04950
• Gene Symbol: ATNAS1, NAS1
• Gene Name: ARABIDOPSIS THALIANA NICOTIANAMINE SYNTHASE 1, nicotianamine synthase 1
• Description: nicotianamine synthase 1;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G04950.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)

Function-related keywords:

• root ,  shoot system ,  root

Literature:

• Genes that are uniquely stress regulated in salt overly sensitive (sos) mutants.   DOI:  10.1104/pp.126.1.363 ;  PMID:  11351099
• Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis.   DOI:  10.1074/jbc.M309338200 ;  PMID:  13129917
• Microarray analysis of E2Fa-DPa-overexpressing plants uncovers a cross-talking genetic network between DNA replication and nitrogen assimilation.   DOI:  10.1242/jcs.00715 ;  PMID:  12953064
• Comparative microarray analysis of Arabidopsis thaliana and Arabidopsis halleri roots identifies nicotianamine synthase, a ZIP transporter and other genes as potential metal hyperaccumulation factors.   DOI:  10.1046/j.1365-313x.2003.01960.x ;  PMID:  14690510
• Comprehensive comparison of auxin-regulated and brassinosteroid-regulated genes in Arabidopsis.   DOI:  10.1104/pp.103.034736 ;  PMID:  15047898
• Transcriptional profiling by cDNA-AFLP and microarray analysis reveals novel insights into the early response to ethylene in Arabidopsis.   DOI:  10.1111/j.1365-313X.2004.02156.x ;  PMID:  15272873
• The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response.   DOI:  10.1105/tpc.104.024315 ;  PMID:  15539473
• Loss of TIP1;1 aquaporin in Arabidopsis leads to cell and plant death.   DOI:  10.1111/j.1365-313X.2004.02265.x ;  PMID:  15584951
• Analysis of sequence, map position, and gene expression reveals conserved essential genes for iron uptake in Arabidopsis and tomato.   DOI:  10.1104/pp.104.047233 ;  PMID:  15531708
• Zinc-dependent global transcriptional control, transcriptional deregulation, and higher gene copy number for genes in metal homeostasis of the hyperaccumulator Arabidopsis halleri.   DOI:  10.1104/pp.105.076232 ;  PMID:  16844841
• Large expression differences in genes for iron and zinc homeostasis, stress response, and lignin biosynthesis distinguish roots of Arabidopsis thaliana and the related metal hyperaccumulator Thlaspi caerulescens.   DOI:  10.1104/pp.106.082073 ;  PMID:  16998091
• The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses.   DOI:  10.1104/pp.109.136374 ;  PMID:  19304929
• Ethylene and nitric oxide involvement in the up-regulation of key genes related to iron acquisition and homeostasis in Arabidopsis.   DOI:  10.1093/jxb/erq203 ;  PMID:  20627899
• Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana.   DOI:  10.1186/1471-2229-11-87 ;  PMID:  21592396
• Vacuolar nicotianamine has critical and distinct roles under iron deficiency and for zinc sequestration in Arabidopsis.   DOI:  10.1105/tpc.111.095042 ;  PMID:  22374397
• Heavy Metals Need Assistance: The Contribution of Nicotianamine to Metal Circulation Throughout the Plant and the Arabidopsis NAS Gene Family.   DOI:  10.3389/fpls.2011.00069 ;  PMID:  22639605
• Nicotianamine functions in the Phloem-based transport of iron to sink organs, in pollen development and pollen tube growth in Arabidopsis.   DOI:  10.1105/tpc.112.099077 ;  PMID:  22706286
• Abscisic acid alleviates iron deficiency by promoting root iron reutilization and transport from root to shoot in Arabidopsis.   DOI:  10.1111/pce.12203 ;  PMID:  24111973
• Rice nicotianamine synthase localizes to particular vesicles for proper function.   DOI:  10.4161/psb.28660 ;  PMID:  24704865
• ZAT10 plays dual roles in cadmium uptake and detoxification in Arabidopsis.   DOI:  10.3389/fpls.2022.994100 ;  PMID:  36110357
• Genes that are uniquely stress regulated in salt overly sensitive (sos) mutants.   DOI:  10.1104/pp.126.1.363 ;  PMID:  11351099
• Map-based cloning of chloronerva, a gene involved in iron uptake of higher plants encoding nicotianamine synthase.   DOI:  10.1073/pnas.96.12.7098 ;  PMID:  10359845
• Isolation, characterization and cDNA cloning of nicotianamine synthase from barley. A key enzyme for iron homeostasis in plants.   DOI:  10.1046/j.1432-1327.1999.00717.x ;  PMID:  10491178

Sequences: