AT3G49670

Gene Details

Gene ID: AT3G49670
Gene Symbol: BAM2
Gene Name: BARELY ANY MERISTEM 2
Description: Leucine-rich receptor-like protein kinase family protein;(source:Araport11)
TAIR Accession: locus:2097310
Genome: Araport11_genome_release
Species: Arabidopsis thaliana

Functional Descriptions

PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
PO:0000013 — cauline leaf — hoja caulinar (Spanish, exact), 茎生葉、茎葉 (Japanese, exact)
PO:0009032 — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
PO:0009062 — gynoecium — ginoecio (Spanish, exact), gynaecium (exact), gynoecia (exact, plural), 雌蕊群 (Japanese, exact), Poaceae gynoecium (narrow), Zea gynoecium (narrow), apocarpous gynoecium (narrow), gynoecium of ear floret (narrow), gynoecium of lower floret of pedicellate spikelet of ear (narrow), gynoecium of lower floret of pedicellate spikelet of tassel (narrow), gynoecium of lower floret of sessile spikelet of ear (narrow), gynoecium of lower floret of sessile spikelet of tassel (narrow), gynoecium of tassel floret (narrow), gynoecium of upper floret of pedicellate spikelet of ear (narrow), gynoecium of upper floret of pedicellate spikelet of tassel (narrow), gynoecium of upper floret of sessile spikelet of ear (narrow), gynoecium of upper floret of sessile spikelet of tassel (narrow), syncarpous gynoecium (narrow), pistil (broad)
PO:0020148 — shoot apical meristem — SAM (exact), meristema apical del epiblasto (epiblastema) (Spanish, exact), 茎頂分裂組織 (Japanese, exact), primary shoot meristem (related), promeristem (broad)
PO:0000032 — tetrad of microspores — tétrada de las microsporas (Spanish, exact), 小胞子の四分子小胞子四分子 (Japanese, exact)
PO:0006010 — primary parietal cell — célula primaria parietal (Spanish, exact), 一次側膜細胞、壁細胞 (Japanese, exact)
PO:0006014 — male archesporial cell — célula masculina arquesporial (Spanish, exact), male archesporial initial (exact), 雄性胞原細胞 (Japanese, exact), anther archesporial cell (narrow)
PO:0006088 — primary sporogenous cell — célula esporógena primaria (Spanish, exact), 一次胞子形成細胞 (Japanese, exact)
PO:0009071 — anther wall tapetum — pollen sac tapetum (exact), portion of anther wall tapetal tissue (exact), tapete (Spanish, exact), 葯壁タペート組織 (Japanese, exact), Poaceae tapetum (narrow), Zea tapetum (narrow)
PO:0020047 — microsporocyte — microsporocito (Spanish, exact), 小胞子母細胞 (Japanese, exact), PMC (related), microspore mother cell (related), pollen mother cell (related), Poaceae microsporocyte (narrow), Zea microsporocyte (narrow)

GO:0005515 — enables — protein binding
GO:0048653 — acts upstream of or within — anther development
GO:0009755 — involved in — hormone-mediated signaling pathway
GO:0006468 — involved in — protein phosphorylation
GO:0048437 — acts upstream of or within — floral organ development
GO:0005886 — located in — plasma membrane
GO:0004674 — enables — protein serine/threonine kinase activity
GO:0048229 — acts upstream of or within — gametophyte development
GO:0010480 — acts upstream of or within — microsporocyte differentiation
GO:0038023 — enables — signaling receptor activity
GO:0010075 — acts upstream of or within — regulation of meristem growth
GO:0033612 — enables — receptor serine/threonine kinase binding
GO:0009934 — acts upstream of or within — regulation of meristem structural organization
GO:0005886 — is active in — plasma membrane

CS16305 — No visible phenotype.
CS16306 — No visible phenotype
CS31092 — No visible mutant phenotype.
bam1-1 bam2-1 — Anthers in double mutant plants appeared abnormal at a very early stage and lack the endothecium, middle, and tapetum layers. Further analyses revealed that cells interior to the epidermis (in anther tissue) acquire some characteristics of pollen mother cells (PMCs), suggesting defects in cell fate specification. The pollen mother-like cells degenerate before the completion of meiosis, suggesting that these cells are defective.
bam1-1 bam2-1 — Reduced shoot meristem size.
bam1-1 bam2-1 bam3-2 — Plants arrest early in development due to loss of shoot apical meristem but recover through adventitious shoot formation.
bam1-1 bam2-1 bam3-2 — Reduced numbers of stamens and carpels suggesting a reduction in floral meristem size.
bam1-1/bam2-1/clv1-11 — Triple mutant enhances the floral meristem defects of clv1-11 single mutant. Novel phenotypes include the existence of an enlarged indeterminate meristem in the center of each flower. Leaves are smaller and number of rosette leaves is increased.
bam1-1/bam2-1/clv2-1 — Number of carpels not statistically significant form that of clv2-1 alone.
bam1-1/bam2-1/clv3-2 — Triple mutant shows greater suppression of the clv3-2 with approximately 4.3 carpels per flower compared to clv3-2 single mutants which have approximately 6.7 carpels per flower.
bam1-3 bam2-3 — Altered leaf morphology: fewer veins than wild type and a distinct lack of higher-ordered veins.
bam1-3 bam2-3 — Anthers in double mutant plants appeared abnormal at a very early stage and lack the endothecium, middle, and tapetum layers. Further analyses revealed that cells interior to the epidermis (in anther tissue) acquire some characteristics of pollen mother cells (PMCs), suggesting defects in cell fate specification. The pollen mother-like cells degenerate before the completion of meiosis, suggesting that these cells are defective.
bam1-3 bam2-3 — Delayed in development: smaller in size and bolt and flower later than wild-type plants.
bam1-3 bam2-3 — Floral organ defects.
bam1-3 bam2-3 — Higher degree of branching in plants and have a longer lifespan. Almost completely sterile.
bam1-3 bam2-3 — Reduced shoot meristem size.
bam2-1 — No visible phenotype.
bam2-1/clv3-2 — Reduced number of carpels relative to clv3 single mutant.
bam2-3 — No visible phenotype.

Functional Keywords

Literature and News

Gene Resources

Sequences

cDNA Sequence

>AT3G49670.1
AAAAATCTCCCTCCAAGTAAATTCCAAAATAAAATAAAAATAATACTTTTACAATATACAAATAAAACTCATAAAAAACACACACACAATCTTCATCTTCCTCACTTACTCTCACCCTTTTTAAAACCAAACCCTAACTTACACAGAAAGAGAAGAAAAAAAACAAAAAAAAAATGAAGCTTCTTCTTCTCCTCCTCCTCCTCCTTCTCCTCCACATTTCTCATTCCTTCACCGTCGCTAAACCAATCACCGAGCTCCACGCTCTTCTCTCACTCAAATCCTCCTTCACCATCGACGAACACTCACCTCTCCTGACCTCATGGAACCTTTCAACAACTTTCTGTTCATGGACCGGTGTCACGTGCGACGTCTCTCTCCGTCACGTGACCTCTCTCGACCTCTCAGGTCTTAACCTCTCCGGAACTCTCTCCTCCGACGTAGCTCATTTACCTCTGCTACAGAATCTATCACTCGCTGCTAATCAGATCTCAGGTCCTATTCCGCCGCAAATCTCCAATCTCTATGAGCTTCGTCACCTCAATCTCTCCAATAATGTCTTCAACGGTTCATTTCCCGATGAACTCTCCTCTGGATTGGTGAATCTCCGTGTTCTTGACTTATACAACAACAATTTAACCGGAGATTTACCGGTTTCACTCACTAATCTCACTCAGCTCCGTCATCTTCACCTCGGTGGGAATTACTTCTCCGGCAAAATCCCGGCGACGTACGGAACCTGGCCTGTTCTCGAATACTTAGCGGTTTCCGGTAACGAGCTAACCGGTAAAATCCCTCCGGAGATCGGAAACCTAACGACTCTTCGTGAACTTTACATCGGATATTACAACGCTTTTGAAAATGGTCTTCCACCGGAGATTGGAAATTTATCAGAGCTTGTTCGGTTCGACGCTGCTAATTGTGGTTTAACCGGAGAGATTCCACCGGAGATTGGGAAGCTTCAGAAGCTAGATACGTTGTTTCTTCAAGTAAACGCATTTACAGGGACAATAACTCAAGAGCTGGGATTGATTTCAAGCTTGAAATCGATGGATCTGTCTAACAATATGTTTACCGGCGAGATTCCGACGAGTTTTTCACAGCTGAAGAACTTAACGCTTTTGAATCTCTTCAGGAATAAGCTCTACGGTGCTATACCTGAGTTCATCGGTGAAATGCCGGAGCTTGAAGTGTTGCAGCTTTGGGAGAACAATTTCACTGGTAGTATTCCTCAGAAATTGGGGGAAAATGGTAGATTAGTGATTCTTGATCTCTCTTCGAACAAACTCACCGGAACTCTGCCGCCGAATATGTGTTCTGGTAACCGGTTAATGACGTTAATCACTCTTGGCAACTTCTTGTTTGGTTCAATACCGGATTCGCTTGGTAAATGTGAGTCTCTGACCCGGATCCGGATGGGTGAGAATTTCCTTAACGGGTCGATTCCAAAGGAGCTCTTCGGGTTACCTAAATTATCTCAAGTGGAGCTCCAAGACAATTACCTTACCGGAGAGTTGCCAATAAGCGGAGGAGGAGTCTCTGGTGACCTTGGTCAGATTAGTCTTTCTAATAACCAGCTCTCTGGTTCATTACCTGCAGCTATTGGAAACTTGTCCGGTGTTCAAAAACTACTTCTTGATGGTAACAAGTTCTCTGGTTCGATTCCTCCCGAGATTGGGAGGCTTCAGCAGCTATCTAAGTTGGATTTTAGCCACAATCTGTTCTCCGGTCGGATCGCACCGGAGATCAGTCGTTGTAAGCTGCTAACGTTTGTTGATCTTAGCCGTAATGAGCTCTCAGGTGATATTCCTAATGAACTCACAGGTATGAAGATCTTGAATTACTTGAATCTTTCAAGAAACCATCTCGTTGGTTCCATACCTGTGACGATAGCATCAATGCAGAGTTTGACATCGGTTGATTTCTCTTACAACAATCTCTCCGGTTTAGTTCCCAGCACTGGACAGTTTAGTTACTTCAATTACACATCGTTTGTGGGTAACTCTCATCTTTGTGGTCCGTATTTGGGTCCTTGCGGCAAAGGAACTCACCAGTCTCATGTCAAACCTTTATCTGCTACTACGAAACTGTTACTCGTCCTTGGATTGCTCTTTTGTTCGATGGTGTTTGCTATAGTGGCCATAATCAAAGCTCGGTCCTTGCGAAATGCGAGTGAAGCCAAGGCATGGAGATTGACTGCTTTCCAGAGGCTAGACTTCACTTGTGACGATGTCTTGGACTCTCTCAAGGAAGACAACATCATCGGTAAAGGCGGTGCTGGGATTGTCTACAAAGGCACTATGCCTAAAGGCGACCTAGTCGCGGTCAAACGATTGGCTACAATGTCCCATGGATCTTCCCACGATCACGGGTTCAACGCCGAGATTCAGACGCTAGGTAGAATCAGACACAGACACATCGTGAGACTGCTCGGTTTTTGCTCCAACCACGAAACGAATCTCCTTGTGTACGAGTACATGCCTAATGGTAGCCTTGGAGAGGTTCTTCATGGAAAGAAAGGAGGTCATTTACATTGGAACACACGTTATAAGATAGCTCTTGAAGCAGCCAAGGGTCTTTGCTATCTCCACCATGATTGTTCCCCGTTGATCGTCCATAGAGATGTTAAATCCAACAACATCCTCCTCGATTCCAACTTCGAAGCTCATGTCGCCGACTTTGGTCTCGCCAAGTTCCTCCAAGATTCCGGTACTTCTGAATGTATGTCCGCAATTGCCGGCTCCTACGGCTACATAGCTCCAGAGTACGCGTATACATTGAAGGTAGATGAGAAGAGCGATGTGTATAGTTTCGGTGTTGTTCTTCTAGAACTCATCACCGGGAAAAAACCCGTCGGAGAATTTGGCGACGGCGTTGATATTGTTCAATGGGTGAGAAGCATGACGGATTCAAATAAAGATTGTGTGCTCAAAGTAATCGATCTTAGACTCTCTTCAGTTCCAGTTCACGAGGTAACACACGTCTTCTACGTTGCGTTGCTCTGCGTTGAAGAACAAGCGGTGGAGAGGCCGACGATGCGTGAAGTCGTTCAGATTCTCACTGAGATCCCAAAAATTCCTCTTTCGAAGCAGCAAGCGGCGGAATCAGACGTGACTGAGAAAGCTCCGGCGATTAATGAATCGTCGCCGGATTCAGGAAGTCCACCGGATCTTTTAAGTAATTAGACTTTCCGGCGATTGGGTTTGGTCATTGAGGGGCAAATTTGTCTTTCTAATTTTCTTGTCACCGACGTCTCGGTAGTGGAGTTAATTACTTAATTAGCCCGTTGTTGTCTGGTTCCGGTTAAGGCAACAATTAGTGGTTTAACTCTTAAGGTTGTTGCATTTCTTTTTTCACTGCTGCCACAATTATTCGTGTAGGAATTTTGAATATGTACATTGCGGTTGAATTTTGCATGATAAGTGGTTAATTTCAGGAAATCGAATTTCGAGAACATTATGGCTTATGCATATCAGCATATATATACATGCAGTTATGTATATGATCAATCTGCCCCCGGTTCAAGTATGTCAATTGTGTTAGACCAAAAAACACTTTTGCCCCTTATATTCTTAAGAACTTCATTTAGTTTCATACTCAAGCAAAAACTAA

