Gene Details:
- Gene ID: AT4G23650
- Gene Symbol: AtCDPK6, CDPK6, CPK3
- Gene Name: calcium-dependent protein kinase 6, Calcium dependent protein kinase 3
- Description: calcium-dependent protein kinase 6;(source:Araport11)
- TAIR Accession: locus:2128409
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0000293 — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)
- PO:0004006 — mesophyll cell — célula del mesófilo (Spanish, exact), 葉肉細胞 (Japanese, exact)
Gene Ontology:
- GO:0004683 — enables — calmodulin-dependent protein kinase activity
- GO:0006499 — has protein modification of type — N-terminal protein myristoylation
- GO:0009931 — enables — calcium-dependent protein serine/threonine kinase activity
- GO:0018105 — involved in — peptidyl-serine phosphorylation
- GO:0005634 — is active in — nucleus
- GO:0004674 — enables — protein serine/threonine kinase activity
- GO:0005515 — enables — protein binding
- GO:0009738 — acts upstream of or within — abscisic acid-activated signaling pathway
- GO:0005886 — located in — plasma membrane
- GO:0005509 — enables — calcium ion binding
- GO:0010119 — acts upstream of or within — regulation of stomatal movement
- GO:0000325 — located in — plant-type vacuole
- GO:0016020 — located in — membrane
- GO:0004672 — enables — protein kinase activity
- GO:0046777 — acts upstream of or within — protein autophosphorylation
- GO:0005516 — enables — calmodulin binding
- GO:0005737 — is active in — cytoplasm
- GO:0009651 — acts upstream of or within — response to salt stress
- GO:0046777 — involved in — protein autophosphorylation
- GO:0009507 — located in — chloroplast
- GO:0035556 — involved in — intracellular signal transduction
- GO:0005829 — located in — cytosol
Function-related keywords:
- shoot axis apex , leaf lamina base , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , guard cell , mesophyll cell , guard cell
Literature:
- Purification of a nitrate reductase kinase from Spinacea oleracea leaves, and its identification as a calmodulin-domain protein kinase. DOI: 10.1007/s004250050419 ; PMID: 9763711
- Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family. DOI: 10.1104/pp.005645 ; PMID: 12068094
- Analysis of EF-hand-containing proteins in Arabidopsis. DOI: 10.1186/gb-2002-3-10-research0056 ; PMID: 12372144
- Transcriptome changes for Arabidopsis in response to salt, osmotic, and cold stress. DOI: 10.1104/pp.008532 ; PMID: 12481097
- The Arabidopsis CDPK-SnRK superfamily of protein kinases. DOI: 10.1104/pp.102.011999 ; PMID: 12805596
- Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. DOI: 10.1074/jbc.M307321200 ; PMID: 12912986
- Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. DOI: 10.1074/jbc.M308435200 ; PMID: 14576160
- Calcium/calmodulin-mediated signal network in plants. DOI: 10.1016/j.tplants.2003.09.004 ; PMID: 14557048
- Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. DOI: 10.1101/gr.2544504 ; PMID: 15489341
- Retrograde plastid redox signals in the expression of nuclear genes for chloroplast proteins of Arabidopsis thaliana. DOI: 10.1074/jbc.M406358200 ; PMID: 15561727
- A quantitative analysis of Arabidopsis plasma membrane using trypsin-catalyzed (18)O labeling. DOI: 10.1074/mcp.M500414-MCP200 ; PMID: 16635983
- Mapping the Arabidopsis organelle proteome. DOI: 10.1073/pnas.0506958103 ; PMID: 16618929
- and Ca(2+)-permeable channels and stomatal closure. DOI: 10.1371/journal.pbio.0040327 ; PMID: 17032064
- Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. DOI: 10.1073/pnas.0611615104 ; PMID: 17360592
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling. DOI: 10.1186/1471-2229-10-97 ; PMID: 20504319
- The Ca(2+) -dependent protein kinase CPK3 is required for MAPK-independent salt-stress acclimation in Arabidopsis. DOI: 10.1111/j.1365-313X.2010.04257.x ; PMID: 20497378
- Kinetic analysis of 14-3-3-inhibited Arabidopsis thaliana nitrate reductase. DOI: 10.1021/bi1003487 ; PMID: 20690630
- The Arabidopsis calcium-dependent protein kinase, CPK6, functions as a positive regulator of methyl jasmonate signaling in guard cells. DOI: 10.1104/pp.110.162750 ; PMID: 20978156
- Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. DOI: 10.1016/j.phytochem.2011.02.029 ; PMID: 21477822
- Characterization of Arabidopsis calcium-dependent protein kinases: activated or not by calcium? DOI: 10.1042/BJ20112072 ; PMID: 22827269
- Screening for in planta protein-protein interactions combining bimolecular fluorescence complementation with flow cytometry. DOI: 10.1186/1746-4811-8-25 ; PMID: 22789293
- CPK3-phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells. DOI: 10.1093/jxb/ert171 ; PMID: 23846874
- Light modulated activity of root alkaline/neutral invertase involves the interaction with 14-3-3 proteins. DOI: 10.1111/tpj.12677 ; PMID: 25256212
- Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement. DOI: 10.3389/fchem.2017.00115 ; PMID: 29312925
- Glucose triggers stomatal closure mediated by basal signaling through HXK1 and PYR/RCAR receptors in Arabidopsis. DOI: 10.1093/jxb/ery024 ; PMID: 29444316
- N-myristoylation and S-acylation are common modifications of Ca(2+) -regulated Arabidopsis kinases and are required for activation of the SLAC1 anion channel. DOI: 10.1111/nph.15053 ; PMID: 29498046
- Abscisic acid-induced degradation of Arabidopsis guanine nucleotide exchange factor requires calcium-dependent protein kinases. DOI: 10.1073/pnas.1719659115 ; PMID: 29686103
- The Arabidopsis Calcium-Dependent Protein Kinases (CDPKs) and Their Roles in Plant Growth Regulation and Abiotic Stress Responses. DOI: 10.3390/ijms19071900 ; PMID: 29958430
- Guard Cell Salicylic Acid Signaling Is Integrated into Abscisic Acid Signaling via the Ca(2+)/CPK-Dependent Pathway. DOI: 10.1104/pp.18.00321 ; PMID: 30037808
- The Receptor-like Pseudokinase GHR1 Is Required for Stomatal Closure. DOI: 10.1105/tpc.18.00441 ; PMID: 30361234
- REM1.3's phospho-status defines its plasma membrane nanodomain organization and activity in restricting PVX cell-to-cell movement. DOI: 10.1371/journal.ppat.1007378 ; PMID: 30419072
- Global Quantitative Proteomics Studies Revealed Tissue-Preferential Expression and Phosphorylation of Regulatory Proteins in Arabidopsis. DOI: 10.3390/ijms21176116 ; PMID: 32854314
- Raf-like kinases and receptor-like (pseudo)kinase GHR1 are required for stomatal vapor pressure difference response. DOI: 10.1073/pnas.2107280118 ; PMID: 34799443
- Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. DOI: 10.1074/jbc.M307321200 ; PMID: 12912986
- The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. DOI: 10.1105/tpc.104.027078 ; PMID: 15539469
- Mapping the Arabidopsis organelle proteome. DOI: 10.1073/pnas.0506958103 ; PMID: 16618929
- Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. DOI: 10.1074/mcp.M600429-MCP200 ; PMID: 17317660
- Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement. DOI: 10.3389/fchem.2017.00115 ; PMID: 29312925
Sequences:
cDNA Sequence
- >AT4G23650.1
TAGCCGTGTGATTGATTGGAGAAGTGGAAACAACTAATATGCAGAAGATTTCCACATCCACTAATTTATCTTCCAATGGGACAAATACTTTTGTTTATACGCGGTTCAACTACGTACCAATAAAAACACGCCACGTGGTCATCGTGTCTGATCTCAGACATTAAAAAGCCATAAGAATCGGAGATACAATCTTTCTCTCTCGATTGACTTTATTGACTGAGAGAAAGCTTTTGACAATGGGCCACAGACACAGCAAGTCCAAATCCTCCGATCCGCCACCGTCCTCCTCCTCCTCTTCCTCCGGCAACGTAGTCCACCATGTTAAACCTGCCGGAGAACGCCGCGGATCATCCGGTTCCGGAACCGTCGGATCGTCAGGCTCCGGAACAGGCGGATCTCGTTCCACCACATCTACTCAGCAGAATGGTCGGATCTTAGGTCGGCCGATGGAGGAAGTACGGAGAACCTATGAGTTTGGTCGTGAGCTTGGTCGTGGCCAGTTTGGTGTCACGTACCTCGTAACTCACAAAGAGACGAAACAACAGGTCGCTTGCAAGTCAATCCCTACGCGCCGCCTTGTTCACAAAGACGACATTGAAGATGTTCGCCGTGAAGTCCAGATTATGCACCATCTCAGCGGTCACCGGAACATAGTGGACTTGAAGGGAGCCTACGAGGACAGACACTCTGTGAATCTGATAATGGAGTTGTGTGAAGGAGGGGAATTGTTCGATAGGATCATTTCTAAAGGTCTTTACTCAGAGAGAGCTGCTGCGGATTTGTGTAGGCAGATGGTGATGGTTGTGCATAGTTGTCATTCTATGGGTGTAATGCACCGAGACTTGAAGCCCGAAAACTTTCTCTTTCTTAGTAAAGATGAGAACTCACCATTGAAAGCTACAGACTTTGGTCTCTCTGTCTTCTTCAAGCCAGGTGATAAGTTTAAGGATCTTGTTGGAAGTGCATACTATGTTGCCCCAGAAGTTCTAAAACGGAACTATGGACCAGAGGCTGATATCTGGAGTGCTGGTGTGATTCTATACATCCTTCTCAGTGGTGTTCCGCCTTTCTGGGGAGAAAATGAAACGGGGATCTTTGATGCCATTCTTCAAGGGCAACTTGATTTTTCAGCTGATCCATGGCCAGCACTATCAGATGGTGCCAAAGATCTTGTGAGGAAAATGTTAAAATATGACCCTAAAGATCGGCTTACAGCTGCGGAAGTGCTAAATCATCCGTGGATTAGAGAAGATGGGGAGGCATCAGACAAACCGCTTGACAATGCGGTGTTATCCAGGATGAAACAATTCCGGGCGATGAACAAACTAAAAAAAATGGCCCTGAAGGTTATCGCTGAGAACCTTTCTGAAGAAGAAATCATTGGTCTTAAAGAGATGTTCAAATCTCTAGACACTGATAACAATGGAATAGTCACCTTGGAGGAATTGAGAACCGGTCTCCCAAAACTTGGTTCAAAGATCTCTGAAGCTGAAATAAGGCAGTTAATGGAAGCAGCTGATATGGATGGAGATGGATCAATTGATTACTTGGAGTTTATATCAGCCACAATGCATATGAACAGAATCGAACGTGAGGATCACTTGTACACCGCATTCCAGTTCTTTGACAATGACAACAGCGGCTACATAACAATGGAAGAGCTAGAGCTAGCCATGAAGAAATACAACATGGGTGATGATAAATCCATCAAAGAGATCATTGCTGAAGTAGACACCGATCGTGACGGAAAAATCAACTACGAAGAATTTGTAGCGATGATGAAGAAGGGAAATCCAGAATTGGTGCCAAACCGACGCAGAATGTGAGAGATCTTTTGATGTTGTTTGTTTGTTTTTGGTTATCACTTTACTCAAACTTTGTGTTTCTGTTACAATCAATTATTTTGTTTCCTGCAATCTCTTTTTATCAACACAACATAAAAAATACTTTGAGATCAGAAAGCCATTTGCAGGTTTGGTTAATGACTTATGAGAGATTCAATATATAATAATTACAGGTTGATTCTTGCATGATT
CDS Sequence
Protein Sequence