Gene Details:

• Gene ID: AT5G02220
• Gene Symbol: SMR4
• Gene Name: SIAMESE-RELATED 4
• Description: cyclin-dependent kinase inhibitor;(source:Araport11)
• TAIR Accession: locus:2185213
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G02220.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)

Gene Ontology:

• GO:0051726  — acts upstream of or within — regulation of cell cycle
• GO:0098542  — acts upstream of or within — defense response to other organism
• GO:0140013  — acts upstream of or within — meiotic nuclear division
• GO:0005515  — enables — protein binding
• GO:0016070  — acts upstream of or within — RNA metabolic process
• GO:0032875  — involved in — regulation of DNA endoreduplication
• GO:0019219  — acts upstream of or within — regulation of nucleobase-containing compound metabolic process
• GO:0051301  — acts upstream of or within — cell division
• GO:0006810  — acts upstream of or within — transport
• GO:0008104  — acts upstream of or within — protein localization
• GO:0005634  — located in — nucleus
• GO:0005634  — is active in — nucleus

Function-related keywords:

• shoot axis apex ,  plant embryo ,  flower ,  hypocotyl

Literature:

• ATR and ATM play both distinct and additive roles in response to ionizing radiation.   DOI:  10.1111/j.1365-313X.2006.02931.x ;  PMID:  17227549
• Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.   DOI:  10.1093/molbev/msq204 ;  PMID:  20736450
• Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana.   DOI:  10.1038/msb.2010.53 ;  PMID:  20706207
• The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species.   DOI:  10.1105/tpc.113.118943 ;  PMID:  24399300
• Suppressor of Gamma Response 1 Modulates the DNA Damage Response and Oxidative Stress Response in Leaves of Cadmium-Exposed Arabidopsis thaliana.   DOI:  10.3389/fpls.2020.00366 ;  PMID:  32308663
• A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis.   DOI:  10.1038/s41467-022-29316-2 ;  PMID:  35351906

Sequences: