Gene Details:
- Gene ID: AT4G17870
- Gene Symbol: PYR1, RCAR11
- Gene Name: PYRABACTIN RESISTANCE 1, regulatory component of ABA receptor 11
- Description: Polyketide cyclase/dehydrase and lipid transport superfamily protein;(source:Araport11)
- TAIR Accession: locus:2141040
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0025195 — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
Gene Ontology:
- GO:0009705 — located in — plant-type vacuole membrane
- GO:0005515 — enables — protein binding
- GO:0009738 — involved in — abscisic acid-activated signaling pathway
- GO:0042802 — enables — identical protein binding
- GO:1902584 — involved in — positive regulation of response to water deprivation
- GO:0010427 — enables — abscisic acid binding
- GO:0038023 — enables — signaling receptor activity
- GO:0009738 — acts upstream of or within — abscisic acid-activated signaling pathway
- GO:0005634 — located in — nucleus
- GO:0004864 — enables — protein phosphatase inhibitor activity
- GO:0005829 — located in — cytosol
- GO:0044389 — enables — ubiquitin-like protein ligase binding
- GO:0005634 — is active in — nucleus
- GO:0005737 — located in — cytoplasm
- GO:0005737 — is active in — cytoplasm
- GO:0042803 — enables — protein homodimerization activity
- GO:0019207 — enables — kinase regulator activity
- GO:0005886 — located in — plasma membrane
Function-related keywords:
Literature:
- Transcriptome changes for Arabidopsis in response to salt, osmotic, and cold stress. DOI: 10.1104/pp.008532 ; PMID: 12481097
- The FHY3 and FAR1 genes encode transposase-related proteins involved in regulation of gene expression by the phytochrome A-signaling pathway. DOI: 10.1046/j.1365-313x.2003.01741.x ; PMID: 12753585
- Genetic regulation of gene expression during shoot development in Arabidopsis. DOI: 10.1534/genetics.105.042275 ; PMID: 15956669
- Alternative and effective proteomic analysis in Arabidopsis. DOI: 10.1002/pmic.200700346 ; PMID: 17828791
- Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. DOI: 10.1104/pp.108.126375 ; PMID: 18775970
- Regulators of PP2C phosphatase activity function as abscisic acid sensors. DOI: 10.1126/science.1172408 ; PMID: 19407143
- PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis. DOI: 10.1111/j.1365-313X.2009.04054.x ; PMID: 19874541
- Crystallization of the plant hormone receptors PYL9/RCAR1, PYL5/RCAR8 and PYR1/RCAR11 in the presence of (+)-abscisic acid. DOI: 10.1107/S1744309110007037 ; PMID: 20383021
- In vitro reconstitution of an abscisic acid signalling pathway. DOI: 10.1038/nature08599 ; PMID: 19924127
- Identification and mechanism of ABA receptor antagonism. DOI: 10.1038/nsmb.1887 ; PMID: 20729862
- Action of natural abscisic acid precursors and catabolites on abscisic acid receptor complexes. DOI: 10.1104/pp.111.182584 ; PMID: 21976481
- Isolation and characterization of novel mutant loci suppressing the ABA hypersensitivity of the Arabidopsis coronatine insensitive 1-16 (coi1-16) mutant during germination and seedling growth. DOI: 10.1093/pcp/pcr174 ; PMID: 22156383
- Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation. DOI: 10.1073/pnas.1112838108 ; PMID: 22139369
- Over-expression of GsZFP1, an ABA-responsive C2H2-type zinc finger protein lacking a QALGGH motif, reduces ABA sensitivity and decreases stomata size. DOI: 10.1016/j.jplph.2012.03.019 ; PMID: 22705253
- Unique drought resistance functions of the highly ABA-induced clade A protein phosphatase 2Cs. DOI: 10.1104/pp.112.202408 ; PMID: 22829320
- HONSU, a protein phosphatase 2C, regulates seed dormancy by inhibiting ABA signaling in Arabidopsis. DOI: 10.1093/pcp/pct017 ; PMID: 23378449
- PYRABACTIN RESISTANCE1-LIKE8 plays an important role for the regulation of abscisic acid signaling in root. DOI: 10.1104/pp.112.208678 ; PMID: 23370718
- Temperature, light and nitrate sensing coordinate Arabidopsis seed dormancy cycling, resulting in winter and summer annual phenotypes. DOI: 10.1111/tpj.12186 ; PMID: 23590427
- Directly transforming PCR-amplified DNA fragments into plant cells is a versatile system that facilitates the transient expression assay. DOI: 10.1371/journal.pone.0057171 ; PMID: 23468926
- Arabidopsis nanodomain-delimited ABA signaling pathway regulates the anion channel SLAH3. DOI: 10.1073/pnas.1211667110 ; PMID: 23630285
- The PYL4 A194T mutant uncovers a key role of PYR1-LIKE4/PROTEIN PHOSPHATASE 2CA interaction for abscisic acid signaling and plant drought resistance. DOI: 10.1104/pp.113.224162 ; PMID: 23864556
- channels through reactive oxygen species-mediated activation of Ca2+ channels at the plasma membrane of intact Arabidopsis guard cells. DOI: 10.1104/pp.113.219758 ; PMID: 23899646
- Interactions between soybean ABA receptors and type 2C protein phosphatases. DOI: 10.1007/s11103-013-0114-4 ; PMID: 23934343
- Difference in abscisic acid perception mechanisms between closure induction and opening inhibition of stomata. DOI: 10.1104/pp.113.223826 ; PMID: 23946352
- Hydrogen sulfide generated by L-cysteine desulfhydrase acts upstream of nitric oxide to modulate abscisic acid-dependent stomatal closure. DOI: 10.1104/pp.114.245373 ; PMID: 25266633
- C2-domain abscisic acid-related proteins mediate the interaction of PYR/PYL/RCAR abscisic acid receptors with the plasma membrane and regulate abscisic acid sensitivity in Arabidopsis. DOI: 10.1105/tpc.114.129973 ; PMID: 25465408
- Lipoxygenase-derived 9-hydro(pero)xides of linoleoylethanolamide interact with ABA signaling to arrest root development during Arabidopsis seedling establishment. DOI: 10.1111/tpj.12821 ; PMID: 25752187
- A link between magnesium-chelatase H subunit and sucrose nonfermenting 1 (SNF1)-related protein kinase SnRK2.6/OST1 in Arabidopsis guard cell signalling in response to abscisic acid. DOI: 10.1093/jxb/erv341 ; PMID: 26175350
- The selectivity of 6-nor-ABA and 7'-nor-ABA for abscisic acid receptor subtypes. DOI: 10.1016/j.bmcl.2015.06.088 ; PMID: 26174552
- Involvement of OST1 Protein Kinase and PYR/PYL/RCAR Receptors in Methyl Jasmonate-Induced Stomatal Closure in Arabidopsis Guard Cells. DOI: 10.1093/pcp/pcw102 ; PMID: 27354421
- FYVE1/FREE1 Interacts with the PYL4 ABA Receptor and Mediates Its Delivery to the Vacuolar Degradation Pathway. DOI: 10.1105/tpc.16.00178 ; PMID: 27495812
- The single-subunit RING-type E3 ubiquitin ligase RSL1 targets PYL4 and PYR1 ABA receptors in plasma membrane to modulate abscisic acid signaling. DOI: 10.1111/tpj.12708 ; PMID: 25330042
- Arabidopsis Transcription Factors SPL1 and SPL12 Confer Plant Thermotolerance at Reproductive Stage. DOI: 10.1016/j.molp.2017.03.010 ; PMID: 28400323
- Reconstitution of Abscisic Acid Signaling from the Receptor to DNA via bHLH Transcription Factors. DOI: 10.1104/pp.16.01825 ; PMID: 28438792
- Abscisic acid signaling is involved in regulating the mitogen-activated protein kinase cascade module, AIK1-MKK5-MPK6. DOI: 10.1080/15592324.2017.1321188 ; PMID: 28494202
- Glucose triggers stomatal closure mediated by basal signaling through HXK1 and PYR/RCAR receptors in Arabidopsis. DOI: 10.1093/jxb/ery024 ; PMID: 29444316
- EL1-like Casein Kinases Suppress ABA Signaling and Responses by Phosphorylating and Destabilizing the ABA Receptors PYR/PYLs in Arabidopsis. DOI: 10.1016/j.molp.2018.02.012 ; PMID: 29505832
- Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity. DOI: 10.1016/j.celrep.2018.05.044 ; PMID: 29898403
- ABA Receptor Subfamily III Enhances Abscisic Acid Sensitivity and Improves the Drought Tolerance of Arabidopsis. DOI: 10.3390/ijms19071938 ; PMID: 30004422
- Young seedlings adapt to stress by retaining starch and retarding growth through ABA-Dependent and -independent pathways in Arabidopsis. DOI: 10.1016/j.bbrc.2019.06.023 ; PMID: 31186142
- RBR-Type E3 Ligases and the Ubiquitin-Conjugating Enzyme UBC26 Regulate Abscisic Acid Receptor Levels and Signaling. DOI: 10.1104/pp.19.00898 ; PMID: 31699847
- Dual-Reporting Transcriptionally Linked Genetically Encoded Fluorescent Indicators Resolve the Spatiotemporal Coordination of Cytosolic Abscisic Acid and Second Messenger Dynamics in Arabidopsis. DOI: 10.1105/tpc.19.00892 ; PMID: 32471862
- The effect of ABRE BINDING FACTOR 4-mediated FYVE1 on salt stress tolerance in Arabidopsis. DOI: 10.1016/j.plantsci.2020.110489 ; PMID: 32540007
- Counteraction of ABA-Mediated Inhibition of Seed Germination and Seedling Establishment by ABA Signaling Terminator in Arabidopsis. DOI: 10.1016/j.molp.2020.06.011 ; PMID: 32619606
- CEPR2 phosphorylates and accelerates the degradation of PYR/PYLs in Arabidopsis. DOI: 10.1093/jxb/erz302 ; PMID: 31232446
- Abscisic acid receptors maintain abscisic acid homeostasis by modulating UGT71C5 glycosylation activity. DOI: 10.1111/jipb.13030 ; PMID: 33205908
- ALKBH10B, an mRNA m(6)A Demethylase, Modulates ABA Response During Seed Germination in Arabidopsis. DOI: 10.3389/fpls.2021.712713 ; PMID: 34386031
- New Abscisic Acid Derivatives Revealed Adequate Regulation of Stomatal, Transcriptional, and Developmental Responses to Conquer Drought. DOI: 10.1021/acschembio.1c00451 ; PMID: 34379974
- GLABRA2-based selection efficiently enriches Cas9-generated nonchimeric mutants in the T1 generation. DOI: 10.1093/plphys/kiab356 ; PMID: 34608972
- The PYR-PP2C-CKL2 module regulates ABA-mediated actin reorganization during stomatal closure. DOI: 10.1111/nph.17933 ; PMID: 34932819
- BAK1 plays contrasting roles in regulating abscisic acid-induced stomatal closure and abscisic acid-inhibited primary root growth in Arabidopsis. DOI: 10.1111/jipb.13257 ; PMID: 35352463
- Monomerization of abscisic acid receptors through CARKs-mediated phosphorylation. DOI: 10.1111/nph.18149 ; PMID: 35388459
- MIW1 participates in ABA signaling through the regulation of MYB30 in Arabidopsis. DOI: 10.1016/j.plantsci.2023.111717 ; PMID: 37105379
- Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells. DOI: 10.1111/jipb.13536 ; PMID: 37226855
- Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling. DOI: 10.1016/j.jprot.2017.06.004 ; PMID: 28627464
Sequences:
cDNA Sequence
- >AT4G17870.1
TTTACCCTTACTATTTAATATAATTCCATGTTTACCCTTCATCTTCCCTCTAAAATCCAACACAGAGAGATTTCAACGCTAAATAAAGAGAGAGAGAGTCTAAAAGCTCGTCGTCGTCTTCAATGGTGAATCTCAAACCAATTGGATAAATAAAACAAAACAAAAAAAACTTCACAAAAAAAAAAAAAAGATCCAAATTACAACCATGCCTTCGGAGTTAACACCAGAAGAACGATCGGAACTAAAAAACTCAATCGCCGAGTTCCACACATACCAACTCGATCCAGGAAGCTGTTCATCACTCCACGCGCAACGAATCCACGCGCCTCCGGAACTCGTCTGGTCAATCGTACGACGATTCGACAAACCACAAACATACAAACACTTCATCAAATCCTGCTCCGTCGAACAAAACTTCGAGATGCGCGTCGGATGCACGCGCGACGTGATCGTCATCAGTGGATTACCGGCGAACACATCAACGGAAAGACTCGATATACTCGACGACGAACGGAGAGTTACCGGATTCAGTATCATCGGAGGCGAACATAGGCTGACGAATTACAAATCCGTTACGACGGTGCATCGGTTCGAGAAAGAGAATCGGATCTGGACGGTGGTTTTGGAATCTTACGTCGTTGATATGCCGGAAGGTAACTCGGAGGATGATACTCGTATGTTTGCTGATACGGTTGTGAAGCTTAATTTGCAGAAACTCGCGACGGTTGCTGAAGCTATGGCTCGTAACTCCGGTGACGGAAGTGGTTCTCAGGTGACGTGAAAATGAAGAAAAAAATATGATTTAATTTCTTTTATTAAAAACAAAATCCAGAAATGTTATTTATGTTGCTTCGTATAAGATTCTCTTCTTCTTTTGTCTGTTTTTGCTTTTTTAACCTCATATAGTCATATTTTTACCATTTTCTTATGATGAGAATGACGTGCAAGGTTATTTTGGGCATTTTATGTTTGTGGATAACTATGAATCTTTCCATTTTCGTTAGGTATATTCCGGCGAGTAAGTCAAAATTTTCGGCTATGCAACAAACTCTCATAAAAAGTTACAAAAAAACTTACTATAAAGTTACCAAAGGTTTATTTGACACAAAAAAAAAAAAAGTAAATAACCATTCGTGTAAGGTTTTACTTTTCTTTGAATGTAAAAAAAAAGAAAGGTTTTCCTTTTCTTTTCCTTTTGTTAAAAAAACATGGGGATAAGATTTTTTTCACGTGTTTTTTGCTGTTATTGCTTTAAGTATGGTAGATTTAGTGTGTGATTCGTATGAAAT
CDS Sequence
Protein Sequence