Gene Details:

• Gene ID: AT4G16890
• Gene Symbol: BAL, SNC1
• Gene Name: BALL, SUPPRESSOR OF NPR1-1, CONSTITUTIVE 1
• Description: TIR-NBS-LRR class disease resistance protein;(source:Araport11)
• TAIR Accession: locus:2129236
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G16890.1     AT4G16890.2     AT4G16890.3     AT4G16890.5     AT4G16890.4

Plant Ontology Annotations:

• PO:0000282  — trichome — tricoma (Spanish, exact), 毛茸、糸状体、毛 (Japanese, exact), seta (related), setae (related), capilli (narrow), capillus (narrow), cilia (narrow), cilium (narrow), glochid (narrow), glochidia (narrow), glochidium (narrow), hair (narrow), lepides (narrow), lepis (narrow), non-secretory trichome (narrow), scale (narrow), squama (narrow), squamae (narrow), squamella (narrow), squamellae (narrow), squamule (narrow), barb trichome (broad), bristle (broad)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0009733  — acts upstream of or within — response to auxin
• GO:0042742  — acts upstream of or within — defense response to bacterium
• GO:0009862  — acts upstream of or within — systemic acquired resistance, salicylic acid mediated signaling pathway
• GO:0005515  — enables — protein binding
• GO:0006952  — involved in — defense response
• GO:0007165  — involved in — signal transduction
• GO:0005737  — located in — cytoplasm
• GO:0002758  — located in — innate immune response-activating signaling pathway
• GO:0005634  — located in — nucleus
• GO:0000166  — enables — nucleotide binding
• GO:0043231  — located in — intracellular membrane-bounded organelle
• GO:0061809  — enables — NAD+ nucleotidase, cyclic ADP-ribose generating
• GO:0050135  — enables — NAD(P)+ nucleosidase activity
• GO:0043531  — enables — ADP binding
• GO:0005829  — located in — cytosol

Function-related keywords:

• trichome ,  root

Literature:

• Activation of an EDS1-mediated R-gene pathway in the snc1 mutant leads to constitutive, NPR1-independent pathogen resistance.   DOI:  10.1094/MPMI.2001.14.10.1131 ;  PMID:  11605952
• A gain-of-function mutation in a plant disease resistance gene leads to constitutive activation of downstream signal transduction pathways in suppressor of npr1-1, constitutive 1.   DOI:  10.1105/tpc.015842 ;  PMID:  14576290
• A putative nucleoporin 96 Is required for both basal defense and constitutive resistance responses mediated by suppressor of npr1-1,constitutive 1.   DOI:  10.1105/tpc.104.029926 ;  PMID:  15772285
• An importin alpha homolog, MOS6, plays an important role in plant innate immunity.   DOI:  10.1016/j.cub.2005.05.022 ;  PMID:  15964279
• The ubiquitin pathway is required for innate immunity in Arabidopsis.   DOI:  10.1111/j.1365-313X.2006.02978.x ;  PMID:  17217463
• Regulation of plant innate immunity by three proteins in a complex conserved across the plant and animal kingdoms.   DOI:  10.1101/gad.1559607 ;  PMID:  17575050
• The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death.   DOI:  10.1104/pp.107.100800 ;  PMID:  17631528
• Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway.   DOI:  10.1016/j.cub.2007.09.025 ;  PMID:  17919906
• The TIR-NB-LRR gene SNC1 is regulated at the transcript level by multiple factors.   DOI:  10.1094/MPMI-20-11-1449 ;  PMID:  17977156
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Two Prp19-like U-box proteins in the MOS4-associated complex play redundant roles in plant innate immunity.   DOI:  10.1371/journal.ppat.1000526 ;  PMID:  19629177
• MAP kinase phosphatase1 and protein tyrosine phosphatase1 are repressors of salicylic acid synthesis and SNC1-mediated responses in Arabidopsis.   DOI:  10.1105/tpc.109.067678 ;  PMID:  19789277
• The HEAT repeat protein ILITYHIA is required for plant immunity.   DOI:  10.1093/pcp/pcq038 ;  PMID:  20360018
• Activation of plant immune responses by a gain-of-function mutation in an atypical receptor-like kinase.   DOI:  10.1104/pp.110.158501 ;  PMID:  20508139
• Arabidopsis resistance protein SNC1 activates immune responses through association with a transcriptional corepressor.   DOI:  10.1073/pnas.1002828107 ;  PMID:  20647385
• Two putative RNA-binding proteins function with unequal genetic redundancy in the MOS4-associated complex.   DOI:  10.1104/pp.110.158931 ;  PMID:  20943852
• The Arabidopsis resistance-like gene SNC1 is activated by mutations in SRFR1 and contributes to resistance to the bacterial effector AvrRps4.   DOI:  10.1371/journal.ppat.1001172 ;  PMID:  21079790
• Nucleoporin MOS7/Nup88 contributes to plant immunity and nuclear accumulation of defense regulators.   DOI:  10.4161/nucl.1.4.12109 ;  PMID:  21327081
• Assessment of resistance pathways induced in Arabidopsis thaliana by hypovirulent Rhizoctonia spp. isolates.   DOI:  10.1094/PHYTO-09-10-0247 ;  PMID:  21385012
• Putative members of the Arabidopsis Nup107-160 nuclear pore sub-complex contribute to pathogen defense.   DOI:  10.1111/j.1365-313X.2012.04928.x ;  PMID:  22288649
• Abscisic acid deficiency antagonizes high-temperature inhibition of disease resistance through enhancing nuclear accumulation of resistance proteins SNC1 and RPS4 in Arabidopsis.   DOI:  10.1105/tpc.112.096198 ;  PMID:  22454454
• Nucleoporins Nup160 and Seh1 are required for disease resistance in Arabidopsis.   DOI:  10.4161/psb.21426 ;  PMID:  22902705
• Arabidopsis clade I TGA transcription factors regulate plant defenses in an NPR1-independent fashion.   DOI:  10.1094/MPMI-09-11-0256 ;  PMID:  22876961
• The ammonium/nitrate ratio is an input signal in the temperature-modulated, SNC1-mediated and EDS1-dependent autoimmunity of nudt6-2 nudt7.   DOI:  10.1111/tpj.12032 ;  PMID:  23004358
• A survey of dominant mutations in Arabidopsis thaliana.   DOI:  10.1016/j.tplants.2012.08.006 ;  PMID:  22995285
• Perturbation of cell cycle regulation triggers plant immune response via activation of disease resistance genes.   DOI:  10.1073/pnas.1217024110 ;  PMID:  23345424
• Disease resistance gene-induced growth inhibition is enhanced by rcd1 independent of defense activation in Arabidopsis.   DOI:  10.1104/pp.112.213363 ;  PMID:  23365132
• The cyclin L homolog MOS12 and the MOS4-associated complex are required for the proper splicing of plant resistance genes.   DOI:  10.1111/j.1365-313X.2012.04906.x ;  PMID:  22248079
• Regulation of transcription of nucleotide-binding leucine-rich repeat-encoding genes SNC1 and RPP4 via H3K4 trimethylation.   DOI:  10.1104/pp.113.214551 ;  PMID:  23690534
• MOS2 has redundant function with its homolog MOS2H and is required for proper splicing of SNC1.   DOI:  10.4161/psb.25372 ;  PMID:  23803746
• Crystallization and preliminary X-ray diffraction analyses of the TIR domains of three TIR-NB-LRR proteins that are involved in disease resistance in Arabidopsis thaliana.   DOI:  10.1107/S1744309113026614 ;  PMID:  24192368
• Monoubiquitination of histone 2B at the disease resistance gene locus regulates its expression and impacts immune responses in Arabidopsis.   DOI:  10.1104/pp.113.227801 ;  PMID:  24664204
• HSP90s are required for NLR immune receptor accumulation in Arabidopsis.   DOI:  10.1111/tpj.12573 ;  PMID:  24889324
• Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis.   DOI:  10.1105/tpc.15.00173 ;  PMID:  25966763
• Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis.   DOI:  10.1104/pp.15.00970 ;  PMID:  26408532
• IBR5 Modulates Temperature-Dependent, R Protein CHS3-Mediated Defense Responses in Arabidopsis.   DOI:  10.1371/journal.pgen.1005584 ;  PMID:  26451844
• Arabidopsis TAF15b Localizes to RNA Processing Bodies and Contributes to snc1-Mediated Autoimmunity.   DOI:  10.1094/MPMI-11-15-0246-R ;  PMID:  26713351
• Correction: IBR5 Modulates Temperature-Dependent, R Protein CHS3-Mediated Defense Responses in Arabidopsis.   DOI:  10.1371/journal.pgen.1005795 ;  PMID:  26735692
• AtCDC48A is involved in the turnover of an NLR immune receptor.   DOI:  10.1111/tpj.13251 ;  PMID:  27340941
• Global Regulation of Plant Immunity by Histone Lysine Methyl Transferases.   DOI:  10.1105/tpc.16.00012 ;  PMID:  27354553
• CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses.   DOI:  10.1111/tpj.13397 ;  PMID:  27747970
• NLR-associating transcription factor bHLH84 and its paralogs function redundantly in plant immunity.   DOI:  10.1371/journal.ppat.1004312 ;  PMID:  25144198
• Plant TRAF Proteins Regulate NLR Immune Receptor Turnover.   DOI:  10.1016/j.chom.2016.01.005 ;  PMID:  26867179
• A Role of Cytokinin Transporter in Arabidopsis Immunity.   DOI:  10.1094/MPMI-01-17-0011-R ;  PMID:  28398838
• The Arabidopsis Chromatin-Remodeling Factor CHR5 Regulates Plant Immune Responses and Nucleosome Occupancy.   DOI:  10.1093/pcp/pcx155 ;  PMID:  29048607
• MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.   DOI:  10.1111/tpj.13757 ;  PMID:  29086441
• The Arabidopsis SUMO E3 ligase SIZ1 mediates the temperature dependent trade-off between plant immunity and growth.   DOI:  10.1371/journal.pgen.1007157 ;  PMID:  29357355
• Individual components of paired typical NLR immune receptors are regulated by distinct E3 ligases.   DOI:  10.1038/s41477-018-0216-8 ;  PMID:  30082764
• SIZ1-Mediated SUMOylation of TPR1 Suppresses Plant Immunity in Arabidopsis.   DOI:  10.1016/j.molp.2018.12.002 ;  PMID:  30543996
• TCP transcription factors interact with ZED1-related kinases as components of the temperature-regulated immunity.   DOI:  10.1111/pce.13515 ;  PMID:  30652316
• Pathogen-Associated Molecular Pattern-Triggered Immunity Involves Proteolytic Degradation of Core Nonsense-Mediated mRNA Decay Factors During the Early Defense Response.   DOI:  10.1105/tpc.19.00631 ;  PMID:  32086363
• Plant E3 ligases SNIPER1 and SNIPER2 broadly regulate the homeostasis of sensor NLR immune receptors.   DOI:  10.15252/embj.2020104915 ;  PMID:  32557679
• RIN13-mediated disease resistance depends on the SNC1-EDS1/PAD4 signaling pathway in Arabidopsis.   DOI:  10.1093/jxb/eraa433 ;  PMID:  32937656
• Opposing functions of the plant TOPLESS gene family during SNC1-mediated autoimmunity.   DOI:  10.1371/journal.pgen.1009026 ;  PMID:  33621240
• Arabidopsis CBP60b is a central transcriptional activator of immunity.   DOI:  10.1093/plphys/kiab164 ;  PMID:  33848345
• Multiple chromatin-associated modules regulate expression of an intracellular immune receptor gene in Arabidopsis.   DOI:  10.1111/nph.18672 ;  PMID:  36509711
• Homeostasis of Arabidopsis R protein RPS2 is negatively regulated by the RING-type E3 ligase MUSE16.   DOI:  10.1093/jxb/erad026 ;  PMID:  36655859
• Puncta-localized TRAF domain protein TC1b contributes to the autoimmunity of snc1.   DOI:  10.1111/tpj.16155 ;  PMID:  36799433
• Cell-specific protein profiling in Arabidopsis thaliana trichomes: identification of trichome-located proteins involved in sulfur metabolism and detoxification.   DOI:  10.1016/j.phytochem.2004.03.026 ;  PMID:  15276459

Sequences: