Gene Details:

• Gene ID: AT4G19170
• Gene Symbol: CCD4, NCED4
• Gene Name: carotenoid cleavage dioxygenase 4, nine-cis-epoxycarotenoid dioxygenase 4
• Description: nine-cis-epoxycarotenoid dioxygenase 4;(source:Araport11)
• TAIR Accession: locus:2134796
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G19170.1

Gene Ontology:

• GO:0009507  — located in — chloroplast
• GO:0010436  — enables — carotenoid dioxygenase activity
• GO:1901811  — involved in — beta-carotene catabolic process
• GO:0010287  — located in — plastoglobule
• GO:0016121  — involved in — carotene catabolic process
• GO:0009570  — is active in — chloroplast stroma
• GO:0005515  — enables — protein binding
• GO:0005829  — located in — cytosol

Literature:

• Abscisic acid regulation of gene expression during water-deficit stress in the era of the Arabidopsis genome.   DOI:  10.1046/j.1365-3040.2002.00746.x ;  PMID:  11841660
• Transcriptome changes for Arabidopsis in response to salt, osmotic, and cold stress.   DOI:  10.1104/pp.008532 ;  PMID:  12481097
• Leaf vitamin C contents modulate plant defense transcripts and regulate genes that control development through hormone signaling.   DOI:  10.1105/tpc.010538 ;  PMID:  12671089
• Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.   DOI:  10.1023/a:1023005504702 ;  PMID:  12777052
• Expression profiling of cytokinin action in Arabidopsis.   DOI:  10.1104/pp.103.021436 ;  PMID:  12913156
• Microarray analysis of E2Fa-DPa-overexpressing plants uncovers a cross-talking genetic network between DNA replication and nitrogen assimilation.   DOI:  10.1242/jcs.00715 ;  PMID:  12953064
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis.   DOI:  10.1074/jbc.M313350200 ;  PMID:  14722088
• Comparative genomics in salt tolerance between Arabidopsis and aRabidopsis-related halophyte salt cress using Arabidopsis microarray.   DOI:  10.1104/pp.104.039909 ;  PMID:  15247402
• Reversible histone acetylation and deacetylation mediate genome-wide, promoter-dependent and locus-specific changes in gene expression during plant development.   DOI:  10.1534/genetics.104.033142 ;  PMID:  15371352
• Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development.   DOI:  10.1242/jcs.01360 ;  PMID:  15340011
• Microarray analysis of genes that respond to gamma-irradiation in Arabidopsis.   DOI:  10.1021/jf0486895 ;  PMID:  15713015
• Abscisic acid biosynthesis and catabolism.   DOI:  10.1146/annurev.arplant.56.032604.144046 ;  PMID:  15862093
• Systemic signalling of environmental cues in Arabidopsis leaves.   DOI:  10.1093/jxb/erj033 ;  PMID:  16330523
• Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.   DOI:  10.1074/jbc.M511939200 ;  PMID:  16414959
• Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.   DOI:  10.1104/pp.105.076083 ;  PMID:  16461379
• Genome-wide transcriptional analysis of the Arabidopsis thaliana interaction with the plant pathogen Pseudomonas syringae pv. tomato DC3000 and the human pathogen Escherichia coli O157:H7.   DOI:  10.1111/j.1365-313X.2006.02725.x ;  PMID:  16553894
• The early dark-response in Arabidopsis thaliana revealed by cDNA microarray analysis.   DOI:  10.1007/s11103-005-4211-x ;  PMID:  16514558
• Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family.   DOI:  10.1111/j.1365-313X.2006.02666.x ;  PMID:  16507088
• Gene expression profiles of Arabidopsis Cvi seeds during dormancy cycling indicate a common underlying dormancy control mechanism.   DOI:  10.1111/j.1365-313X.2006.02738.x ;  PMID:  16709196
• Abscisic acid antagonizes ethylene-induced hyponastic growth in Arabidopsis.   DOI:  10.1104/pp.106.092700 ;  PMID:  17158582
• Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings.   DOI:  10.1111/j.1365-313X.2006.02979.x ;  PMID:  17217462
• Genome-wide gene expression analysis reveals a critical role for CRYPTOCHROME1 in the response of Arabidopsis to high irradiance.   DOI:  10.1104/pp.107.098293 ;  PMID:  17478635
• Analysis of the Arabidopsis histidine kinase ATHK1 reveals a connection between vegetative osmotic stress sensing and seed maturation.   DOI:  10.1105/tpc.107.055871 ;  PMID:  18441212
• Tissue-Specific Apocarotenoid Glycosylation Contributes to Carotenoid Homeostasis in Arabidopsis Leaves.   DOI:  10.1104/pp.15.00243 ;  PMID:  26134165
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Phosphorylation of plastoglobular proteins in Arabidopsis thaliana.   DOI:  10.1093/jxb/erw091 ;  PMID:  26962209
• Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites.   DOI:  10.1093/jxb/erw356 ;  PMID:  27811075
• The Plastoglobule-Localized Metallopeptidase PGM48 Is a Positive Regulator of Senescence in Arabidopsis thaliana.   DOI:  10.1105/tpc.16.00745 ;  PMID:  27895226
• Molecular Modeling and Dynamic Simulation of Arabidopsis Thaliana Carotenoid Cleavage Dioxygenase Gene: A Comparison with Bixa orellana and Crocus Sativus.   DOI:  10.1002/jcb.25919 ;  PMID:  28145590
• The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis.   DOI:  10.1038/s41467-021-23112-0 ;  PMID:  33990595
• Fibrillin2 in chloroplast plastoglobules participates in photoprotection and jasmonate-induced senescence.   DOI:  10.1093/plphys/kiac166 ;  PMID:  35404409
• The 9-cis-epoxycarotenoid cleavage reaction is the key regulatory step of abscisic acid biosynthesis in water-stressed bean.   DOI:  10.1073/pnas.96.26.15354 ;  PMID:  10611388
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209
• Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles.   DOI:  10.1074/jbc.M511939200 ;  PMID:  16414959
• Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.   DOI:  10.1104/pp.105.076083 ;  PMID:  16461379
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequences: