Gene Details:

• Gene ID: AT4G16280
• Gene Symbol: FCA
• Gene Name: FLOWERING CONTROL LOCUS A
• Description: flowering time control protein FCA;(source:Araport11)
• TAIR Accession: locus:2130364
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G16280.1     AT4G16280.4     AT4G16280.3     AT4G16280.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)

Gene Ontology:

• GO:0000785  — located in — chromatin
• GO:0005515  — enables — protein binding
• GO:0003729  — enables — mRNA binding
• GO:0009909  — acts upstream of or within — regulation of flower development
• GO:0009793  — acts upstream of or within — embryo development ending in seed dormancy
• GO:1990904  — part of — ribonucleoprotein complex
• GO:0005737  — is active in — cytoplasm
• GO:0009553  — acts upstream of or within — embryo sac development
• GO:0005634  — is active in — nucleus
• GO:0031048  — acts upstream of or within — regulatory ncRNA-mediated heterochromatin formation
• GO:0005737  — located in — cytoplasm
• GO:0003723  — enables — RNA binding
• GO:0005634  — located in — nucleus
• GO:0016604  — located in — nuclear body

Function-related keywords:

• root ,  pollen tube cell

Literature:

• Mutations causing defects in the biosynthesis and response to gibberellins, abscisic acid and phytochrome B do not inhibit vernalization in Arabidopsis fca-1.   DOI:  10.1007/s004250050059 ;  PMID:  10787063
• The early-flowering mutant efs is involved in the autonomous promotion pathway of Arabidopsis thaliana.   DOI:  10.1242/dev.126.21.4763 ;  PMID:  10518493
• Late-flowering genes interact with early-flowering genes to regulate flowering time in Arabidopsis thaliana.   DOI:  10.1093/oxfordjournals.pcp.a029596 ;  PMID:  10501030
• Genetic interactions of the Arabidopsis flowering time gene FCA, with genes regulating floral initiation.   DOI:  10.1046/j.1365-313x.1999.00364.x ;  PMID:  10097382
• EMF genes interact with late-flowering genes to regulate Arabidopsis shoot development.   DOI:  10.1093/oxfordjournals.pcp.a029381 ;  PMID:  9615462
• Interaction of FLC and late-flowering mutations in Arabidopsis thaliana.   DOI:  10.1007/BF02174346 ;  PMID:  8628249
• Clonal analysis of the late flowering fca mutant of Arabidopsis thaliana: cell fate and cell autonomy.   DOI:  10.1242/dev.122.3.1041 ;  PMID:  8631249
• A genetic and physiological analysis of late flowering mutants in Arabidopsis thaliana.   DOI:  10.1007/BF00264213 ;  PMID:  1896021
• Effects of sugar on vegetative development and floral transition in Arabidopsis.   DOI:  10.1104/pp.127.1.252 ;  PMID:  11553753
• FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifs.   DOI:  10.1105/tpc.13.6.1427 ;  PMID:  11402170
• AtSWI3B, an Arabidopsis homolog of SWI3, a core subunit of yeast Swi/Snf chromatin remodeling complex, interacts with FCA, a regulator of flowering time.   DOI:  10.1093/nar/gkf458 ;  PMID:  12140326
• Phytochrome B and at Least One Other Phytochrome Mediate the Accelerated Flowering Response of Arabidopsis thaliana L. to Low Red/Far-Red Ratio.   DOI:  10.1104/pp.104.4.1311 ;  PMID:  12232170
• early in short days 4, a mutation in Arabidopsis that causes early flowering and reduces the mRNA abundance of the floral repressor FLC.   DOI:  10.1242/dev.00113 ;  PMID:  12403707
• EMF genes interact with late-flowering genes in regulating floral initiation genes during shoot development in Arabidopsis thaliana.   DOI:  10.1093/pcp/pce062 ;  PMID:  11382816
• Revisiting phase transition during flowering in Arabidopsis.   DOI:  10.1093/pcp/pcg109 ;  PMID:  12941876
• SWI3 subunits of putative SWI/SNF chromatin-remodeling complexes play distinct roles during Arabidopsis development.   DOI:  10.1105/tpc.105.031203 ;  PMID:  16055636
• Molecular characterization and phylogeny of U2AF35 homologs in plants.   DOI:  10.1104/pp.105.073858 ;  PMID:  16407443
• Overexpression of AGAMOUS-LIKE 28 (AGL28) promotes flowering by upregulating expression of floral promoters within the autonomous pathway.   DOI:  10.1016/j.bbrc.2006.07.121 ;  PMID:  16899218
• Role of SVP in the control of flowering time by ambient temperature in Arabidopsis.   DOI:  10.1101/gad.1518407 ;  PMID:  17322399
• Signalling mechanisms underlying the morphological responses of the root system to nitrogen in Arabidopsis thaliana.   DOI:  10.1093/jxb/erm114 ;  PMID:  17578866
• Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing.   DOI:  10.1126/science.1146565 ;  PMID:  17916737
• Functional redundancy and new roles for genes of the autonomous floral-promotion pathway.   DOI:  10.1104/pp.108.118927 ;  PMID:  18408043
• Patterns of polymorphism and demographic history in natural populations of Arabidopsis lyrata.   DOI:  10.1371/journal.pone.0002411 ;  PMID:  18545707
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Regulated RNA processing in the control of Arabidopsis flowering.   DOI:  10.1387/ijdb.051995vq ;  PMID:  16096981
• Conservation and divergence of FCA function between Arabidopsis and rice.   DOI:  10.1007/s11103-005-8105-8 ;  PMID:  16240176
• Heterologous expression of wheat VERNALIZATION 2 (TaVRN2) gene in Arabidopsis delays flowering and enhances freezing tolerance.   DOI:  10.1371/journal.pone.0008690 ;  PMID:  20084169
• The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.   DOI:  10.1016/j.devcel.2009.12.009 ;  PMID:  20079695
• RNA 3' processing functions of Arabidopsis FCA and FPA limit intergenic transcription.   DOI:  10.1073/pnas.1105334108 ;  PMID:  21536901
• The Arabidopsis mutant, fy-1, has an ABA-insensitive germination phenotype.   DOI:  10.1093/jxb/err452 ;  PMID:  22282534
• Transcription beyond borders has downstream consequences.   DOI:  10.4161/rna.18668 ;  PMID:  22258223
• Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome.   DOI:  10.1016/j.cell.2012.10.054 ;  PMID:  23313553
• The Arabidopsis thaliana RNA-binding protein FCA regulates thermotolerance by modulating the detoxification of reactive oxygen species.   DOI:  10.1111/nph.13079 ;  PMID:  25266977
• FCA mediates thermal adaptation of stem growth by attenuating auxin action in Arabidopsis.   DOI:  10.1038/ncomms6473 ;  PMID:  25400039
• A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis.   DOI:  10.1111/tpj.13607 ;  PMID:  28608936
• Research progress on the autonomous flowering time pathway in Arabidopsis.   DOI:  10.1007/s12298-017-0458-3 ;  PMID:  28878488
• Carbon nanoparticles influence photomorphogenesis and flowering time in Arabidopsis thaliana.   DOI:  10.1007/s00299-018-2277-6 ;  PMID:  29541883
• Arabidopsis FLL2 promotes liquid-liquid phase separation of polyadenylation complexes.   DOI:  10.1038/s41586-019-1165-8 ;  PMID:  31043738
• PRC2 recruitment and H3K27me3 deposition at FLC require FCA binding of COOLAIR.   DOI:  10.1126/sciadv.aau7246 ;  PMID:  31032401
• Density effects on late flowering mutants of Arabidopsis thaliana under continuous light.   DOI:  10.5511/plantbiotechnology.16.0622a ;  PMID:  31274994
• Regulation of Flowering Time by the RNA-Binding Proteins AtGRP7 and AtGRP8.   DOI:  10.1093/pcp/pcz124 ;  PMID:  31241165
• Molecular variation in a functionally divergent homolog of FCA regulates flowering time in Arabidopsis thaliana.   DOI:  10.1038/s41467-020-19666-0 ;  PMID:  33203912
• The U1 snRNP component RBP45d regulates temperature-responsive flowering in Arabidopsis.   DOI:  10.1093/plcell/koab273 ;  PMID:  34791475

Sequences: