Gene Details:
- Gene ID: AT3G50100
- Gene Symbol: SDN1
- Gene Name: small RNA degrading nuclease 1
- Description: small RNA degrading nuclease 1;(source:Araport11)
- TAIR Accession: locus:2083163
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Gene Ontology:
- GO:0035198 — enables — miRNA binding
- GO:0005737 — located in — cytoplasm
- GO:0005634 — is active in — nucleus
- GO:0004527 — enables — exonuclease activity
- GO:0003676 — enables — nucleic acid binding
- GO:0000175 — enables — 3-5-RNA exonuclease activity
- GO:0005515 — enables — protein binding
- GO:0010587 — acts upstream of or within — miRNA catabolic process
- GO:0044748 — enables — 3-5-exoribonuclease activity involved in mature miRNA 3-end processing GO:0044748 44317 F nuclease activity IDA in vitro binding assay NONE Publication:501781195|PMID:30181559 TAIR 2018-09-18 AT3G50100 locus:2083163 AT3G50100 acts upstream of or within miRNA catabolic process GO:0010587 29498 P other cellular processes IDA Enzyme assays NONE Publication:501728751|PMID:18787168 TAIR 2008-10-03 AT3G50100 locus:2083163 AT3G50100 acts upstream of or within miRNA catabolic process GO:0010587 29498 P other metabolic processes IDA Enzyme assays NONE Publication:501728751|PMID:18787168 TAIR 2008-10-03 AT3G50100 locus:2083163 AT3G50100 enables 3-5-exoribonuclease activity involved in mature miRNA 3-end processing
- GO:0008408 — enables — 3-5 exonuclease activity
Literature:
- AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling. DOI: 10.1104/pp.109.150185 ; PMID: 20032078
- ARGONAUTE10 promotes the degradation of miR165/6 through the SDN1 and SDN2 exonucleases in Arabidopsis. DOI: 10.1371/journal.pbio.2001272 ; PMID: 28231321
- Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. DOI: 10.1038/s41467-018-05942-7 ; PMID: 30181559
- Light Triggers the miRNA-Biogenetic Inconsistency for De-etiolated Seedling Survivability in Arabidopsis thaliana. DOI: 10.1016/j.molp.2019.10.011 ; PMID: 31678531
Sequences:
cDNA Sequence
- >AT3G50100.2
CAAAATTCCCACTTTTGTGGAGTCGAATTAGCTTCTCTGTAACTAACCATTCCGTTAAAATAGGTGCTTGACGAGTTGGTGAAGCTATTGCAGAGTCGAGATTTGCGTGGCGAAAATGGAAACTGGAAGGAATTTTTACATGTTTACGACAAAAATGCTGATTCACCAAGTGATCCTTCGAGGCGTTCTCATGAAGATTTGGTTCAGTTTCTGACAACTTTTAAGAAGAAAGAAGATTTGCAACTTCTGAAATGTCACGCCAATCATCTTCTGATTGAAAATTTGAAGCAAGAATCCCAAGATGAAGACACTCCTGAGCAGATGCTAGTTAGATTGACAGTTGAGCATCCGAGTTACTCGTTAGACTATTCTTTCAAGCCATACTCAGAGGACTGGTTTGTATCCGATGTTGGAATGAAGATGAAAAAGGTGATGGAATCAACTAACATGGTAGCTGTTGATTGTGAGATGGTTCTTTGTGAAGATGGGACTGAGGGTTTAGTTAGAGTTGGTGTTGTAGACCGTGATTTAAAGGTGATTCTTGACGAGTTTGTGAAACCGAACAAACCTGTTGTTGACTATAGGACAGACATTACAGGGATTACTGCTGAAGATATCGAAAATGCTAGTCTCTCTGTGGTAGATATACAGGAAACTTTGCAGCCCTTTCTTTCTACGGGTACGATTTTGGTTGGTCACAGTTTAAACAGAGATTTGGAAGTGTTAAAGATAGATCATCCTAAAGTAATCGATACCGCACTTGTATTCAAGTATCCGAATACACGAAAGCTCAGAAGACCTTCACTTAACAACCTTTGCAAGTCTATTTTGGGTTACGAAGTCCGAAAGACCGGTGTTCCTCATGATTGTGTACATGACGCATCAGCTGCGATGAAACTTGCACTTGCTGTTGTAGAGAAAAGAGTTGACACAACAATCAAACCATCTAAAGAGATGTTGGAGGTTGAGAAAGCAAAACTCTTTCTACATAAAATCCCTAACAATGTGCCATCTGAAGAGCTTGAGCAAGTTCTTTCTGGAAAGTTTACACTTGATGTGAAGCAAGCAAAAACACAGGGACGTTACTATTGTGCATTTGCTCTTTTCCATAGTTCAGAAGACGCAGATCAAGCATTTGAACACATTGATGGAATCGAAATGACGGATTCATTGGGTTTGCCACAAAAAGTGGTCATCATTAAGCTGAGTTCAGGATCAAGAGCTAGTATATATGTCCGTAAAATGGTTCAAGATGAATGATGCAACCTAGGATTAGATTAACTATTCAATGAATTGTTTTTTCAGATATTTGAAC - >AT3G50100.1
CAAAATTCCCACTTTTGTGGAGTCGAATTAGCTTCTCTGTAACTAACCATTCCGTTAAAATAGGTGCTTGACGAGTTGGTGAAGCTATTGCAGAGTCGAGATTTGCGTGGCGAAAATGGAAACTGGAAGGAATTTTTACATGTTTACGACAAAAATGCTGATTCACCAAGTGATCCTTCGAGGCGTTCTCATGAAGATTTGGTTCAGTTTCTGACAACTTTTAAGAAGAAAGAAGATTTGCAACTTCTGAAATGTCACGCCAATCATCTTCTGATTGAAAATTTGAAGCAAGAATCCCAAGATGAAGACACTCCTGAGCAGATGCTAGTTAGATTGACAGTTGAGCATCCGAGTTACTCGTTAGACTATTCTTTCAAGCCATACTCAGAGGACTGGTTTGTATCCGATGTTGGAATGAAGATGAAAAAGGTGATGGAATCAACTAACATGGTAGCTGTTGATTGTGAGATGGTTCTTTGTGAAGATGGGACTGAGGGTTTAGTTAGAGTTGGTGTTGTAGACCGTGATTTAAAGGTGATTCTTGACGAGTTTGTGAAACCGAACAAACCTGTTGTTGACTATAGGACAGACATTACAGGGATTACTGCTGAAGATATCGAAAATGCTAGTCTCTCTGTGGTAGATATACAGGAAACTTTGCAGCCCTTTCTTTCTACGGGTACGATTTTGGTTGGTCACAGTTTAAACAGAGATTTGGAAGTGTTAAAGATAGATCATCCTAAAGTAATCGATACCGCACTTGTATTCAAGTATCCGAATACACGAAAGCTCAGAAGACCTTCACTTAACAACCTTTGCAAGTCTATTTTGGGTTACGAAGTCCGAAAGACCGGTGTTCCTCATGATTGTGTACATGACGCATCAGCTGCGATGAAACTTGCACTTGCTGTTGTAGAGAAAAGAGTTGACACAACAATCAAACCATCTAAAGAGATGTTGGAGGTTGAGAAAGCAAAACTCTTTCTACATAAAATCCCTAACAATGTGCCATCTGAAGAGCTTGAGCAAGTTCTTTCTGGAAAGTTTACACTTGATGTGAAGCAAGCAAAAACACAGGGACGTTACTATTGTGCATTTGCTCTTTTCCATAGTTCAGAAGACGCAGATCAAGCATTTGAACACATTGATGGAATCGAAATGACGGATTCATTGGGTTTGCCACAAAAAGTGGTCATCATTAAGCTGAGTTCAGGATCAAGAGCTAGTATATATGTCCGTAAAATGGTTCAAGATGAATGATGCAACCTAGGATTAGATTAACTATTCAATGAATTGTTTTTTCAGATATTTGAAC
CDS Sequence
- >AT3G50100.2
ATGCTAGTTAGATTGACAGTTGAGCATCCGAGTTACTCGTTAGACTATTCTTTCAAGCCATACTCAGAGGACTGGTTTGTATCCGATGTTGGAATGAAGATGAAAAAGGTGATGGAATCAACTAACATGGTAGCTGTTGATTGTGAGATGGTTCTTTGTGAAGATGGGACTGAGGGTTTAGTTAGAGTTGGTGTTGTAGACCGTGATTTAAAGGTGATTCTTGACGAGTTTGTGAAACCGAACAAACCTGTTGTTGACTATAGGACAGACATTACAGGGATTACTGCTGAAGATATCGAAAATGCTAGTCTCTCTGTGGTAGATATACAGGAAACTTTGCAGCCCTTTCTTTCTACGGGTACGATTTTGGTTGGTCACAGTTTAAACAGAGATTTGGAAGTGTTAAAGATAGATCATCCTAAAGTAATCGATACCGCACTTGTATTCAAGTATCCGAATACACGAAAGCTCAGAAGACCTTCACTTAACAACCTTTGCAAGTCTATTTTGGGTTACGAAGTCCGAAAGACCGGTGTTCCTCATGATTGTGTACATGACGCATCAGCTGCGATGAAACTTGCACTTGCTGTTGTAGAGAAAAGAGTTGACACAACAATCAAACCATCTAAAGAGATGTTGGAGGTTGAGAAAGCAAAACTCTTTCTACATAAAATCCCTAACAATGTGCCATCTGAAGAGCTTGAGCAAGTTCTTTCTGGAAAGTTTACACTTGATGTGAAGCAAGCAAAAACACAGGGACGTTACTATTGTGCATTTGCTCTTTTCCATAGTTCAGAAGACGCAGATCAAGCATTTGAACACATTGATGGAATCGAAATGACGGATTCATTGGGTTTGCCACAAAAAGTGGTCATCATTAAGCTGAGTTCAGGATCAAGAGCTAGTATATATGTCCGTAAAATGGTTCAAGATGAATGA - >AT3G50100.1
ATGCTAGTTAGATTGACAGTTGAGCATCCGAGTTACTCGTTAGACTATTCTTTCAAGCCATACTCAGAGGACTGGTTTGTATCCGATGTTGGAATGAAGATGAAAAAGGTGATGGAATCAACTAACATGGTAGCTGTTGATTGTGAGATGGTTCTTTGTGAAGATGGGACTGAGGGTTTAGTTAGAGTTGGTGTTGTAGACCGTGATTTAAAGGTGATTCTTGACGAGTTTGTGAAACCGAACAAACCTGTTGTTGACTATAGGACAGACATTACAGGGATTACTGCTGAAGATATCGAAAATGCTAGTCTCTCTGTGGTAGATATACAGGAAACTTTGCAGCCCTTTCTTTCTACGGGTACGATTTTGGTTGGTCACAGTTTAAACAGAGATTTGGAAGTGTTAAAGATAGATCATCCTAAAGTAATCGATACCGCACTTGTATTCAAGTATCCGAATACACGAAAGCTCAGAAGACCTTCACTTAACAACCTTTGCAAGTCTATTTTGGGTTACGAAGTCCGAAAGACCGGTGTTCCTCATGATTGTGTACATGACGCATCAGCTGCGATGAAACTTGCACTTGCTGTTGTAGAGAAAAGAGTTGACACAACAATCAAACCATCTAAAGAGATGTTGGAGGTTGAGAAAGCAAAACTCTTTCTACATAAAATCCCTAACAATGTGCCATCTGAAGAGCTTGAGCAAGTTCTTTCTGGAAAGTTTACACTTGATGTGAAGCAAGCAAAAACACAGGGACGTTACTATTGTGCATTTGCTCTTTTCCATAGTTCAGAAGACGCAGATCAAGCATTTGAACACATTGATGGAATCGAAATGACGGATTCATTGGGTTTGCCACAAAAAGTGGTCATCATTAAGCTGAGTTCAGGATCAAGAGCTAGTATATATGTCCGTAAAATGGTTCAAGATGAATGA
Protein Sequence
- >AT3G50100.2
MLVRLTVEHPSYSLDYSFKPYSEDWFVSDVGMKMKKVMESTNMVAVDCEMVLCEDGTEGLVRVGVVDRDLKVILDEFVKPNKPVVDYRTDITGITAEDIENASLSVVDIQETLQPFLSTGTILVGHSLNRDLEVLKIDHPKVIDTALVFKYPNTRKLRRPSLNNLCKSILGYEVRKTGVPHDCVHDASAAMKLALAVVEKRVDTTIKPSKEMLEVEKAKLFLHKIPNNVPSEELEQVLSGKFTLDVKQAKTQGRYYCAFALFHSSEDADQAFEHIDGIEMTDSLGLPQKVVIIKLSSGSRASIYVRKMVQDE - >AT3G50100.1
MLVRLTVEHPSYSLDYSFKPYSEDWFVSDVGMKMKKVMESTNMVAVDCEMVLCEDGTEGLVRVGVVDRDLKVILDEFVKPNKPVVDYRTDITGITAEDIENASLSVVDIQETLQPFLSTGTILVGHSLNRDLEVLKIDHPKVIDTALVFKYPNTRKLRRPSLNNLCKSILGYEVRKTGVPHDCVHDASAAMKLALAVVEKRVDTTIKPSKEMLEVEKAKLFLHKIPNNVPSEELEQVLSGKFTLDVKQAKTQGRYYCAFALFHSSEDADQAFEHIDGIEMTDSLGLPQKVVIIKLSSGSRASIYVRKMVQDE