Gene Details:

• Gene ID: AT5G02500
• Gene Symbol: AT-HSC70-1, AtHsp70-1, HSC70, HSC70-1, HSP70-1
• Gene Name: ARABIDOPSIS THALIANA HEAT SHOCK COGNATE PROTEIN 70-1, HEAT SHOCK COGNATE PROTEIN 70, heat shock cognate protein 70-1, HEAT SHOCK PROTEIN 70-1
• Description: heat shock cognate protein 70-1;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G02500.1     AT5G02500.2

Plant Ontology Annotations:

• PO:0000282  — trichome — tricoma (Spanish, exact), 毛茸、糸状体、毛 (Japanese, exact), seta (related), setae (related), capilli (narrow), capillus (narrow), cilia (narrow), cilium (narrow), glochid (narrow), glochidia (narrow), glochidium (narrow), hair (narrow), lepides (narrow), lepis (narrow), non-secretory trichome (narrow), scale (narrow), squama (narrow), squamae (narrow), squamella (narrow), squamellae (narrow), squamule (narrow), barb trichome (broad), bristle (broad)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000293  — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)

Function-related keywords:

• trichome ,  shoot axis apex ,  leaf lamina base ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  pollen ,  guard cell

Literature:

• Identification of an Arabidopsis thaliana cDNA encoding a HSP70-related protein belonging to the HSP110/SSE1 subfamily.   DOI:  10.1016/0014-5793(96)00640-0 ;  PMID:  8706819
• The cellular level of PR500, a protein complex related to the 19S regulatory particle of the proteasome, is regulated in response to stresses in plants.   DOI:  10.1091/mbc.12.2.383 ;  PMID:  11179422
• Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family.   DOI:  10.1104/pp.126.2.789 ;  PMID:  11402207
• The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress.   DOI:  10.1074/jbc.M209694200 ;  PMID:  12482876
• A proteomic study of the arabidopsis nuclear matrix.   DOI:  10.1002/jcb.10624 ;  PMID:  14505352
• Analysis of the Arabidopsis nuclear proteome and its response to cold stress.   DOI:  10.1046/j.1365-313x.2003.01907.x ;  PMID:  14617066
• Co-immunoprecipitation of Hsp101 with cytosolic Hsc70.   DOI:  10.1016/j.plaphy.2004.10.006 ;  PMID:  15763661
• Virus induction of heat shock protein 70 reflects a general response to protein accumulation in the plant cytosol.   DOI:  10.1104/pp.104.058958 ;  PMID:  15805473
• Identification and functional characterization of the BAG protein family in Arabidopsis thaliana.   DOI:  10.1074/jbc.M511794200 ;  PMID:  16636050
• Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses.   DOI:  10.1105/tpc.107.051896 ;  PMID:  18065690
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Altered expression of cytosolic/nuclear HSC70-1 molecular chaperone affects development and abiotic stress tolerance in Arabidopsis thaliana.   DOI:  10.1093/jxb/erp109 ;  PMID:  19443614
• Genomic analysis of the Hsp70 superfamily in Arabidopsis thaliana.   DOI:  10.1379/1466-1268(2001)006<0201:gaoths>2.0.co;2 ;  PMID:  11599561
• WPP-domain proteins mimic the activity of the HSC70-1 chaperone in preventing mistargeting of RanGAP1-anchoring protein WIT1.   DOI:  10.1104/pp.109.143404 ;  PMID:  19617588
• Structure and activity of JAC1 J-domain implicate the involvement of the cochaperone activity with HSC70 in chloroplast photorelocation movement.   DOI:  10.4161/psb.5.12.13915 ;  PMID:  21139434
• AtHsp70-15-deficient Arabidopsis plants are characterized by reduced growth, a constitutive cytosolic protein response and enhanced resistance to TuMV.   DOI:  10.1111/j.1365-313X.2011.04558.x ;  PMID:  21418353
• OEP61 is a chaperone receptor at the plastid outer envelope.   DOI:  10.1042/BJ20110448 ;  PMID:  21612577
• Proteomic analyses of apoplastic proteins from germinating Arabidopsis thaliana pollen.   DOI:  10.1016/j.bbapap.2011.07.013 ;  PMID:  21798377
• The Mediator complex in plants: structure, phylogeny, and expression profiling of representative genes in a dicot (Arabidopsis) and a monocot (rice) during reproduction and abiotic stress.   DOI:  10.1104/pp.111.188300 ;  PMID:  22021418
• Proteomics investigation of endogenous S-nitrosylation in Arabidopsis.   DOI:  10.1016/j.bbrc.2011.11.036 ;  PMID:  22115780
• Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis.   DOI:  10.1104/pp.15.00970 ;  PMID:  26408532
• Interaction network of tobacco etch potyvirus NIa protein with the host proteome during infection.   DOI:  10.1186/s12864-016-2394-y ;  PMID:  26830344
• CaM/BAG5/Hsc70 signaling complex dynamically regulates leaf senescence.   DOI:  10.1038/srep31889 ;  PMID:  27539741
• A subclass of HSP70s regulate development and abiotic stress responses in Arabidopsis thaliana.   DOI:  10.1007/s10265-016-0900-6 ;  PMID:  28004282
• Arabidopsis HSP70-16 is required for flower opening under normal or mild heat stress temperatures.   DOI:  10.1111/pce.13480 ;  PMID:  30426513
• Protein and metabolite composition of Arabidopsis stress granules.   DOI:  10.1111/nph.15690 ;  PMID:  30664249
• Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase.   DOI:  10.1038/s41477-019-0378-z ;  PMID:  30833711
• Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method.   DOI:  10.3390/biom10040661 ;  PMID:  32344669
• AtHsc70-1 negatively regulates the basal heat tolerance in Arabidopsis thaliana through affecting the activity of HsfAs and Hsp101.   DOI:  10.1111/tpj.14883 ;  PMID:  32573848
• The CBP/p300 histone acetyltransferases function as plant-specific MEDIATOR subunits in Arabidopsis.   DOI:  10.1111/jipb.13052 ;  PMID:  33325122
• Regulation of heat shock proteins 70 and their role in plant immunity.   DOI:  10.1093/jxb/erab549 ;  PMID:  35022724
• Mitochondrial HSC70-1 Regulates Polar Auxin Transport through ROS Homeostasis in Arabidopsis Roots.   DOI:  10.3390/antiox11102035 ;  PMID:  36290758
• CASC3 Biomolecular Condensates Restrict Turnip Crinkle Virus by Limiting Host Factor Availability.   DOI:  10.1016/j.jmb.2023.167956 ;  PMID:  36642157
• Analysis of the Arabidopsis nuclear proteome and its response to cold stress.   DOI:  10.1046/j.1365-313x.2003.01907.x ;  PMID:  14617066
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209
• Cell-specific protein profiling in Arabidopsis thaliana trichomes: identification of trichome-located proteins involved in sulfur metabolism and detoxification.   DOI:  10.1016/j.phytochem.2004.03.026 ;  PMID:  15276459
• Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions.   DOI:  10.1091/mbc.e04-09-0791 ;  PMID:  15496452
• High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome.   DOI:  10.1007/s11103-005-0699-3 ;  PMID:  15821981
• Proteome mapping of mature pollen of Arabidopsis thaliana.   DOI:  10.1002/pmic.200402011 ;  PMID:  16247729
• Arabidopsis cell wall proteome defined using multidimensional protein identification technology.   DOI:  10.1002/pmic.200500046 ;  PMID:  16287169
• The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses.   DOI:  10.1002/pmic.200500543 ;  PMID:  16502469
• A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.   DOI:  10.1074/mcp.M600250-MCP200 ;  PMID:  17151019
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.   DOI:  10.1074/mcp.M700099-MCP200 ;  PMID:  17644812
• Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses.   DOI:  10.1105/tpc.107.051896 ;  PMID:  18065690
• Identification by 2-D DIGE of apoplastic proteins regulated by oligogalacturonides in Arabidopsis thaliana.   DOI:  10.1002/pmic.200700523 ;  PMID:  18324730
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.   DOI:  10.1016/j.phytochem.2008.04.007 ;  PMID:  18538804
• WPP-domain proteins mimic the activity of the HSC70-1 chaperone in preventing mistargeting of RanGAP1-anchoring protein WIT1.   DOI:  10.1104/pp.109.143404 ;  PMID:  19617588
• Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism.   DOI:  10.1021/pr1009433 ;  PMID:  21166475
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464
• A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.   DOI:  10.1074/mcp.M600250-MCP200 ;  PMID:  17151019
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.   DOI:  10.1074/mcp.M700099-MCP200 ;  PMID:  17644812
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.   DOI:  10.1016/j.phytochem.2008.04.007 ;  PMID:  18538804
• Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism.   DOI:  10.1021/pr1009433 ;  PMID:  21166475

Sequences: