Gene Details:

• Gene ID: AT3G50950
• Gene Symbol: ZAR1
• Gene Name: HOPZ-ACTIVATED RESISTANCE 1
• Description: HOPZ-ACTIVATED RESISTANCE 1;(source:Araport11)
• TAIR Accession: locus:2078012
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G50950.1     AT3G50950.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0050829  — acts upstream of or within — defense response to Gram-negative bacterium
• GO:0042742  — involved in — defense response to bacterium
• GO:0050776  — involved in — regulation of immune response
• GO:0005515  — enables — protein binding
• GO:0098542  — involved in — defense response to other organism
• GO:0043621  — enables — protein self-association
• GO:0043531  — enables — ADP binding
• GO:0005634  — located in — nucleus

Germplasm Phenotype:

• CS65961  — No visible phenotype.
• CS65962  — No visible phenotype.
• CS65963  — No visible phenotype.
• CS65964  — No visible phenotype.
• SALK_013297  — Susceptible to P. syringae effectors HopBA1, F1, O1, X1, Z1.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• A large scale analysis of resistance gene homologues in Arachis.   DOI:  10.1007/s00438-003-0893-4 ;  PMID:  12928866
• Comprehensive comparison of auxin-regulated and brassinosteroid-regulated genes in Arabidopsis.   DOI:  10.1104/pp.103.034736 ;  PMID:  15047898
• The transcriptional innate immune response to flg22. Interplay and overlap with Avr gene-dependent defense responses and bacterial pathogenesis.   DOI:  10.1104/pp.103.036749 ;  PMID:  15181213
• Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures.   DOI:  10.1104/pp.104.039370 ;  PMID:  15235117
• A genome-wide survey of R gene polymorphisms in Arabidopsis.   DOI:  10.1105/tpc.106.042614 ;  PMID:  16798885
• Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis.   DOI:  10.1104/pp.106.082289 ;  PMID:  16920880
• Suppression by ABA of salicylic acid and lignin accumulation and the expression of multiple genes, in Arabidopsis infected with Pseudomonas syringae pv. tomato.   DOI:  10.1007/s10142-006-0041-4 ;  PMID:  17149585
• Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in Arabidopsis.   DOI:  10.1186/1471-2229-7-56 ;  PMID:  17956627
• Core genome responses involved in acclimation to high temperature.   DOI:  10.1104/pp.107.112060 ;  PMID:  18055584
• Comparative mapping of Brassica juncea and Arabidopsis thaliana using Intron Polymorphism (IP) markers: homoeologous relationships, diversification and evolution of the A, B and C Brassica genomes.   DOI:  10.1186/1471-2164-9-113 ;  PMID:  18315867
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Loss and retention of resistance genes in five species of the Brassicaceae family.   DOI:  10.1186/s12870-014-0298-z ;  PMID:  25365911
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• The Decoy Substrate of a Pathogen Effector and a Pseudokinase Specify Pathogen-Induced Modified-Self Recognition and Immunity in Plants.   DOI:  10.1016/j.chom.2015.08.004 ;  PMID:  26355215
• Comparative Genomics of Non-TNL Disease Resistance Genes from Six Plant Species.   DOI:  10.3390/genes8100249 ;  PMID:  28973974
• Reconstitution and structure of a plant NLR resistosome conferring immunity.   DOI:  10.1126/science.aav5870 ;  PMID:  30948527
• Ligand-triggered allosteric ADP release primes a plant NLR complex.   DOI:  10.1126/science.aav5868 ;  PMID:  30948526
• Two Arabidopsis Receptor-like Cytoplasmic Kinases SZE1 and SZE2 Associate with the ZAR1-ZED1 Complex and Are Required for Effector-Triggered Immunity.   DOI:  10.1016/j.molp.2019.03.012 ;  PMID:  30947022
• The pan-genome effector-triggered immunity landscape of a host-pathogen interaction.   DOI:  10.1126/science.aax4079 ;  PMID:  32054757
• Impact of DNA Demethylases on the DNA Methylation and Transcription of Arabidopsis NLR Genes.   DOI:  10.3389/fgene.2020.00460 ;  PMID:  32528522
• Identification of a Putative DNA-Binding Protein in Arabidopsis That Acts as a Susceptibility Hub and Interacts With Multiple Pseudomonas syringae Effectors.   DOI:  10.1094/MPMI-10-20-0291-R ;  PMID:  33373263
• Impact of DNA Demethylases on the DNA Methylation and Transcription of Arabidopsis NLR Genes.   DOI:  10.3389/fgene.2020.00460 ;  PMID:  32528522

Sequences: