Gene Details:

• Gene ID: AT3G49250
• Gene Symbol: DMS3, IDN1
• Gene Name: DEFECTIVE IN MERISTEM SILENCING 3, INVOLVED IN DE NOVO 1
• Description: defective in meristem silencing 3;(source:Araport11)
• TAIR Accession: locus:2082876
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G49250.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Gene Ontology:

• GO:0006306  — acts upstream of or within — DNA methylation
• GO:0005515  — enables — protein binding
• GO:0031047  — acts upstream of or within — regulatory ncRNA-mediated gene silencing
• GO:0042803  — enables — protein homodimerization activity
• GO:0000419  — part of — RNA polymerase V complex

Germplasm Phenotype:

• CS69174  — No visible phenotype.
• dms3-1  — WT morphological phenotype. Decreased DNA methylation of target genes.
• nuwa-1  — All pollen grains of heterozygote plant are viable. Mutation does not affect male gametophyte viability.
• nuwa-1  — embryo lethal.
• nuwa-2  — All pollen grains of heterozygote plant are viable. Mutation does not affect male gametophyte viability.
• nuwa-2  — embryo lethal.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  collective leaf structure

Literature:

• Novel and stress-regulated microRNAs and other small RNAs from Arabidopsis.   DOI:  10.1105/tpc.104.022830 ;  PMID:  15258262
• The Arabidopsis thaliana transcriptome in response to Agrobacterium tumefaciens.   DOI:  10.1094/MPMI-19-0665 ;  PMID:  16776300
• A structural-maintenance-of-chromosomes hinge domain-containing protein is required for RNA-directed DNA methylation.   DOI:  10.1038/ng.119 ;  PMID:  18425128
• The C-terminal region (640-967) of Arabidopsis CPL1 interacts with the abiotic and ABA-responsive transcription factors.   DOI:  10.1016/j.bbrc.2008.05.161 ;  PMID:  18541146
• RNA polymerase V transcription guides ARGONAUTE4 to chromatin.   DOI:  10.1038/ng.365 ;  PMID:  19377477
• directed DNA methylation in Arabidopsis.   DOI:  10.1016/j.cub.2010.03.062 ;  PMID:  20409711
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• Involvement of a GHKL ATPase in RNA-directed DNA methylation in Arabidopsis thaliana.   DOI:  10.1016/j.cub.2012.03.061 ;  PMID:  22560611
• RNA polymerase V-dependent small RNAs in Arabidopsis originate from small, intergenic loci including most SINE repeats.   DOI:  10.4161/epi.20290 ;  PMID:  22647529
• Antisilencing role of the RNA-directed DNA methylation pathway and a histone acetyltransferase in Arabidopsis.   DOI:  10.1073/pnas.1208557109 ;  PMID:  22733760
• Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome.   DOI:  10.1016/j.cell.2012.10.054 ;  PMID:  23313553
• The SET domain proteins SUVH2 and SUVH9 are required for Pol V occupancy at RNA-directed DNA methylation loci.   DOI:  10.1371/journal.pgen.1003948 ;  PMID:  24465213
• Angiosperms Are Unique among Land Plant Lineages in the Occurrence of Key Genes in the RNA-Directed DNA Methylation (RdDM) Pathway.   DOI:  10.1093/gbe/evv171 ;  PMID:  26338185
• Anaphase-promoting complex/cyclosome regulates RdDM activity by degrading DMS3 in Arabidopsis.   DOI:  10.1073/pnas.1816652116 ;  PMID:  30760603
• CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation.   DOI:  10.1038/s41467-019-11759-9 ;  PMID:  31477705
• Roles of IDM3 and SDJ1/2/3 in Establishment and/or Maintenance of DNA Methylation in Arabidopsis.   DOI:  10.1093/pcp/pcab091 ;  PMID:  34185870
• BPM1 regulates RdDM-mediated DNA methylation via a cullin 3 independent mechanism.   DOI:  10.1007/s00299-022-02911-9 ;  PMID:  36066603
• Regulatory mechanism of a heat-activated retrotransposon by DDR complex in Arabidopsis thaliana.   DOI:  10.3389/fpls.2022.1048957 ;  PMID:  36618621
• RETINOBLASTOMA-RELATED interactions with key factors of the RNA-directed DNA methylation (RdDM) pathway and its influence on root development.   DOI:  10.1007/s00425-023-04135-x ;  PMID:  37120771

Sequences: