Information report for AT4G29130
Gene Details
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Functional Descriptions
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- GO:0005739 — located in — mitochondrion
- GO:0006096 — involved in — glycolytic process
- GO:0010255 — acts upstream of or within — glucose mediated signaling pathway
- GO:0090332 — acts upstream of or within — stomatal closure
- GO:0005515 — enables — protein binding
- GO:0000325 — located in — plant-type vacuole
- GO:0051156 — involved in — glucose 6-phosphate metabolic process
- GO:2000032 — acts upstream of or within — regulation of secondary shoot formation
- GO:0008270 — enables — zinc ion binding
- GO:0005536 — enables — glucose binding
- GO:0010182 — acts upstream of or within — sugar mediated signaling pathway
- GO:0004340 — enables — glucokinase activity
- GO:0005829 — is active in — cytosol
- GO:0006006 — involved in — glucose metabolic process
- GO:0004396 — enables — hexokinase activity
- GO:0019320 — acts upstream of or within — hexose catabolic process
- GO:0008865 — enables — fructokinase activity
- GO:0012501 — acts upstream of or within — programmed cell death
- GO:0005739 — is active in — mitochondrion
- GO:0046835 — involved in — carbohydrate phosphorylation
- GO:0005634 — located in — nucleus
- GO:0010148 — acts upstream of or within — transpiration
- GO:0001678 — involved in — intracellular glucose homeostasis
- CS6383 — Addition of cytokinin promotes extensive shoot induction in mutant but not in WT calli.
- CS6383 — At the flowering stage, the mutant has a smaller root system, tiny leaves with delayed senescence, shorter petioles and inflorescences, and a reduced number of flowers and siliques. Trichomes are normal and flower size and shape, and produced fertile seeds (albeit in reduced number).
- CS6383 — Defect in elongation of hypocotyl, roots, and cotyledons in dim light (15 μmol/m2/s).
- CS6383 — Delayed leaf senescence.
- CS6383 — Glucose insensitivity; develop green cotyledons and leaves on 6% glucose MS medium under 50uE light intensity at 23-28C; develop small rosettes (dark-green leaves with short petiols) and small plants when grown on soil under 250 uE light intensity at 23-25C; nitrate antagonizes the sugar phenotypes
- CS6383 — Insensitive to high-glucose repression of chlorophyll accumulation in seedlings.
- CS6383 — Insensitive to high-glucose repression of cotyledon expansion, chlorophyll accumulation, true-leaf development and root elongation. The response is specific to glucose but not to osmotic changes.
- CS6383 — Leaves of the mutant have about one-half the glucose phosphorylation capacity of wild-type leaves when grown under low or high light conditions.
- CS6383 — Leaves remain small and dark green with little cell expansion under high light conditions, although the same number of leaves appeared at the same time as in the wild type.
- CS69135 — Reduced growth in roots, leaf and stem length, rosette size and inflorescence.
- CS69136 — Reduced growth in roots, leaf length, and rosette size. Intermediate growth phenotype between hxk1-3 and rgs1-2 single mutants.
- CS69140 — Reduced growth in roots, leaf and stem length, rosette size and inflorescence. YFP expression localized to the plasma membrane without glucose, and endocytosed upon D-glucose treatment.
- CS69141 — Reduced growth in roots, leaf and stem length, rosette size and inflorescence. YFP expression localized to the plasma membrane without glucose, and endocytosed upon D-glucose treatment.
- CS69142 — Reduced growth in roots, leaf and stem length, rosette size and inflorescence. YFP expression localized to the plasma membrane without glucose, and endocytosed upon D-glucose treatment.
- CS69153 — Reduced growth in roots, leaf and stem length, rosette size and inflorescence.
- SALK_070739 — Mutants do not display glucose mediated pollen tube growth inhibition.
- gin2-2 — Addition of cytokinin promotes extensive shoot induction in mutant but not in WT calli.
- gin2-2 — Insensitive to high-glucose repression of chlorophyll accumulation in seedlings.
- siz1-2 hxk1-1 — Decreased rosette diameter, decreased percentage of seed germination (more than either single mutant.)
Functional Keywords
- shoot axis apex , leaf lamina base , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , stamen , pollen
Literature and News
- Hexokinase as a sugar sensor in higher plants. DOI: 10.1105/tpc.9.1.5 ; PMID: 9014361
- Trehalose-6-phosphate synthase 1, which catalyses the first step in trehalose synthesis, is essential for Arabidopsis embryo maturation. DOI: 10.1046/j.1365-313x.2002.01220.x ; PMID: 11851922
- Sugar and hormone connections. DOI: 10.1016/S1360-1385(03)00011-6 ; PMID: 12663220
- Mechanisms of glucose signaling during germination of Arabidopsis. DOI: 10.1104/pp.103.020347 ; PMID: 12857824
- Regulation of root ion transporters by photosynthesis: functional importance and relation with hexokinase. DOI: 10.1105/tpc.013516 ; PMID: 12953122
- Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. DOI: 10.1105/tpc.016055 ; PMID: 14671022
- Glucose delays seed germination in Arabidopsis thaliana. DOI: 10.1007/s00425-003-1154-9 ; PMID: 14648119
- Mapping the Arabidopsis organelle proteome. DOI: 10.1073/pnas.0506958103 ; PMID: 16618929
- Mitochondria-associated hexokinases play a role in the control of programmed cell death in Nicotiana benthamiana. DOI: 10.1105/tpc.106.041509 ; PMID: 16920781
- ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown. DOI: 10.1007/s11103-006-9082-2 ; PMID: 17031512
- Regulatory functions of nuclear hexokinase1 complex in glucose signaling. DOI: 10.1016/j.cell.2006.09.028 ; PMID: 17081979
- Isozymes of plant hexokinase: occurrence, properties and functions. DOI: 10.1016/j.phytochem.2006.12.001 ; PMID: 17234224
- Expression and evolutionary features of the hexokinase gene family in Arabidopsis. DOI: 10.1007/s00425-008-0746-9 ; PMID: 18481082
- Glucosamine causes overproduction of reactive oxygen species, leading to repression of hypocotyl elongation through a hexokinase-mediated mechanism in Arabidopsis. DOI: 10.1016/j.jplph.2008.04.001 ; PMID: 18541338
- Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. DOI: 10.1104/pp.108.126375 ; PMID: 18775970
- Function of Arabidopsis hexokinase-like1 as a negative regulator of plant growth. DOI: 10.1093/jxb/erp252 ; PMID: 19706780
- Glucose signaling through nuclear hexokinase1 complex in Arabidopsis. DOI: 10.4161/psb.2.2.3894 ; PMID: 19704756
- Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. DOI: 10.1104/pp.109.147942 ; PMID: 20018591
- Heterologous expression of yeast Hxt2 in Arabidopsis thaliana alters sugar uptake, carbon metabolism and gene expression leading to glucose tolerance of germinating seedlings. DOI: 10.1007/s11103-010-9602-y ; PMID: 20101436
- Signaling role of fructose mediated by FINS1/FBP in Arabidopsis thaliana. DOI: 10.1371/journal.pgen.1001263 ; PMID: 21253566
- Relationship between hexokinase and cytokinin in the regulation of leaf senescence and seed germination. DOI: 10.1111/j.1438-8677.2010.00376.x ; PMID: 21489094
- Arabidopsis Hexokinase-Like1 and Hexokinase1 form a critical node in mediating plant glucose and ethylene responses. DOI: 10.1104/pp.112.195636 ; PMID: 22366209
- The Arabidopsis CstF64-Like RSR1/ESP1 Protein Participates in Glucose Signaling and Flowering Time Control. DOI: 10.3389/fpls.2012.00080 ; PMID: 22629280
- Analysis of Arabidopsis glucose insensitive growth mutants reveals the involvement of the plastidial copper transporter PAA1 in glucose-induced intracellular signaling. DOI: 10.1104/pp.111.191726 ; PMID: 22582133
- The role of hexokinase in plant sugar signal transduction and growth and development. DOI: 10.1023/a:1026501430422 ; PMID: 11197321
- an Arabidopsis thaliana Double Mutant by Exogenously Supplied Sugars. DOI: 10.3389/fpls.2012.00265 ; PMID: 23233856
- Soluble carbohydrates regulate auxin biosynthesis via PIF proteins in Arabidopsis. DOI: 10.1105/tpc.112.104794 ; PMID: 23209113
- Phosphorylation of D-allose by hexokinase involved in regulation of OsABF1 expression for growth inhibition in Oryza sativa L. DOI: 10.1007/s00425-013-1853-9 ; PMID: 23397192
- Sugar promotes vegetative phase change in Arabidopsis thaliana by repressing the expression of MIR156A and MIR156C. DOI: 10.7554/eLife.00260 ; PMID: 23538384
- Regulation of nitrate reduction in Arabidopsis WT and hxk1 mutant under C and N metabolites. DOI: 10.1111/ppl.12045 ; PMID: 23480350
- Master Regulators in Plant Glucose Signaling Networks. DOI: 10.1007/s12374-014-0902-7 ; PMID: 25530701
- Response of nitrate reductase activity and NIA genes expression in roots of Arabidopsis hxk1 mutant treated with selected carbon and nitrogen metabolites. DOI: 10.1016/j.plantsci.2014.10.008 ; PMID: 25480007
- Abscisic acid receptor PYRABACTIN RESISTANCE-LIKE 8, PYL8, is involved in glucose response and dark-induced leaf senescence in Arabidopsis. DOI: 10.1016/j.bbrc.2015.05.010 ; PMID: 25983319
- Involvement of Arabidopsis Hexokinase1 in Cell Death Mediated by Myo-Inositol Accumulation. DOI: 10.1105/tpc.15.00068 ; PMID: 26048869
- Hexokinase 1 is required for glucose-induced repression of bZIP63, At5g22920, and BT2 in Arabidopsis. DOI: 10.3389/fpls.2015.00525 ; PMID: 26236323
- Gibberellic Acid-Stimulated Arabidopsis6 Serves as an Integrator of Gibberellin, Abscisic Acid, and Glucose Signaling during Seed Germination in Arabidopsis. DOI: 10.1104/pp.15.00858 ; PMID: 26400990
- Sugar-induced plant growth is dependent on brassinosteroids. DOI: 10.1080/15592324.2015.1082700 ; PMID: 26340221
- Cooperative control between AtRGS1 and AtHXK1 in a WD40-repeat protein pathway in Arabidopsis thaliana. DOI: 10.3389/fpls.2015.00851 ; PMID: 26528314
- Metabolomic analysis reveals the relationship between AZI1 and sugar signaling in systemic acquired resistance of Arabidopsis. DOI: 10.1016/j.plaphy.2016.06.016 ; PMID: 27337039
- Glucose enhances indolic glucosinolate biosynthesis without reducing primary sulfur assimilation. DOI: 10.1038/srep31854 ; PMID: 27549907
- Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. DOI: 10.1007/s11103-016-0562-8 ; PMID: 27866313
- The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development. DOI: 10.1080/15592324.2017.1312241 ; PMID: 28467152
- Arabidopsis SFAR4 is a novel GDSL-type esterase involved in fatty acid degradation and glucose tolerance. DOI: 10.1186/s40529-015-0114-6 ; PMID: 28510842
- Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression. DOI: 10.1105/tpc.16.00877 ; PMID: 28684426
- Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. DOI: 10.3389/fpls.2017.02100 ; PMID: 29321786
- Glucose triggers stomatal closure mediated by basal signaling through HXK1 and PYR/RCAR receptors in Arabidopsis. DOI: 10.1093/jxb/ery024 ; PMID: 29444316
- Glucose Uptake via STP Transporters Inhibits in Vitro Pollen Tube Growth in a HEXOKINASE1-Dependent Manner in Arabidopsis thaliana. DOI: 10.1105/tpc.18.00356 ; PMID: 30120167
- The role of HEXOKINASE1 in Arabidopsis leaf growth. DOI: 10.1007/s11103-018-0803-0 ; PMID: 30511331
- Cytosolic Invertase-Mediated Root Growth Is Feedback Regulated by a Glucose-Dependent Signaling Loop. DOI: 10.1104/pp.20.00778 ; PMID: 32820066
- Tuning self-renewal in the Arabidopsis stomatal lineage by hormone and nutrient regulation of asymmetric cell division. DOI: 10.7554/eLife.63335 ; PMID: 33739283
- HEXOKINASE1 signalling promotes shoot branching and interacts with cytokinin and strigolactone pathways. DOI: 10.1111/nph.17427 ; PMID: 33909299
- Sugar inhibits brassinosteroid signaling by enhancing BIN2 phosphorylation of BZR1. DOI: 10.1371/journal.pgen.1009540 ; PMID: 33989283
- Guard cells control hypocotyl elongation through HXK1, HY5, and PIF4. DOI: 10.1038/s42003-021-02283-y ; PMID: 34155329
- and sucrose-signaling modules regulate the Arabidopsis juvenile-to-adult phase transition. DOI: 10.1016/j.celrep.2021.109348 ; PMID: 34260932
- Interactome of Arabidopsis Thaliana. DOI: 10.3390/plants11030350 ; PMID: 35161331
- HEXOKINASE1 forms a nuclear complex with the PRC2 subunits CURLY LEAF and SWINGER to regulate glucose signaling. DOI: 10.1111/jipb.13261 ; PMID: 35394700
- Long-distance transport of sucrose in source leaves promotes sink root growth by the EIN3-SUC2 module. DOI: 10.1371/journal.pgen.1010424 ; PMID: 36129930
- Guard cell activity of PIF4 and HY5 control transpiration. DOI: 10.1016/j.plantsci.2022.111583 ; PMID: 36608874
- Arabidopsis ACT DOMAIN REPEAT9 represses glucose signaling pathways. DOI: 10.1093/plphys/kiad127 ; PMID: 36843191
- Sugar status in preexisting leaves determines systemic stomatal development within newly developing leaves. DOI: 10.1073/pnas.2302854120 ; PMID: 37276396
- The class VIII myosin ATM1 is required for root apical meristem function. DOI: 10.1242/dev.201762 ; PMID: 37306290
- Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. DOI: 10.1105/tpc.016055 ; PMID: 14671022
- The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. DOI: 10.1105/tpc.104.027078 ; PMID: 15539469
- Mapping the Arabidopsis organelle proteome. DOI: 10.1073/pnas.0506958103 ; PMID: 16618929
- A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. DOI: 10.1074/mcp.M600250-MCP200 ; PMID: 17151019
- Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques. DOI: 10.1021/pr060525b ; PMID: 17432890
Gene Resources
- UniProt: Q0WLE0
- EMBL: AK230265
- AlphaFoldDB: Q0WLE0
- EnsemblPlants: AT4G29130.1
- Gramene: AT4G29130.1
- KEGG: ath:AT4G29130
- Orthologous matrix: GYCFSYP
- ExpressionAtlas: AT4G29130
- InterPro: IPR001312, IPR019807, IPR022672
- PANTHER: PTHR19443, PTHR19443:SF16
- SUPFAM: SSF53067
- PROSITE: PS00378, PS51748
- Gene3D: 3.30.420.40, 3.40.367.20
- OrthoDB: Q0WLE0
- SWISS-MODEL: Q0WLE0
- Conserved Domain Database: cd24020
Sequences
cDNA Sequence
- >AT4G29130.1
AAAACCGAAATTAGACAAAAGGTTAATTTCGTCATTTCAACAGATTCTATTACCACTTCTTGTTTTGTTTTTCCATACTTTACGGACAAGAACGAGAGAAGCTCTCGCTTACGTGGTTTCTACACTGTTTTTGACGAACCCACCAAGCTCGAGTAGATCGGTATTAGATCCATCTTAGGTTTCTCTAATTTCTCTCAATTCACTCCAAAATTTTGATTATTTCTTCTTTCTGGCTTGTCAATTTTAGTCATTTGTAATCCTTGCTTTTGCGATCGGAATCGTAAAAATCCGATCTTTCTTTTAGATTCGTTTTGTTTTTGATTCCAAATCGGAAAAATGGGTAAAGTAGCTGTTGGAGCGACTGTTGTTTGCACGGCGGCGGTTTGTGCGGTGGCTGTTTTGGTTGTTCGACGACGGATGCAGAGCTCAGGGAAGTGGGGACGTGTTTTGGCTATCCTCAAGGCCTTTGAAGAGGATTGTGCGACTCCGATCTCGAAACTGAGACAAGTGGCTGATGCTATGACCGTTGAGATGCATGCTGGTCTTGCATCCGACGGTGGTAGCAAACTCAAGATGCTTATCAGCTACGTTGATAATCTTCCTTCCGGGGATGAAAAGGGTCTCTTTTATGCATTGGACCTAGGGGGGACAAACTTCCGTGTCATGCGTGTGCTTCTTGGCGGGAAGCAAGAGCGTGTTGTTAAACAAGAATTCGAAGAAGTTTCGATTCCTCCTCATTTGATGACTGGTGGTTCAGATGAGTTGTTCAATTTTATAGCTGAAGCTCTTGCGAAGTTTGTCGCTACAGAATGCGAAGACTTTCATCTTCCAGAAGGTAGACAGAGGGAATTAGGTTTCACTTTCTCGTTTCCTGTTAAGCAGACTTCTCTGTCCTCTGGTAGTCTCATCAAATGGACAAAAGGCTTTTCCATCGAAGAAGCAGTTGGACAAGATGTTGTTGGAGCACTTAATAAGGCTCTGGAAAGAGTTGGTCTTGACATGCGAATCGCAGCACTTGTTAATGATACCGTTGGAACACTAGCCGGTGGTAGATACTATAACCCGGATGTTGTTGCTGCTGTTATTTTAGGCACTGGGACAAACGCAGCCTATGTTGAGCGTGCAACCGCGATCCCTAAATGGCATGGTCTGCTTCCAAAATCAGGAGAAATGGTTATAAACATGGAATGGGGAAACTTCAGGTCATCACATCTTCCATTAACCGAGTTTGATCACACGCTGGATTTCGAGAGTCTGAATCCAGGCGAACAGATTCTTGAGAAAATCATTTCCGGTATGTACTTGGGAGAGATTTTGCGAAGAGTTCTTCTAAAGATGGCTGAAGATGCTGCTTTCTTTGGCGATACAGTCCCATCTAAGCTGAGAATACCATTCATCATTAGGACTCCTCACATGTCGGCTATGCACAACGACACTTCTCCAGACTTGAAGATTGTTGGGAGCAAGATTAAGGATATATTGGAGGTCCCTACAACTTCTCTGAAAATGAGAAAAGTTGTGATCAGTCTCTGCAACATCATAGCAACCCGAGGAGCTCGTCTCTCTGCTGCTGGAATCTATGGTATTCTGAAGAAACTGGGAAGAGATACTACTAAAGACGAGGAGGTGCAGAAATCGGTTATAGCCATGGATGGTGGATTGTTTGAGCATTACACTCAGTTTAGTGAGTGTATGGAGAGCTCACTAAAAGAGTTGCTTGGAGATGAAGCTTCAGGAAGCGTTGAAGTCACTCACTCCAATGATGGATCAGGCATTGGAGCTGCGCTTCTTGCTGCTTCTCACTCTCTCTACCTTGAAGACTCTTAAAACCTACCCAAAGAGCGCCATTTTTCGGTAATTTACTGAAAGCTTTTCGCTATCAGAAAACGCCTAAGCCAAGTTCTAAGGCGTCATAAAAGAAAGCATTCCATGTTTTTACTCTTCCCCAAGACTTTCTTTGTAGCAAATAAGTTTCCTTGGGAGAAATATTTGTTTTCATGTTCTTCAAAAATAAAAGACTCAGTTCTTCAGATTCTGGGATTTTATTATAACCAGATATGTTGTAAAAACTACAAATTCAAAGCTCACTTCACTGGAGTTCTGAGTATATAAAGATTTCATTTTTCCT
CDS Sequence
Protein Sequence