Gene Details:

• Gene ID: AT3G50310
• Gene Symbol: AIK1, MAPKKK20, MKKK20
• Gene Name: ABA-INSENSITIVE PROTEIN KINASE 1, mitogen-activated protein kinase kinase kinase 20, MAPKK kinase 20
• Description: mitogen-activated protein kinase kinase kinase 20;(source:Araport11)
• TAIR Accession: locus:2074835
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G50310.1

Plant Ontology Annotations:

• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)

Gene Ontology:

• GO:0051301  — involved in — cell division
• GO:0048235  — acts upstream of or within — pollen sperm cell differentiation
• GO:0005515  — enables — protein binding
• GO:0090333  — acts upstream of or within — regulation of stomatal closure
• GO:0005737  — located in — cytoplasm
• GO:0009738  — involved in — abscisic acid-activated signaling pathway
• GO:0009737  — acts upstream of or within — response to abscisic acid
• GO:0004672  — enables — protein kinase activity
• GO:0009651  — acts upstream of or within — response to salt stress
• GO:0051510  — involved in — regulation of unidimensional cell growth
• GO:0019901  — enables — protein kinase binding
• GO:0006468  — involved in — protein phosphorylation
• GO:0005634  — located in — nucleus
• GO:0010082  — acts upstream of or within — regulation of root meristem growth
• GO:0000302  — acts upstream of or within — response to reactive oxygen species
• GO:0004708  — enables — MAP kinase kinase activity
• GO:0004709  — enables — MAP kinase kinase kinase activity
• GO:0007165  — involved in — signal transduction
• GO:0006468  — acts upstream of or within — protein phosphorylation
• GO:0009409  — acts upstream of or within — response to cold
• GO:0009414  — acts upstream of or within — response to water deprivation
• GO:0046777  — acts upstream of or within — protein autophosphorylation

Germplasm Phenotype:

• SALK_021755C  — Increased sensitivity to oryzalin, roots significantly shortened.
• SALK_049616C  — Decreased sensitivity to ABA during root growth, with longer and more pronounced root elongation zones (increased cell length and increased number of cells) compared to wild type. Stomatal closing less sensitive to ABA than wild type. Slightly greater stomatal density and reduced pavement cell density.

Function-related keywords:

• plant embryo ,  stamen ,  sepal ,  flower ,  collective leaf structure ,  pollen ,  pollen tube cell ,  pollen

Literature:

• The ENHANCER OF SHOOT REGENERATION 2 gene in Arabidopsis regulates CUP-SHAPED COTYLEDON 1 at the transcriptional level and controls cotyledon development.   DOI:  10.1093/pcp/pcl023 ;  PMID:  17056621
• Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays.   DOI:  10.1073/pnas.0611615104 ;  PMID:  17360592
• Elucidating the germination transcriptional program using small molecules.   DOI:  10.1104/pp.107.110841 ;  PMID:  18359847
• Comparative transcriptomics of Arabidopsis sperm cells.   DOI:  10.1104/pp.108.125229 ;  PMID:  18667720
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• The R2R3 MYB transcription factor DUO1 activates a male germline-specific regulon essential for sperm cell differentiation in Arabidopsis.   DOI:  10.1105/tpc.110.081059 ;  PMID:  21285328
• Arabidopsis MKKK20 is involved in osmotic stress response via regulation of MPK6 activity.   DOI:  10.1007/s00299-011-1157-0 ;  PMID:  21969089
• AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade.   DOI:  10.1104/pp.16.01386 ;  PMID:  27913741
• The Arabidopsis Mitogen-Activated Protein Kinase Kinase Kinase 20 (MKKK20) Acts Upstream of MKK3 and MPK18 in Two Separate Signaling Pathways Involved in Root Microtubule Functions.   DOI:  10.3389/fpls.2017.01352 ;  PMID:  28848569
• The Arabidopsis Mitogen-Activated Protein Kinase Kinase Kinase 20 (MKKK20) C-terminal domain interacts with MKK3 and harbors a typical DEF mammalian MAP kinase docking site.   DOI:  10.1080/15592324.2018.1503498 ;  PMID:  30081740
• Wounding and Insect Feeding Trigger Two Independent MAPK Pathways with Distinct Regulation and Kinetics.   DOI:  10.1105/tpc.19.00917 ;  PMID:  32265268
• MKKK20 works as an upstream triple-kinase of MKK3-MPK6-MYC2 module in Arabidopsis seedling development.   DOI:  10.1016/j.isci.2023.106049 ;  PMID:  36818282

Sequences: