Gene Details:

• Gene ID: AT3G51240
• Gene Symbol: F3H
• Gene Name:
• Description: flavanone 3-hydroxylase;(source:Araport11)
• TAIR Accession: locus:2081008
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G51240.1     AT3G51240.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0009813  — acts upstream of or within — flavonoid biosynthetic process
• GO:0009813  — involved in — flavonoid biosynthetic process
• GO:0005737  — located in — cytoplasm
• GO:0045486  — enables — naringenin 3-dioxygenase activity
• GO:0010224  — acts upstream of or within — response to UV-B

Germplasm Phenotype:

• CS2105575  — pale brown seeds due to reduced levels of brown pigment in seed coat (testa); reduced levels of anthocyanins in leaves, stems and other tissues
• CS2105576  — pale brown seeds due to reduced levels of brown pigment in seed coat (testa); reduced levels of anthocyanins in leaves, stems and other tissues
• CS8585  — double mutant; disruption of the synthesis of brown pigment in seed coat (testa); yellow seeds.
• CS8587  — double mutant; disruption of the synthesis of brown pigment in seed coat (testa); yellow seeds.
• CS8589  — double mutant; disruption of the synthesis of brown pigment in seed coat (testa); yellow seeds.
• CS8593  — double mutant; disruption of the synthesis of brown pigment in seed coat (testa); yellow seeds.
• CS8594  — double mutant; disruption of the synthesis of brown pigment in seed coat (testa); pale brown seeds.
• CS8600  — double mutant; altered phenylpropanoid metabolism; disruption of the synthesis of brown pigment in seed coat (testa), pale brown seeds.
• CS87  — pale brown seeds due to reduced levels of brown pigment in seed coat (testa); reduced levels of anthocyanins in leaves, stems and other tissues; probably deficient in flavonol synthase activity.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis.   DOI:  10.1046/j.1365-313x.1995.08050659.x ;  PMID:  8528278
• Regulation of anthocyanin biosynthesis in UV-A-irradiated cell cultures of carrot and in organs of intact carrot plants.   DOI:  10.1016/s0168-9452(01)00408-3 ;  PMID:  11448762
• Cloning and molecular analysis of structural genes involved in flavonoid and stilbene biosynthesis in grape (Vitis vinifera L.).   DOI:  10.1007/BF00029856 ;  PMID:  8193299
• Sucrose-specific induction of the anthocyanin biosynthetic pathway in Arabidopsis.   DOI:  10.1104/pp.105.072579 ;  PMID:  16384906
• MAX1, a regulator of the flavonoid pathway, controls vegetative axillary bud outgrowth in Arabidopsis.   DOI:  10.1073/pnas.0509463102 ;  PMID:  16387852
• Warm and cold parental reproductive environments affect seed properties, fitness, and cold responsiveness in Arabidopsis thaliana progenies.   DOI:  10.1111/j.1365-3040.2006.01615.x ;  PMID:  17238908
• Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development.   DOI:  10.1105/tpc.106.047688 ;  PMID:  17337630
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Architectural phenotypes in the transparent testa mutants of Arabidopsis thaliana.   DOI:  10.1093/jxb/ern323 ;  PMID:  19129166
• Auxin and ethylene induce flavonol accumulation through distinct transcriptional networks.   DOI:  10.1104/pp.111.172502 ;  PMID:  21427279
• Analysis of T-DNA alleles of flavonoid biosynthesis genes in Arabidopsis ecotype Columbia.   DOI:  10.1186/1756-0500-5-485 ;  PMID:  22947320
• De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae.   DOI:  10.1186/1475-2859-11-155 ;  PMID:  23216753
• Salicylic acid 3-hydroxylase regulates Arabidopsis leaf longevity by mediating salicylic acid catabolism.   DOI:  10.1073/pnas.1302702110 ;  PMID:  23959884
• The Arabidopsis thaliana mutant air1 implicates SOS3 in the regulation of anthocyanins under salt stress.   DOI:  10.1007/s11103-013-0099-z ;  PMID:  23925404
• A R2R3-MYB transcription factor, GmMYB12B2, affects the expression levels of flavonoid biosynthesis genes encoding key enzymes in transgenic Arabidopsis plants.   DOI:  10.1016/j.gene.2013.09.015 ;  PMID:  24060295
• AtROS1 overexpression provides evidence for epigenetic regulation of genes encoding enzymes of flavonoid biosynthesis and antioxidant pathways during salt stress in transgenic tobacco.   DOI:  10.1093/jxb/erv304 ;  PMID:  26116024
• Phytochrome-interacting factors PIF4 and PIF5 negatively regulate anthocyanin biosynthesis under red light in Arabidopsis seedlings.   DOI:  10.1016/j.plantsci.2015.06.001 ;  PMID:  26259175
• Update on transparent testa mutants from Arabidopsis thaliana: characterisation of new alleles from an isogenic collection.   DOI:  10.1007/s00425-014-2088-0 ;  PMID:  24903359
• GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation.   DOI:  10.1007/s00299-017-2102-7 ;  PMID:  28275852
• The COP1 Target SHI-RELATED SEQUENCE5 Directly Activates Photomorphogenesis-Promoting Genes.   DOI:  10.1105/tpc.18.00455 ;  PMID:  30150309
• The Peroxidative Cleavage of Kaempferol Contributes to the Biosynthesis of the Benzenoid Moiety of Ubiquinone in Plants.   DOI:  10.1105/tpc.18.00688 ;  PMID:  30429224
• Integrated bioinformatics analyses identified SCL3-induced regulatory network in Arabidopsis thaliana roots.   DOI:  10.1007/s10529-020-02850-z ;  PMID:  32125580
• Production of phenylpropanoids and flavonolignans from glycerol by metabolically engineered Escherichia coli.   DOI:  10.1002/bit.28008 ;  PMID:  34928495
• Proteomic characterization of isolated Arabidopsis clathrin-coated vesicles reveals evolutionarily conserved and plant-specific components.   DOI:  10.1093/plcell/koac071 ;  PMID:  35218346
• PHR1 positively regulates phosphate starvation-induced anthocyanin accumulation through direct upregulation of genes F3'H and LDOX in Arabidopsis.   DOI:  10.1007/s00425-022-03952-w ;  PMID:  35842503
• ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana.   DOI:  10.1007/s00425-022-03936-w ;  PMID:  35857143
• Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells.   DOI:  10.1111/jipb.13536 ;  PMID:  37226855
• Sucrose-specific induction of the anthocyanin biosynthetic pathway in Arabidopsis.   DOI:  10.1104/pp.105.072579 ;  PMID:  16384906

Sequences: