Gene Details:
- Gene ID: AT4G31920
- Gene Symbol: ARR10, RR10
- Gene Name: response regulator 10, response regulator 10
- Description: response regulator 10;(source:Araport11)
- TAIR Accession: locus:2116587
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000025 — root tip — punta de la raíz (Spanish, exact), 根端 (Japanese, exact)
- PO:0000036 — leaf vascular system — sistema vascular de la hoja (Spanish, exact), 葉維管系 (Japanese, exact), leaf venation (related)
- PO:0005660 — hydathode — hidatodo (Spanish, exact), 排水組織 (Japanese, exact)
- PO:0006079 — shoot system meristem — meristema del epiblasto (epiblastema) (Spanish, exact), シュート分裂組織 (Japanese, exact)
- PO:0006339 — juvenile vascular leaf — hoja juvenil (Spanish, exact), 維管束系幼葉 (Japanese, exact)
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
Gene Ontology:
- GO:0009736 — acts upstream of or within — cytokinin-activated signaling pathway
- GO:0080113 — acts upstream of or within — regulation of seed growth
- GO:0080036 — acts upstream of or within — regulation of cytokinin-activated signaling pathway
- GO:0080036 — involved in — regulation of cytokinin-activated signaling pathway
- GO:0010380 — acts upstream of or within — regulation of chlorophyll biosynthetic process
- GO:0009414 — acts upstream of or within — response to water deprivation
- GO:0000156 — enables — phosphorelay response regulator activity
- GO:0003700 — enables — DNA-binding transcription factor activity
- GO:0071368 — acts upstream of or within — cellular response to cytokinin stimulus
- GO:0080022 — acts upstream of or within — primary root development
- GO:0010082 — involved in — regulation of root meristem growth
- GO:0010082 — acts upstream of or within — regulation of root meristem growth
- GO:0005515 — enables — protein binding
- GO:0048364 — acts upstream of or within — root development
- GO:0009735 — acts upstream of or within — response to cytokinin
- GO:0048367 — acts upstream of or within — shoot system development
- GO:0005634 — located in — nucleus
- GO:0009507 — located in — chloroplast
- GO:1990110 — acts upstream of or within — callus formation
- GO:0010492 — acts upstream of or within — maintenance of shoot apical meristem identity
- GO:0031537 — acts upstream of or within — regulation of anthocyanin metabolic process
Germplasm Phenotype:
- CS39989 — No visible phenotype.
- CS39990 — Reduced sensitivity to cytokinin inhibition of primary root and hypocotyl growth.
- CS39991 — Reduced sensitivity to cytokinin inhibition of primary root and hypocotyl growth.
- CS39992 — Almost complete loss of sensitivity to cytokinin inhibition of primary root and hypocotyl growth; Premature termination of primary root growth; Altered vascular morphogenesis; Reduced stature; Increased light sensitivity; Altered chlorophyll content.
- CS6369 — No visible phenotype; average height = 36 cm.
- CS6987 — Reduced sensitivity to cytokinin inhibition on root elongation and lateral root formation; no significant change in the sensitivity to ethylene.
- CS69876 — Hypersensitivity to cytokinin, reflected by short hypocotyl and root. Larger later leaves.
- CS69877 — Hypersensitivity to cytokinin, reflected by short hypocotyl and root. Larger later leaves.
- CS69878 — Hypersensitivity to cytokinin, reflected by short hypocotyl and root. Larger later leaves.
- CS69879 — Hypersensitivity to cytokinin, reflected by short hypocotyl and root. Larger later leaves.
- CS6990 — Reduced sensitivity to cytokinin inhibition on root elongation and lateral root formation; no significant change in the sensitivity to ethylene.
- CS6991 — Reduced sensitivity to cytokinin inhibition on root elongation and lateral root formation; no significant change in the sensitivity to ethylene.
- CS6993 — Reduced sensitivity to cytokinin inhibition on root elongation and lateral root formation; no significant change in the sensitivity to ethylene.
- arr1-3 arr10-5 arr12-1 — Higher levels of anthocyanins than WT under both drought and well- watered control conditions.
- arr1-3 arr10-5 arr12-1 — The triple mutant showed enhanced drought tolerance versus WT plants, enhanced cell membrane integrity, increased anthocyanin biosynthesis, abscisic acid (ABA) hypersensitivity, and reduced stomatal aperture, but not to altered stomatal density.
- arr1-3 arr10-5 arr12-1 — severe primary root abnormalities; premature termination of primary root growth; substantially reduced sensitivity to cytokinin in the hypocotyl growth response assay; smaller rosette diameter; altered chlorophyll and anthocyanin production.
Function-related keywords:
- root tip , leaf vascular system , hydathode , shoot system meristem , juvenile vascular leaf , shoot axis apex , leaf lamina base , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen
Literature:
- Compilation and characterization of Arabidopsis thaliana response regulators implicated in His-Asp phosphorelay signal transduction. DOI: 10.1093/oxfordjournals.pcp.a029600 ; PMID: 10501033
- Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. DOI: 10.1126/science.290.5499.2105 ; PMID: 11118137
- Two types of putative nuclear factors that physically interact with histidine-containing phosphotransfer (Hpt) domains, signaling mediators in His-to-Asp phosphorelay, in Arabidopsis thaliana. DOI: 10.1093/pcp/pce011 ; PMID: 11158442
- Two-component circuitry in Arabidopsis cytokinin signal transduction. DOI: 10.1038/35096500 ; PMID: 11574878
- Two-component signal transduction pathways in Arabidopsis. DOI: 10.1104/pp.005504 ; PMID: 12068096
- Type-B response regulators display overlapping expression patterns in Arabidopsis. DOI: 10.1104/pp.103.038109 ; PMID: 15173562
- Multiple type-B response regulators mediate cytokinin signal transduction in Arabidopsis. DOI: 10.1105/tpc.105.035451 ; PMID: 16227453
- Type-B ARR transcription factors, ARR10 and ARR12, are implicated in cytokinin-mediated regulation of protoxylem differentiation in roots of Arabidopsis thaliana. DOI: 10.1093/pcp/pcl040 ; PMID: 17132632
- Three type-B response regulators, ARR1, ARR10 and ARR12, play essential but redundant roles in cytokinin signal transduction throughout the life cycle of Arabidopsis thaliana. DOI: 10.1093/pcp/pcm165 ; PMID: 18037673
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development. DOI: 10.1105/tpc.108.059584 ; PMID: 18723577
- Interaction of a plant pseudo-response regulator with a calmodulin-like protein. DOI: 10.1016/j.bbrc.2010.07.016 ; PMID: 20627089
- CLE peptides can negatively regulate protoxylem vessel formation via cytokinin signaling. DOI: 10.1093/pcp/pcq129 ; PMID: 20802224
- Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. DOI: 10.1016/j.phytochem.2011.02.029 ; PMID: 21477822
- Cytokinin interplay with ethylene, auxin, and glucose signaling controls Arabidopsis seedling root directional growth. DOI: 10.1104/pp.111.175794 ; PMID: 21666052
- Cytokinins enhance sugar-induced anthocyanin biosynthesis in Arabidopsis. DOI: 10.1007/s10059-012-0114-2 ; PMID: 22699753
- Functional characterization of type-B response regulators in the Arabidopsis cytokinin response. DOI: 10.1104/pp.112.208736 ; PMID: 23482873
- Cytokinin as a mediator for regulating root system architecture in response to environmental cues. DOI: 10.4161/psb.27771 ; PMID: 24509549
- Gene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis. DOI: 10.1038/srep07197 ; PMID: 25425016
- PHABULOSA controls the quiescent center-independent root meristem activities in Arabidopsis thaliana. DOI: 10.1371/journal.pgen.1004973 ; PMID: 25730098
- Arabidopsis type B cytokinin response regulators ARR1, ARR10, and ARR12 negatively regulate plant responses to drought. DOI: 10.1073/pnas.1600399113 ; PMID: 26884175
- Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes. DOI: 10.1104/pp.16.00640 ; PMID: 27388681
- Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root. DOI: 10.1242/dev.132035 ; PMID: 27697901
- EXTRA-LARGE G PROTEINs Interact with E3 Ligases PUB4 and PUB2 and Function in Cytokinin and Developmental Processes. DOI: 10.1104/pp.16.00816 ; PMID: 27986866
- A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration. DOI: 10.1105/tpc.16.00863 ; PMID: 28389585
- Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL. DOI: 10.1105/tpc.16.00640 ; PMID: 28576846
- Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in Arabidopsis. DOI: 10.1073/pnas.1620749114 ; PMID: 28673986
- Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL. DOI: 10.1016/j.tplants.2017.08.007 ; PMID: 28886911
- Wounding Triggers Callus Formation via Dynamic Hormonal and Transcriptional Changes. DOI: 10.1104/pp.17.01035 ; PMID: 28904073
- Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. DOI: 10.1104/pp.17.00980 ; PMID: 29233938
- A B-ARR-mediated cytokinin transcriptional network directs hormone cross-regulation and shoot development. DOI: 10.1038/s41467-018-03921-6 ; PMID: 29686312
- ETR1 Integrates Response to Ethylene and Cytokinins into a Single Multistep Phosphorelay Pathway to Control Root Growth. DOI: 10.1016/j.molp.2019.05.012 ; PMID: 31176773
- Root-derived trans-zeatin cytokinin protects Arabidopsis plants against photoperiod stress. DOI: 10.1111/pce.13860 ; PMID: 32716064
- MPK3/6-induced degradation of ARR1/10/12 promotes salt tolerance in Arabidopsis. DOI: 10.15252/embr.202152457 ; PMID: 34402578
- Defective cytokinin signaling reprograms lipid and flavonoid gene-to-metabolite networks to mitigate high salinity in Arabidopsis. DOI: 10.1073/pnas.2105021118 ; PMID: 34815339
- The type-B response regulators ARR10, ARR12, and ARR18 specify the central cell in Arabidopsis. DOI: 10.1093/plcell/koac285 ; PMID: 36130292
- Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. DOI: 10.1126/science.290.5499.2105 ; PMID: 11118137
- Two-component circuitry in Arabidopsis cytokinin signal transduction. DOI: 10.1038/35096500 ; PMID: 11574878
Sequences:
cDNA Sequence
- >AT4G31920.1
GATTCTCCTCTGAAAATGTTTTTTGTTTTTTTCTTATGTCAAAAAGAAAATTTACCAGAAATGATTAAAATTTGAAAAGAGAATTCCATAAATGAGTTAATTCGCCAGTCTTGAAGATCATTACAGAGTTTTCAGAAACCATATGTAGTCTTAGATTCTCTTTTGCCAAAGAAGAAAATTTTACTCTGCCATACAACTTTTTGTCTCTTTCTCTACTAATAATAATAATCCGAACTTTGTTTGTTCTTCTACTTCAATTCATAATCTTTGACGGCGATGACTATGGAGCAAGAAATTGAAGTCTTGGACCAGTTTCCGGTTGGGATGAGAGTTCTTGCTGTTGACGATGACCAGACTTGTCTCCGTATTCTCCAGACTTTGCTTCAGCGCTGCCAATATCACGTTACAACAACGAATCAGGCACAGACCGCATTGGAGTTGTTGAGGGAGAACAAGAATAAGTTTGATCTTGTTATTAGCGATGTCGACATGCCAGACATGGATGGTTTCAAGCTGCTTGAGCTTGTTGGTCTTGAAATGGACTTACCTGTCATAATGTTATCTGCGCATAGCGATCCAAAGTATGTGATGAAAGGAGTCAAGCACGGTGCCTGTGATTATCTGCTTAAACCGGTTCGAATTGAGGAGCTTAAGAACATATGGCAACATGTTGTGAGAAAGAGCAAACTTAAGAAGAATAAGAGCAATGTGAGTAATGGTTCAGGAAACTGTGATAAAGCAAACAGAAAACGTAAAGAACAGTATGAAGAGGAGGAAGAGGAAGAAAGAGGGAATGATAATGATGATCCAACGGCGCAGAAGAAGCCTCGTGTTCTTTGGACGCATGAGCTGCACAATAAATTCCTAGCAGCTGTTGATCATTTAGGCGTTGAGAGAGCTGTTCCAAAAAAGATTCTAGATCTGATGAATGTTGACAAACTCACTAGAGAGAATGTTGCAAGCCACCTTCAGAAATTCCGCGTTGCTCTGAAGAAGGTGTCTGATGACGCCATTCAACAAGCTAACAGGGCGGCTATTGACTCACATTTTATGCAAATGAATTCTCAGAAAGGACTTGGTGGCTTCTACCACCACCACCGCGGAATACCTGTTGGATCCGGTCAGTTCCATGGTGGAACCACAATGATGAGGCATTACTCTTCAAATAGGAATCTTGGTCGTCTGAATTCCCTTGGAGCAGGAATGTTCCAACCAGTCTCATCATCGTTTCCTCGTAACCATAATGATGGAGGAAACATACTTCAGGGTTTGCCGCTAGAAGAGCTTCAGATCAACAACAACATCAACAGGGCTTTTCCAAGCTTTACTTCACAACAAAACTCTCCAATGGTAGCTCCCAGTAATCTGTTACTTCTCGAGGGTAACCCGCAGTCATCATCTTTACCCTCAAACCCGGGTTTTTCTCCTCATTTCGAGATCAGCAAGCGTCTAGAACATTGGTCAAACGCTGCATTGTCAACCAACATTCCACAGAGTGATGTTCATTCAAAACCTGACACCTTGGAATGGAATGCGTTCTGCGACTCAGCTAGTCCGCTAGTAAACCCAAACCTGGATACAAATCCGGCATCTCTCTGCAGAAACACGGGTTTTGGATCCACAAATGCTGCACAAACAGACTTCTTTTATCCATTACAGATGAATCAGCAGCCTGCAAACAACTCAGGTCCAGTGACAGAAGCTCAACTGTTTAGAAGTAGCAATCCAAACGAAGGTTTACTCATGGGACAACAGAAGCTTCAGAGTGGTTTGATGGCTTCTGATGCTGGTTCCTTAGATGATATAGTCAATTCCTTAATGACACAGGAACAGAGCCAATCTGATTTCTCGGAAGGTGATTGGGATTTGGATGGTTTAGCTCACTCGGAACATGCATACGAGAAACTCCATTTTCCCTTTTCTTTGTCAGCTTGAGAAACCTGTTTTATTCAGACACAATCAATTATTATTATCTTTTGGTTCTGTCTCTTCTCTCTTCTCTGTAATGAAAGTGTAAGCTATTGTTTACCGCTCCCCCACTGGTTTGAGCAACTTAGGAAGATCCAAATCCATAAATAAAATTCAAAAAGTACCCTCTTTGCTACAAATGTAAAGGTGTTTTGAAGAGGAAGTCAAAGTCTTCGTGTCTAAGTGCAAAATAACGTTAGAATC
CDS Sequence
Protein Sequence