Gene Details:
- Gene ID: AT4G21070
- Gene Symbol: ATBRCA1, BRCA1
- Gene Name: ARABIDOPSIS THALIANA BREAST CANCER SUSCEPTIBILITY1, breast cancer susceptibility1
- Description: breast cancer susceptibility1;(source:Araport11)
- TAIR Accession:
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000003 — whole plant — planta entera (Spanish, exact), 植物体全体 (Japanese, exact), clonal colony (related), colony (related), bush (narrow), frutex (narrow), frutices (narrow), gametophyte (narrow), herb (narrow), liana (narrow), prothalli (narrow), prothallium (narrow), prothallus (narrow), seedling (narrow), shrub (narrow), sporophyte (narrow), suffrutex (narrow), suffrutices (narrow), tree (narrow), vine (narrow), woody clump (narrow), genet (broad), ramet (broad)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
Function-related keywords:
Literature:
- Cell cycle-regulated gene expression in Arabidopsis. DOI: 10.1074/jbc.M207570200 ; PMID: 12169696
- Evaluation and classification of RING-finger domains encoded by the Arabidopsis genome. DOI: 10.1186/gb-2002-3-4-research0016 ; PMID: 11983057
- Transcriptional profiling of Arabidopsis tissues reveals the unique characteristics of the pollen transcriptome. DOI: 10.1104/pp.103.028241 ; PMID: 14500793
- Arabidopsis DNA double-strand break repair pathways. DOI: 10.1042/BST0320964 ; PMID: 15506937
- Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis. DOI: 10.1104/pp.104.052423 ; PMID: 15644464
- A homologue of the breast cancer-associated gene BARD1 is involved in DNA repair in plants. DOI: 10.1038/sj.emboj.7601313 ; PMID: 16957774
- ATR and ATM play both distinct and additive roles in response to ionizing radiation. DOI: 10.1111/j.1365-313X.2006.02931.x ; PMID: 17227549
- E2F regulates FASCIATA1, a chromatin assembly gene whose loss switches on the endocycle and activates gene expression by changing the epigenetic status. DOI: 10.1104/pp.106.094979 ; PMID: 17351056
- The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability. DOI: 10.1242/dev.020743 ; PMID: 18434413
- Mutation of Arabidopsis BARD1 causes meristem defects by failing to confine WUSCHEL expression to the organizing center. DOI: 10.1105/tpc.108.058867 ; PMID: 18591352
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- BARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL1. DOI: 10.4161/psb.4.1.7312 ; PMID: 19704708
- BRCC36A is epistatic to BRCA1 in DNA crosslink repair and homologous recombination in Arabidopsis thaliana. DOI: 10.1093/nar/gkq722 ; PMID: 20817926
- Homologs of breast cancer genes in plants. DOI: 10.3389/fpls.2011.00019 ; PMID: 22629260
- Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response. DOI: 10.1105/tpc.15.00172 ; PMID: 26320227