CDS Sequence

>AT3G49670.1
ATGAAGCTTCTTCTTCTCCTCCTCCTCCTCCTTCTCCTCCACATTTCTCATTCCTTCACCGTCGCTAAACCAATCACCGAGCTCCACGCTCTTCTCTCACTCAAATCCTCCTTCACCATCGACGAACACTCACCTCTCCTGACCTCATGGAACCTTTCAACAACTTTCTGTTCATGGACCGGTGTCACGTGCGACGTCTCTCTCCGTCACGTGACCTCTCTCGACCTCTCAGGTCTTAACCTCTCCGGAACTCTCTCCTCCGACGTAGCTCATTTACCTCTGCTACAGAATCTATCACTCGCTGCTAATCAGATCTCAGGTCCTATTCCGCCGCAAATCTCCAATCTCTATGAGCTTCGTCACCTCAATCTCTCCAATAATGTCTTCAACGGTTCATTTCCCGATGAACTCTCCTCTGGATTGGTGAATCTCCGTGTTCTTGACTTATACAACAACAATTTAACCGGAGATTTACCGGTTTCACTCACTAATCTCACTCAGCTCCGTCATCTTCACCTCGGTGGGAATTACTTCTCCGGCAAAATCCCGGCGACGTACGGAACCTGGCCTGTTCTCGAATACTTAGCGGTTTCCGGTAACGAGCTAACCGGTAAAATCCCTCCGGAGATCGGAAACCTAACGACTCTTCGTGAACTTTACATCGGATATTACAACGCTTTTGAAAATGGTCTTCCACCGGAGATTGGAAATTTATCAGAGCTTGTTCGGTTCGACGCTGCTAATTGTGGTTTAACCGGAGAGATTCCACCGGAGATTGGGAAGCTTCAGAAGCTAGATACGTTGTTTCTTCAAGTAAACGCATTTACAGGGACAATAACTCAAGAGCTGGGATTGATTTCAAGCTTGAAATCGATGGATCTGTCTAACAATATGTTTACCGGCGAGATTCCGACGAGTTTTTCACAGCTGAAGAACTTAACGCTTTTGAATCTCTTCAGGAATAAGCTCTACGGTGCTATACCTGAGTTCATCGGTGAAATGCCGGAGCTTGAAGTGTTGCAGCTTTGGGAGAACAATTTCACTGGTAGTATTCCTCAGAAATTGGGGGAAAATGGTAGATTAGTGATTCTTGATCTCTCTTCGAACAAACTCACCGGAACTCTGCCGCCGAATATGTGTTCTGGTAACCGGTTAATGACGTTAATCACTCTTGGCAACTTCTTGTTTGGTTCAATACCGGATTCGCTTGGTAAATGTGAGTCTCTGACCCGGATCCGGATGGGTGAGAATTTCCTTAACGGGTCGATTCCAAAGGAGCTCTTCGGGTTACCTAAATTATCTCAAGTGGAGCTCCAAGACAATTACCTTACCGGAGAGTTGCCAATAAGCGGAGGAGGAGTCTCTGGTGACCTTGGTCAGATTAGTCTTTCTAATAACCAGCTCTCTGGTTCATTACCTGCAGCTATTGGAAACTTGTCCGGTGTTCAAAAACTACTTCTTGATGGTAACAAGTTCTCTGGTTCGATTCCTCCCGAGATTGGGAGGCTTCAGCAGCTATCTAAGTTGGATTTTAGCCACAATCTGTTCTCCGGTCGGATCGCACCGGAGATCAGTCGTTGTAAGCTGCTAACGTTTGTTGATCTTAGCCGTAATGAGCTCTCAGGTGATATTCCTAATGAACTCACAGGTATGAAGATCTTGAATTACTTGAATCTTTCAAGAAACCATCTCGTTGGTTCCATACCTGTGACGATAGCATCAATGCAGAGTTTGACATCGGTTGATTTCTCTTACAACAATCTCTCCGGTTTAGTTCCCAGCACTGGACAGTTTAGTTACTTCAATTACACATCGTTTGTGGGTAACTCTCATCTTTGTGGTCCGTATTTGGGTCCTTGCGGCAAAGGAACTCACCAGTCTCATGTCAAACCTTTATCTGCTACTACGAAACTGTTACTCGTCCTTGGATTGCTCTTTTGTTCGATGGTGTTTGCTATAGTGGCCATAATCAAAGCTCGGTCCTTGCGAAATGCGAGTGAAGCCAAGGCATGGAGATTGACTGCTTTCCAGAGGCTAGACTTCACTTGTGACGATGTCTTGGACTCTCTCAAGGAAGACAACATCATCGGTAAAGGCGGTGCTGGGATTGTCTACAAAGGCACTATGCCTAAAGGCGACCTAGTCGCGGTCAAACGATTGGCTACAATGTCCCATGGATCTTCCCACGATCACGGGTTCAACGCCGAGATTCAGACGCTAGGTAGAATCAGACACAGACACATCGTGAGACTGCTCGGTTTTTGCTCCAACCACGAAACGAATCTCCTTGTGTACGAGTACATGCCTAATGGTAGCCTTGGAGAGGTTCTTCATGGAAAGAAAGGAGGTCATTTACATTGGAACACACGTTATAAGATAGCTCTTGAAGCAGCCAAGGGTCTTTGCTATCTCCACCATGATTGTTCCCCGTTGATCGTCCATAGAGATGTTAAATCCAACAACATCCTCCTCGATTCCAACTTCGAAGCTCATGTCGCCGACTTTGGTCTCGCCAAGTTCCTCCAAGATTCCGGTACTTCTGAATGTATGTCCGCAATTGCCGGCTCCTACGGCTACATAGCTCCAGAGTACGCGTATACATTGAAGGTAGATGAGAAGAGCGATGTGTATAGTTTCGGTGTTGTTCTTCTAGAACTCATCACCGGGAAAAAACCCGTCGGAGAATTTGGCGACGGCGTTGATATTGTTCAATGGGTGAGAAGCATGACGGATTCAAATAAAGATTGTGTGCTCAAAGTAATCGATCTTAGACTCTCTTCAGTTCCAGTTCACGAGGTAACACACGTCTTCTACGTTGCGTTGCTCTGCGTTGAAGAACAAGCGGTGGAGAGGCCGACGATGCGTGAAGTCGTTCAGATTCTCACTGAGATCCCAAAAATTCCTCTTTCGAAGCAGCAAGCGGCGGAATCAGACGTGACTGAGAAAGCTCCGGCGATTAATGAATCGTCGCCGGATTCAGGAAGTCCACCGGATCTTTTAAGTAATTAG

Protein Sequence

>AT3G49670.1
MKLLLLLLLLLLLHISHSFTVAKPITELHALLSLKSSFTIDEHSPLLTSWNLSTTFCSWTGVTCDVSLRHVTSLDLSGLNLSGTLSSDVAHLPLLQNLSLAANQISGPIPPQISNLYELRHLNLSNNVFNGSFPDELSSGLVNLRVLDLYNNNLTGDLPVSLTNLTQLRHLHLGGNYFSGKIPATYGTWPVLEYLAVSGNELTGKIPPEIGNLTTLRELYIGYYNAFENGLPPEIGNLSELVRFDAANCGLTGEIPPEIGKLQKLDTLFLQVNAFTGTITQELGLISSLKSMDLSNNMFTGEIPTSFSQLKNLTLLNLFRNKLYGAIPEFIGEMPELEVLQLWENNFTGSIPQKLGENGRLVILDLSSNKLTGTLPPNMCSGNRLMTLITLGNFLFGSIPDSLGKCESLTRIRMGENFLNGSIPKELFGLPKLSQVELQDNYLTGELPISGGGVSGDLGQISLSNNQLSGSLPAAIGNLSGVQKLLLDGNKFSGSIPPEIGRLQQLSKLDFSHNLFSGRIAPEISRCKLLTFVDLSRNELSGDIPNELTGMKILNYLNLSRNHLVGSIPVTIASMQSLTSVDFSYNNLSGLVPSTGQFSYFNYTSFVGNSHLCGPYLGPCGKGTHQSHVKPLSATTKLLLVLGLLFCSMVFAIVAIIKARSLRNASEAKAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGTMPKGDLVAVKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWNTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELITGKKPVGEFGDGVDIVQWVRSMTDSNKDCVLKVIDLRLSSVPVHEVTHVFYVALLCVEEQAVERPTMREVVQILTEIPKIPLSKQQAAESDVTEKAPAINESSPDSGSPPDLLSN