Gene Details:

• Gene ID: AT4G25110
• Gene Symbol: AtMC2, AtMCP1c, MC2, MCP1c
• Gene Name: metacaspase 2, metacaspase 1c, metacaspase 2, metacaspase 1c
• Description: metacaspase 2;(source:Araport11)
• TAIR Accession: locus:2117288
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G25110.1     AT4G25110.2

Plant Ontology Annotations:

• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Gene Ontology:

• GO:0043069  — acts upstream of or within — negative regulation of programmed cell death
• GO:0004197  — enables — cysteine-type endopeptidase activity
• GO:0006508  — involved in — proteolysis
• GO:0005737  — is active in — cytoplasm

Germplasm Phenotype:

• CS68733  — No visible phenotype.
• CS68735  — Strong salicylic acid-induced cell death.
• CS68736  — No visible phenotype.
• CS68737  — No visible phenotype.

Function-related keywords:

• vascular leaf ,  stamen ,  cotyledon ,  collective leaf structure

Literature:

• Antagonistic control of oxidative stress-induced cell death in Arabidopsis by two related, plant-specific zinc finger proteins.   DOI:  10.1073/pnas.1130421100 ;  PMID:  12732715
• Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine.   DOI:  10.1074/jbc.M406329200 ;  PMID:  15326173
• Oviposition by pierid butterflies triggers defense responses in Arabidopsis.   DOI:  10.1104/pp.106.090837 ;  PMID:  17142483
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Arabidopsis type I metacaspases control cell death.   DOI:  10.1126/science.1194980 ;  PMID:  21097903
• Recent advance in the study of caspase-like proteases and Bax inhibitor-1 in plants: their possible roles as regulator of programmed cell death.   DOI:  10.1111/j.1364-3703.2004.00206.x ;  PMID:  20565583
• Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress.   DOI:  10.1093/plphys/kiab335 ;  PMID:  34618053
• Evolutionary Diversity and Function of Metacaspases in Plants: Similar to but Not Caspases.   DOI:  10.3390/ijms23094588 ;  PMID:  35562978

Sequences: