Gene Details:

• Gene ID: AT4G26430
• Gene Symbol: CSN6B
• Gene Name: COP9 signalosome subunit 6B
• Description: COP9 signalosome subunit 6B;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G26430.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Germplasm Phenotype:

• csn6a-1 csn6b-1  — In the dark and under all light conditions tested, loss of function for both CSN6 proteins (double homozygous progeny) results in lethality at the seedling stage and in a photomorphogenic phenotype indistinguishable from the fusca-type phenotype of the null cop/det/fus mutants described for the other CSN subunits.
• csn6a-1 csn6b-1  — In the double homozygous progeny, significant reduction of CSN1, CSN3, CSN4, CSN7, and CSN8. The only subunits not affected are CSN2 and CSN5.
• csn6a-1 csn6b-1  — In the homozygous progeny, anthocyanin accumulation (purple coloration) in the cotelydons of developing embryos.
• csn6a-1 csn6b-1  — Mutation is lethal in the homozygous state.
• csn6b-1  — Mutants display a mild partial photomorphogenic phenotype in the dark and in blue light, characterized by shorter hypocotyls with respect to wildtype plants grown under the same conditions.
• csn6b-1  — No detectable changes in the cellular pools of COP9 signalosome complex subunits.
• csn6b-1  — The mutant do not display any obvious morphological defects in white light and after the seedling stage.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure

Literature:

• The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.   DOI:  10.1016/s0960-9822(07)00372-7 ;  PMID:  9707402
• Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis.   DOI:  10.1105/tpc.010248 ;  PMID:  11701877
• Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome.   DOI:  10.1093/emboj/20.24.7096 ;  PMID:  11742986
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases.   DOI:  10.1105/tpc.106.047571 ;  PMID:  17307927
• The COP9 signalosome subunit 6 (CSN6): a potential oncogene.   DOI:  10.1186/1747-1028-8-14 ;  PMID:  24286178
• Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases.   DOI:  10.1105/tpc.106.047571 ;  PMID:  17307927

Sequences: