Gene Details:
- Gene ID: AT4G23850
- Gene Symbol: LACS4
- Gene Name: long-chain acyl-CoA synthetase 4
- Description:
- TAIR Accession: locus:2138141
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0000293 — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)
Gene Ontology:
- GO:0004467 — enables — long-chain fatty acid-CoA ligase activity
- GO:0006633 — acts upstream of or within — fatty acid biosynthetic process
- GO:0005794 — located in — Golgi apparatus
- GO:0005634 — located in — nucleus
- GO:0006631 — involved in — fatty acid metabolic process
- GO:0009684 — acts upstream of — indoleacetic acid biosynthetic process
- GO:0080024 — involved in — indolebutyric acid metabolic process
- GO:0005783 — is active in — endoplasmic reticulum
- GO:0016020 — is active in — membrane
- GO:0005777 — colocalizes with — peroxisome
Function-related keywords:
- shoot axis apex , leaf lamina base , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , guard cell
Literature:
- Brassica napus cDNAs encoding fatty acyl-CoA synthetase. DOI: 10.1023/a:1005780529307 ; PMID: 9106514
- Arabidopsis contains nine long-chain acyl-coenzyme a synthetase genes that participate in fatty acid and glycerolipid metabolism. DOI: 10.1104/pp.003269 ; PMID: 12177484
- Cell cycle-regulated gene expression in Arabidopsis. DOI: 10.1074/jbc.M207570200 ; PMID: 12169696
- Two long-chain acyl-CoA synthetases from Arabidopsis thaliana involved in peroxisomal fatty acid beta-oxidation. DOI: 10.1046/j.1365-313x.2002.01405.x ; PMID: 12366803
- Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme a synthetases. DOI: 10.1104/pp.103.020552 ; PMID: 12805634
- Systemic gene expression in Arabidopsis during an incompatible interaction with Alternaria brassicicola. DOI: 10.1104/pp.103.021683 ; PMID: 12805628
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Insertional mutant analysis reveals that long-chain acyl-CoA synthetase 1 (LACS1), but not LACS8, functionally overlaps with LACS9 in Arabidopsis seed oil biosynthesis. DOI: 10.1111/j.1365-313X.2010.04396.x ; PMID: 21143684
- Combined activity of LACS1 and LACS4 is required for proper pollen coat formation in Arabidopsis. DOI: 10.1111/j.1365-313X.2011.04722.x ; PMID: 21790813
- Acyl-lipid metabolism. DOI: 10.1199/tab.0161 ; PMID: 23505340
- Two activities of long-chain acyl-coenzyme A synthetase are involved in lipid trafficking between the endoplasmic reticulum and the plastid in Arabidopsis. DOI: 10.1104/pp.114.250365 ; PMID: 25540329
- Functional Overlap of Long-Chain Acyl-CoA Synthetases in Arabidopsis. DOI: 10.1093/pcp/pcz019 ; PMID: 30715495
- Brassica napus cDNAs encoding fatty acyl-CoA synthetase. DOI: 10.1023/a:1005780529307 ; PMID: 9106514
- Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. DOI: 10.1074/mcp.M600429-MCP200 ; PMID: 17317660
- Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. DOI: 10.1021/pr1009433 ; PMID: 21166475
Sequences:
cDNA Sequence
- >AT4G23850.1
TTCAGGTTTATGGTCAGTGAGTAGCAACCAATCGCAGTCGTAGTTGAAAGTCTCTATTAACTTCTTCTCCGATCTGAGAAAACGCGTCAGAAGTTTCTCGTTCTACAGATAGAGAGAGAAGAGAACGAGAACGAAGTAGAGAGAGAGAGAGAGAGATCATGTCGCAGCAGAAGAAATACATCTTCCAAGTTGAAGAAGGCAAAGAAGGTAGCGATGGAAGACCATCAGTTGGTCCAGTGTACCGGAGTATCTTTGCCAAGGACGGATTTCCCGACCCGATCGAAGGAATGGATAGTTGTTGGGATGTTTTCCGCATGTCTGTTGAGAAGTATCCAAACAATCCAATGCTGGGACGCCGCGAGATTGTAGATGGAAAGCCGGGTAAGTATGTCTGGCAAACATACCAAGAAGTCTACGACATTGTCATGAAACTTGGAAATTCTCTCAGAAGTGTTGGAGTTAAGGACGAAGCAAAATGTGGTATCTATGGTGCAAATTCTCCTGAGTGGATTATCAGCATGGAGGCTTGTAATGCACATGGACTCTATTGTGTACCGTTATATGATACACTAGGTGCTGATGCTGTGGAATTCATCATTTCCCATTCAGAGGTTTCAATTGTCTTTGTGGAAGAGAAGAAGATCTCTGAGTTGTTCAAGACATGCCCAAACTCGACAGAGTACATGAAAACTGTTGTGAGCTTCGGGGGTGTCTCACGTGAACAAAAAGAAGAAGCTGAAACTTTTGGGTTGGTTATATATGCTTGGGATGAATTTTTGAAGCTGGGTGAAGGAAAGCAATATGATCTCCCAATCAAAAAGAAAAGCGACATTTGCACGATTATGTATACGAGTGGAACCACTGGTGACCCAAAGGGAGTGATGATATCTAACGAAAGCATTGTGACTCTAATCGCTGGAGTGATCCGTCTACTGAAAAGTGCTAACGAGGCTCTGACTGTGAAAGATGTGTATCTTTCTTATCTTCCTCTTGCCCACATCTTTGACCGAGTTATCGAGGAGTGTTTCATTCAACATGGTGCTGCAATTGGCTTCTGGCGAGGGGATGTAAAATTGTTGATCGAAGACCTTGCTGAGCTTAAACCAACTATTTTTTGTGCTGTACCTCGTGTCCTGGATAGAGTATACTCAGGTCTTCAGAAGAAGCTTTCTGATGGTGGATTCTTAAAAAAGTTCATATTTGATTCTGCATTTTCCTATAAATTTGGTTATATGAAGAAGGGACAGTCTCATGTGGAGGCCTCTCCACTTTTTGACAAACTTGTGTTCAGCAAGGTTAAACAAGGACTCGGAGGCAATGTGAGGATTATTCTATCTGGAGCTGCTCCTCTTGCTAGTCACGTAGAGTCATTTCTAAGAGTGGTGGCATGCTGTCATGTTCTCCAAGGATACGGTCTTACTGAAAGCTGTGCTGGAACTTTTGTCTCGCTGCCAGATGAACTAGGTATGCTCGGCACAGTTGGTCCACCAGTGCCAAACGTTGATATACGCCTTGAATCCGTCCCCGAGATGGAATATGATGCTCTTGCGAGTACTGCACGTGGTGAAATCTGCATTCGGGGAAAGACCCTTTTCTCTGGTTACTACAAACGTGAAGATCTCACGAAAGAGGTTCTCATTGATGGATGGCTGCACACAGGTGATGTTGGTGAGTGGCAACCAGATGGAAGCATGAAGATAATTGACAGGAAGAAGAATATCTTTAAACTCTCACAAGGAGAGTATGTTGCGGTGGAGAACATAGAAAACATATACGGTGAAGTACAAGCTGTTGATTCCGTGTGGGTGTACGGTAACAGCTTTGAGTCCTTCCTAATAGCTATCGCCAACCCAAACCAGCATATCCTTGAACGCTGGGCTGCAGAAAACGGTGTGAGTGGTGACTATGACGCTCTCTGTCAAAATGAAAAGGCAAAGGAATTCATTCTCGGAGAACTTGTTAAAATGGCCAAAGAGAAAAAGATGAAAGGGTTCGAGATCATCAAGGCGATTCATCTTGACCCAGTGCCATTTGACATGGAACGAGATCTTCTTACGCCGACCTTCAAAAAGAAAAGGCCTCAGTTGCTGAAATACTACCAGAGTGTGATCGACGAAATGTACAAGACCATAAATGCAAAATTTGCTTCCAGAGGGTAGATTCCTCCTCACTCTCGGTCCTTGGGTCTCTCATTTTGCATGACGAAGACTTTGTTAATAGGCTCTTCTCTCATCTGTGTACAATATTTGAATATTTCATAGCATCAGATCAGTCCAGAGCTGCTACACTGTTTTTCTTTTCTATCTTTTTTTGGAAATTTACTTTTATGTTCTATACTTGAATGCTATCTCTTTGCCAAAAAAAAAAAAAAAGAATGCTATCTAACTTTTCTTTTTAATAAAATTTTAAAATACATGGCGCTGTC
CDS Sequence
Protein Sequence