- DNA Damage-Induced Transcription of Transposable Elements and Long Non-coding RNAs in Arabidopsis Is Rare and ATM-Dependent. DOI: 10.1016/j.molp.2016.04.015 ; PMID: 27150037
- Analysis of the Relationships between DNA Double-Strand Breaks, Synaptonemal Complex and Crossovers Using the Atfas1-4 Mutant. DOI: 10.1371/journal.pgen.1005301 ; PMID: 26147458
- Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana. DOI: 10.1371/journal.pgen.1006092 ; PMID: 27253878
- Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis. DOI: 10.1104/pp.17.00031 ; PMID: 28153919
- Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control. DOI: 10.15252/embj.201694561 ; PMID: 28320736
- Cell cycle arrest mediated by Cd-induced DNA damage in Arabidopsis root tips. DOI: 10.1016/j.ecoenv.2017.07.074 ; PMID: 28800532
- Transcriptome-based biological dosimetry of gamma radiation in Arabidopsis using DNA damage response genes. DOI: 10.1016/j.jenvrad.2017.11.007 ; PMID: 29128690
- Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots. DOI: 10.1016/j.chemosphere.2018.03.017 ; PMID: 29533809
- APURINIC/APYRIMIDINIC ENDONUCLEASE2 and ZINC FINGER DNA 3'-PHOSPHOESTERASE Play Overlapping Roles in the Maintenance of Epigenome and Genome Stability. DOI: 10.1105/tpc.18.00287 ; PMID: 30135084
- SOG1-dependent NAC103 modulates the DNA damage response as a transcriptional regulator in Arabidopsis. DOI: 10.1111/tpj.14201 ; PMID: 30554433
- Selective autophagy regulates heat stress memory in Arabidopsis by NBR1-mediated targeting of HSP90.1 and ROF1. DOI: 10.1080/15548627.2020.1820778 ; PMID: 32967551
- Detection of Genes in Arabidopsis thaliana L. Responding to DNA Damage from Radiation and Other Stressors in Spaceflight. DOI: 10.3390/genes12060938 ; PMID: 34205326
- The multi-BRCT domain protein DDRM2 promotes the recruitment of RAD51 to DNA damage sites to facilitate homologous recombination. DOI: 10.1111/nph.18787 ; PMID: 36727295
- Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis. DOI: 10.1104/pp.104.052423 ; PMID: 15644464
- Repertoire of plant RING E3 ubiquitin ligases revisited: New groups counting gene families and single genes. DOI: 10.1371/journal.pone.0203442 ; PMID: 30169501
Sequences:
cDNA Sequence
- >AT4G21070.1
CGGGATTGGAAATATTTTGAAGTAGATGAAAATTTGGCGCTTTTTATTTAGTCTGTAAAGCTTTCAAGGGAAGCCTCTTTGAAGGACACGCTTCGTCATCTATCTATCTATATACCCAAAGAGTCGCTTTGTTCCTGATTCATCAGATTGATTCGTTTCGTTTTCTCTGAGTGAAGATCGAAAATGGCGGACACTAGTCACCTGGAGAGGATGGGAAGAGAACTCAAGTGCCCTATTTGCTTGAGTCTATATAATTCTGCAGTTTCACTTTCGTGTAACCATGTATTTTGCAATGCGTGTATAGTGAAATCTATGAAAATGGATGCTACTTGTCCTGTTTGTAAAATCCCTTACCATCGTAGAGAGATTCGAGGTGCTCCACATATGGATAGCTTGGTGAGCATTTACAAGAACATGGAAGATGCTTCTGGGATTAAATTATTCGTTAGCCAGAATAATCCGTCACCATCAGATAAAGAAAAGCAAGTAAGAGATGCTTCCGTTGAAAAGGCAAGTGATAAGAATCGTCAGGGATCTAGGAAGGGCCGAGCATCCAAGAGGAACGAGTATGGGAAAACCAAGGAAATAGATGTAGATGCACCTGGGCCTATTGTTATGAAACCTTCATCCCAAACCAAGAAGAGGGTGCAGCTGCTCCAGAATCTGTCTGCTGAAAGTTTAACTAAACCTACTGAGTCTGTTGAAACAGCTGAAAAACCCAAGGACTACACTGAAAACACTGTGATTCGTTTGGATGAGCATCCATCTCTGAATAAAGAAGGAAATCTTTCACCCTTCTTTTGGTTGAGAGATGAAGATGATGGGGAGAACTCAAGTCAGCGTACAGAAAGTGATCAACTTTTAGGGACTACACCAGTTAATGTTCCCTCTTTCAGCGATTTGATGGACTCAGATCATGAGAGCCCATCGAAGGAAGACGAGCAACAAAAGCCCAATCCAGGTGACATGTTTGATAGCGAAATGTTTGAATGGACTCAGAGGCCTTGTTCTCCGGAGATTCTACCTAGTCCTGTGAAGGCCAAGGTCCTAGGTAGAGATGAGATTGATCTTACTCAAAAGAAGCTACCTAAAGTTAAAGTTGCATCATCCAAATGTAAAAACCGCAAAGCAGGAAGTGCAAGAAATACAGTTGCTAGACGAAGCATTGGGGTTTCACAAGAGGACAACATGGAATCATCTGCAGCAGCAACCATTAGTGAGCAACAAGATAGTCGTGGGACTTCTGGCACAATTATCAGGAATGATGTGAATACTGATGAAAATGTGAAAGCTAAAAGAGCTACAAGAAGCAAGGCTCAGAGTACACGAGTTCAGTCTGATCTAAATGTATCCAATGAAGCTGATGGGAAGCAGGGGACAAAGAGGAAAAGATCTAGCATTAAATCCTCTCCAGCTCACCCAATCGCAGGACCTAATGAGCTCTCACTTGGAACAGAAATTGTGGGAAAGGGGGATCAGGATCAAGCCCATGGTCCATCTGATACACATCCTGAAAAACGAAGTCCCACCGAGAAACCCTCTCTGAAGAAGAGGGGAAGAAAATCCAATGCAAGCTCCTCTTTAAAAGATCTATCTGGAAAAACACAAAAGAAGACTTCAGAGAAGAAATTGAAACTAGATTCCCATATGATCTCAAGCAAAGCTACACAACCGCATGGAAATGGTATTCTAACTGCTGGGTTGAATCAAGGGGGTGATAAACAAGATTCAAGAAACAATAGGAAATCCACTGTGGGTAAAGACGATCATACCATGCAAGTTATAGAGAAATGCTCAACGATAAACAAGTCTTCATCTGGAGGCAGTGCACATTTGCGACGATGTAATGGATCTTTAACGAAGAAATTCACATGTGCCTTTTGTCAGTGTTCAGAAGACACAGAGGCTTCAGGAGAAATGACTCACTACTACAGAGGTGAACCTGTCTCTGCGGATTTTAATGGTGGGTCTAAGGTCATACATGTTCACAAAAACTGTGCTGAATGGGCTCCAAATGTATACTTCAACGACCTTACCATAGTGAATCTTGATGTGGAGTTGACAAGAAGCCGGAGAATAAGTTGCAGCTGCTGTGGGCTTAAAGGCGCAGCACTTGGTTGTTACAATAAGAGTTGCAAGAATAGTTTTCATGTTACGTGTGCAAAACTCATACCAGAATGCAGATGGGACAATGTAAAATTTGTAATGCTATGCCCTTTGGATGCATCCATTAAGTTGCCCTGTGAAGAGGCTAATTCAAAAGACAGGAAATGCAAGCGTACTCCTAAAGAACCACTGCACTCTCAGCCTAAACAAGTATCTGGAAAAGCTAACATCCGTGAGCTCCATATCAAGCAGTTCCATGGATTTTCCAAGAAATTGGTCTTATCTTGCTCAGGGCTCACAGTTGAAGAGAAGACTGTTATTGCAGAATTTGCGGAACTGTCTGGAGTTACGATCTCAAAAAACTGGGATTCAACTGTTACACATGTTATTGCATCAATCAATGAAAACGGAGCCTGCAAAAGGACCCTCAAATTCATGATGGCAATCTTGGAGGGGAAATGGATACTAACCATTGATTGGATTAAGGCGTGTATGAAAAATACAAAATATGTAAGCGAGGAGCCATATGAGATCACTATGGATGTTCATGGAATACGAGAAGGACCTTATCTTGGAAGACAAAGAGCTTTGAAAAAGAAGCCAAAACTTTTTACTGGACTTAAGTTTTACATCATGGGAGATTTCGAGCTTGCTTACAAAGGATATCTTCAAGATCTGATTGTAGCAGCAGGAGGAACAATCTTGCGTAGGCGGCCTGTTTCTTCTGATGATAATGAAGCTTCAACAATCGTAGTATTTAGTGTTGAGCCTAGCAAGAAGAAAACTCTGACCCAAAGAAGATCTGATGCTGAAGCCTTGGCTAAATCTGCTAGAGCCAGAGCTGCAAGCAGTTCATGGGTTTTGGATTCTATTGCAGGTTGCCAAATTTTAGTCTTGATATAAAATAGTGAGACCATCTTTGTGTTTATTCTGTTGTTACTTGTTTGTAGGATTATGGAGAATTGTGTTAATACAAGGATTTTTCATTTTAATTATATTTATAAGGATTATTTATAGAATGCAATGG
CDS Sequence
Protein Sequence