Gene Details:

• Gene ID: AT4G18780
• Gene Symbol: ATCESA8, CESA8, IRX1, LEW2
• Gene Name: CELLULOSE SYNTHASE 8, CELLULOSE SYNTHASE 8, IRREGULAR XYLEM 1, LEAF WILTING 2
• Description: cellulose synthase family protein;(source:Araport11)
• TAIR Accession: locus:2124167
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G18780.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0010116  — acts upstream of or within — positive regulation of abscisic acid biosynthetic process
• GO:0030244  — involved in — cellulose biosynthetic process
• GO:0009833  — involved in — plant-type primary cell wall biogenesis
• GO:0016757  — enables — glycosyltransferase activity
• GO:0016759  — enables — cellulose synthase activity
• GO:0009505  — located in — plant-type cell wall
• GO:0050832  — acts upstream of or within — defense response to fungus
• GO:0042742  — acts upstream of or within — defense response to bacterium
• GO:0006970  — acts upstream of or within — response to osmotic stress
• GO:0016760  — enables — cellulose synthase (UDP-forming) activity
• GO:0005515  — enables — protein binding
• GO:0030244  — acts upstream of or within — cellulose biosynthetic process
• GO:0009834  — acts upstream of or within — plant-type secondary cell wall biogenesis
• GO:0009414  — acts upstream of or within — response to water deprivation
• GO:0005886  — located in — plasma membrane
• GO:0005886  — is active in — plasma membrane

Function-related keywords:

• root

Literature:

• Collapsed xylem phenotype of Arabidopsis identifies mutants deficient in cellulose deposition in the secondary cell wall.   DOI:  10.1105/tpc.9.5.689 ;  PMID:  9165747
• Disruption of the cellulose synthase gene, AtCesA8/IRX1, enhances drought and osmotic stress tolerance in Arabidopsis.   DOI:  10.1111/j.1365-313X.2005.02452.x ;  PMID:  15998313
• Interactions between MUR10/CesA7-dependent secondary cellulose biosynthesis and primary cell wall structure.   DOI:  10.1104/pp.106.087700 ;  PMID:  17041031
• The Arabidopsis irregular xylem8 mutant is deficient in glucuronoxylan and homogalacturonan, which are essential for secondary cell wall integrity.   DOI:  10.1105/tpc.106.047720 ;  PMID:  17237350
• Thaxtomin A affects CESA-complex density, expression of cell wall genes, cell wall composition, and causes ectopic lignification in Arabidopsis thaliana seedlings.   DOI:  10.1093/jxb/ern344 ;  PMID:  19269997
• Gibberellin acts through jasmonate to control the expression of MYB21, MYB24, and MYB57 to promote stamen filament growth in Arabidopsis.   DOI:  10.1371/journal.pgen.1000440 ;  PMID:  19325888
• Tryptophan-derived secondary metabolites in Arabidopsis thaliana confer non-host resistance to necrotrophic Plectosphaerella cucumerina fungi.   DOI:  10.1111/j.1365-313X.2010.04224.x ;  PMID:  20408997
• Phylogenetically distinct cellulose synthase genes support secondary wall thickening in arabidopsis shoot trichomes and cotton fiber.   DOI:  10.1111/j.1744-7909.2010.00934.x ;  PMID:  20377682
• SND2, a NAC transcription factor gene, regulates genes involved in secondary cell wall development in Arabidopsis fibres and increases fibre cell area in Eucalyptus.   DOI:  10.1186/1471-2229-11-173 ;  PMID:  22133261
• Functional analysis of complexes with mixed primary and secondary cellulose synthases.   DOI:  10.4161/psb.23179 ;  PMID:  23299322
• A R2R3-MYB transcription factor that is specifically expressed in cotton (Gossypium hirsutum) fibers affects secondary cell wall biosynthesis and deposition in transgenic Arabidopsis.   DOI:  10.1111/ppl.12317 ;  PMID:  25534543
• An Arabidopsis gene regulatory network for secondary cell wall synthesis.   DOI:  10.1038/nature14099 ;  PMID:  25533953
• Peroxidase 4 is involved in syringyl lignin formation in Arabidopsis thaliana.   DOI:  10.1016/j.jplph.2014.11.006 ;  PMID:  25506770
• Endo-β-1,4-glucanases impact plant cell wall development by influencing cellulose crystallization.   DOI:  10.1111/jipb.12353 ;  PMID:  25756224
• The Receptor-Like Kinase AtVRLK1 Regulates Secondary Cell Wall Thickening.   DOI:  10.1104/pp.17.01279 ;  PMID:  29678858
• Secondary Wall Regulating NACs Differentially Bind at the Promoter at a CELLULOSE SYNTHASE A4 Cis-eQTL.   DOI:  10.3389/fpls.2018.01895 ;  PMID:  30627134
• Collapsed xylem phenotype of Arabidopsis identifies mutants deficient in cellulose deposition in the secondary cell wall.   DOI:  10.1105/tpc.9.5.689 ;  PMID:  9165747
• Cell wall proteins in apoplastic fluids of Arabidopsis thaliana rosettes: identification by mass spectrometry and bioinformatics.   DOI:  10.1002/pmic.200400882 ;  PMID:  15593128
• Identification of novel genes in Arabidopsis involved in secondary cell wall formation using expression profiling and reverse genetics.   DOI:  10.1105/tpc.105.031542 ;  PMID:  15980264
• The Arabidopsis irregular xylem8 mutant is deficient in glucuronoxylan and homogalacturonan, which are essential for secondary cell wall integrity.   DOI:  10.1105/tpc.106.047720 ;  PMID:  17237350
• Impairment of cellulose synthases required for Arabidopsis secondary cell wall formation enhances disease resistance.   DOI:  10.1105/tpc.106.048058 ;  PMID:  17351116
• Arabidopsis MYB26/MALE STERILE35 regulates secondary thickening in the endothecium and is essential for anther dehiscence.   DOI:  10.1105/tpc.106.046391 ;  PMID:  17329564

Sequences: