Gene Details:

• Gene ID: AT3G49850
• Gene Symbol: ATTRB3, TBP2, TRB3
• Gene Name: TELOMERE-BINDING PROTEIN 2, telomere repeat binding factor 3
• Description: telomere repeat binding factor 3;(source:Araport11)
• TAIR Accession: locus:2097325
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G49850.1     AT3G49850.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0006334  — involved in — nucleosome assembly
• GO:0000786  — part of — nucleosome
• GO:0000785  — part of — chromatin
• GO:0005730  — located in — nucleolus
• GO:0016070  — acts upstream of or within — RNA metabolic process
• GO:0003691  — enables — double-stranded telomeric DNA binding
• GO:0043047  — enables — single-stranded telomeric DNA binding
• GO:0043170  — acts upstream of or within — macromolecule metabolic process
• GO:0005634  — located in — nucleus
• GO:0042803  — enables — protein homodimerization activity

Germplasm Phenotype:

• CS73435  — homozygous triple mutant shows strong morphological defects: seedlings very small when grown on solid media, and when transplanted onto soil, often fail to survive and are completely infertile

Function-related keywords:

• root ,  vascular leaf ,  flower ,  stem ,  shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family and encodes a protein that binds telomere DNA repeats in vitro.   DOI:  10.1104/pp.103.026856 ;  PMID:  14576282
• Monitoring genome-wide changes in gene expression in response to endogenous cytokinin reveals targets in Arabidopsis thaliana.   DOI:  10.1016/s0014-5793(03)01194-3 ;  PMID:  14623097
• Interactions of putative telomere-binding proteins in Arabidopsis thaliana: identification of functional TRF2 homolog in plants.   DOI:  10.1016/j.febslet.2004.11.021 ;  PMID:  15589838
• The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.   DOI:  10.1007/s11103-005-2910-y ;  PMID:  16463103
• Single-Myb-histone proteins from Arabidopsis thaliana: a quantitative study of telomere-binding specificity and kinetics.   DOI:  10.1042/BJ20082195 ;  PMID:  19102728
• AtTRB1, a telomeric DNA-binding protein from Arabidopsis, is concentrated in the nucleolus and shows highly dynamic association with chromatin.   DOI:  10.1111/j.1365-313X.2009.04094.x ;  PMID:  19947985
• Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase.   DOI:  10.1111/tpj.12428 ;  PMID:  24397874
• Complementary Activities of TELOMERE REPEAT BINDING Proteins and Polycomb Group Complexes in Transcriptional Regulation of Target Genes.   DOI:  10.1105/tpc.15.00787 ;  PMID:  26721861
• WOX14 promotes bioactive gibberellin synthesis and vascular cell differentiation in Arabidopsis.   DOI:  10.1111/tpj.13513 ;  PMID:  28218997
• Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain.   DOI:  10.1104/pp.16.00214 ;  PMID:  28298478
• The plant Pontin and Reptin homologues, RuvBL1 and RuvBL2a, colocalize with TERT and TRB proteins in vivo, and participate in telomerase biogenesis.   DOI:  10.1111/tpj.14306 ;  PMID:  30834599
• Arabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14.   DOI:  10.1038/s41467-023-37263-9 ;  PMID:  36977663
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.   DOI:  10.1007/s11103-005-2910-y ;  PMID:  16463103
• Mapping of interaction domains of putative telomere-binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana.   DOI:  10.1016/j.febslet.2008.03.034 ;  PMID:  18387366

Sequences: