Gene Details:

• Gene ID: AT3G49240
• Gene Symbol: emb1796, NUWA
• Gene Name: embryo defective 1796, NUWA
• Description: Pentatricopeptide repeat (PPR) superfamily protein;(source:Araport11)
• TAIR Accession: locus:2082871
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G49240.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Gene Ontology:

• GO:0009793  — acts upstream of or within — embryo development ending in seed dormancy
• GO:0009960  — acts upstream of or within — endosperm development
• GO:0005515  — enables — protein binding
• GO:0006349  — acts upstream of or within — regulation of gene expression by genomic imprinting
• GO:0005739  — located in — mitochondrion
• GO:0005524  — enables — ATP binding
• GO:0005739  — is active in — mitochondrion
• GO:0009507  — located in — chloroplast
• GO:0003729  — enables — mRNA binding

Germplasm Phenotype:

• CS16034  — Embryo fails to develop beyond the globular stage. Consisten and severe developmental arrest at the mid-globular stage, resulting in a slightly irregular embryo proper consisting of 32-64 cells. Arrested embryos persist in this early arrested stage into late-stage seeds, without any apparent further growth.
• CS16034  — embryo defective; developmental arrest of mutant embryos
• nuwa-1  — All pollen grains of heterozygote plant are viable. Mutation does not affect male gametophyte viability.
• nuwa-1  — embryo lethal.
• nuwa-2  — All pollen grains of heterozygote plant are viable. Mutation does not affect male gametophyte viability.
• nuwa-2  — embryo lethal.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure

Literature:

• Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins reveals their essential role in organelle biogenesis.   DOI:  10.1105/tpc.104.022236 ;  PMID:  15269332
• Identification of genes required for embryo development in Arabidopsis.   DOI:  10.1104/pp.104.045179 ;  PMID:  15266054
• Arabidopsis response regulator, ARR22, ectopic expression of which results in phenotypes similar to the wol cytokinin-receptor mutant.   DOI:  10.1093/pcp/pch128 ;  PMID:  15356332
• Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.   DOI:  10.1007/s00425-004-1452-x ;  PMID:  15647901
• Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry.   DOI:  10.1093/pcp/pci033 ;  PMID:  15695462
• Arabidopsis GLUTAMINE-RICH PROTEIN23 is essential for early embryogenesis and encodes a novel nuclear PPR motif protein that interacts with RNA polymerase II subunit III.   DOI:  10.1105/tpc.105.039495 ;  PMID:  16489121
• Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis.   DOI:  10.1104/pp.110.168120 ;  PMID:  21139083
• Multiple PPR protein interactions are involved in the RNA editing system in Arabidopsis mitochondria and plastids.   DOI:  10.1073/pnas.1705815114 ;  PMID:  28761003
• Two interacting PPR proteins are major Arabidopsis editing factors in plastid and mitochondria.   DOI:  10.1073/pnas.1705780114 ;  PMID:  28760958
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• GRP23 plays a core role in E-type editosomes via interacting with MORFs and atypical PPR-DYWs in Arabidopsis mitochondria.   DOI:  10.1073/pnas.2210978119 ;  PMID:  36122211
• Arabidopsis emb175 and other ppr knockout mutants reveal essential roles for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.   DOI:  10.1007/s00425-004-1452-x ;  PMID:  15647901
• Analysis of the soluble ATP-binding proteome of plant mitochondria identifies new proteins and nucleotide triphosphate interactions within the matrix.   DOI:  10.1021/pr060403j ;  PMID:  17137349
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequences: