Gene Details:

• Gene ID: AT3G48900
• Gene Symbol: AtSEND1, SEND1
• Gene Name:
• Description: single-stranded DNA endonuclease family protein;(source:Araport11)
• TAIR Accession: locus:2099463
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G48900.1     AT3G48900.2     AT3G48900.3

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)

Gene Ontology:

• GO:0009650  — involved in — UV protection
• GO:0006259  — acts upstream of or within — DNA metabolic process
• GO:0017108  — enables — 5-flap endonuclease activity GO:0017108 8073 F nuclease activity IBA none PANTHER:PTN000118612|PomBase:SPAC3G6.06c|TAIR:locus:2099463|FB:FBgn0263831|UniProtKB:P39748|SGD:S000005559|SGD:S000001596|TAIR:locus:2025447|UniProtKB:Q17RS7 Communication:501741973 2023-06-07 AT3G48900 locus:2099463 AT3G48900 enables crossover junction DNA endonuclease activity GO:0008821 2009 F catalytic activity IDA Enzyme assays Publication:501760496|PMID:25037209 dko 2014-07-30 AT3G48900 locus:2099463 AT3G48900 involved in DNA repair GO:0006281 4741 P other cellular processes IMP none Publication:501767564|PMID:26704385 2021-03-31 AT3G48900 gene:4515101624 AT3G48900.2 located in nucleus GO:0005634 537 C nucleus ISM predicted protein features AnalysisReference:501780126 rkaundal 2018-08-31 AT3G48900 locus:2099463 AT3G48900 enables 5-flap endonuclease activity
• GO:0000723  — involved in — telomere maintenance
• GO:0008821  — enables — crossover junction DNA endonuclease activity
• NONE  — enables — 5-flap endonuclease activity GO:0017108 8073 F catalytic activity IBA none PANTHER:PTN000118612|PomBase:SPAC3G6.06c|TAIR:locus:2099463|FB:FBgn0263831|UniProtKB:P39748|SGD:S000005559|SGD:S000001596|TAIR:locus:2025447|UniProtKB:Q17RS7 Communication:501741973 2023-06-07 AT3G48900 gene:2099462 AT3G48900.1 located in nucleus GO:0005634 537 C nucleus ISM predicted protein features AnalysisReference:501780126 rkaundal 2018-08-31 AT3G48900 gene:6532550621 AT3G48900.3 located in nucleus GO:0005634 537 C nucleus ISM predicted protein features AnalysisReference:501780126 rkaundal 2018-08-31 AT3G48900 locus:2099463 AT3G48900 involved in DNA repair GO:0006281 4741 P DNA metabolic process IMP none Publication:501767564|PMID:26704385 2021-03-31 AT3G48920 locus:2101273 AT3G48920 involved in regulation of DNA-templated transcription GO:0006355 7461 P other metabolic processes IBA none PANTHER:PTN008726895|TAIR:locus:2103459|TAIR:locus:2182275|TAIR:locus:2131844|TAIR:locus:2195528 Communication:501741973 2023-06-07 AT3G48920 locus:2101273 AT3G48920 enables transcription cis-regulatory region binding GO:0000976 35767 F nucleic acid binding IBA none PANTHER:PTN008726895|TAIR:locus:2195528|TAIR:locus:2146804|TAIR:locus:2182275|TAIR:locus:2145121|TAIR:locus:2133382|TAIR:locus:2103459|TAIR:locus:2012375|TAIR:locus:2027508 Communication:501741973 2023-06-07 AT3G48920 locus:2101273 AT3G48920 enables transcription cis-regulatory region binding GO:0000976 35767 F DNA binding IBA none PANTHER:PTN008726895|TAIR:locus:2195528|TAIR:locus:2146804|TAIR:locus:2182275|TAIR:locus:2145121|TAIR:locus:2133382|TAIR:locus:2103459|TAIR:locus:2012375|TAIR:locus:2027508 Communication:501741973 2023-06-07 AT3G48920 locus:2101273 AT3G48920 involved in regulation of DNA-templated transcription GO:0006355 7461 P nucleobase-containing compound metabolic process IBA none PANTHER:PTN008726895|TAIR:locus:2103459|TAIR:locus:2182275|TAIR:locus:2131844|TAIR:locus:2195528 Communication:501741973 2023-06-07 AT3G48920 gene:2101272 AT3G48920.1 located in nucleus GO:0005634 537 C nucleus ISM predicted protein features AnalysisReference:501780126 rkaundal 2018-08-31 AT3G48920 locus:2101273 AT3G48920 involved in regulation of DNA-templated transcription GO:0006355 7461 P biosynthetic process IBA none PANTHER:PTN008726895|TAIR:locus:2103459|TAIR:locus:2182275|TAIR:locus:2131844|TAIR:locus:2195528 Communication:501741973 2023-06-07 AT3G48920 locus:2101273 AT3G48920 is active in nucleus GO:0005634 537 C nucleus IBA none PANTHER:PTN008726895|TAIR:locus:2088187|TAIR:locus:2195528|TAIR:locus:2131844|TAIR:locus:2182275 Communication:501741973 2023-06-07 AT3G48920 locus:2101273 AT3G48920 enables DNA-binding transcription factor activity GO:0003700 4449 F DNA-binding transcription factor activity ISS Recognized domains Publication:1345963|PMID:11118137 TAIR 2003-06-06 AT3G48920 locus:2101273 AT3G48920 involved in regulation of DNA-templated transcription GO:0006355 7461 P other cellular processes IBA none PANTHER:PTN008726895|TAIR:locus:2103459|TAIR:locus:2182275|TAIR:locus:2131844|TAIR:locus:2195528 Communication:501741973 2023-06-07 AT3G48930 locus:2101278 AT3G48930 part of cytosolic small ribosomal subunit GO:0022627 29019 C cytosol IBA none PANTHER:PTN000078534|MGI:MGI:1351329|UniProtKB:P0AG63|RGD:621026|SGD:S000000252|SGD:S000002432|UniProtKB:P62280 Communication:501741973 2023-06-07 AT3G48930 locus:2101278 AT3G48930 located in cytosol GO:0005829 241 C cytosol HDA none Publication:501776792|PMID:28887381 dszymanski 2019-04-04 AT3G48930 gene:2101277 AT3G48930.1 located in cytoplasm GO:0005737 231 C cytoplasm ISM predicted protein features AnalysisReference:501780126 rkaundal 2018-08-31 AT3G48930 gene:2101277 AT3G48930.1 located in plant-type cell wall GO:0009505 156 C cell wall HDA none NONE Publication:501718077|PMID:16287169 kvanwijk 2021-05-12 AT3G48930 locus:2101278 AT3G48930 located in cytosolic ribosome GO:0022626 29018 C cytosol HDA none NONE Publication:501714975|PMID:15821981 TAIR 2021-04-15 AT3G48930 locus:2101278 AT3G48930 enables mRNA binding GO:0003729 3091 F RNA binding HDA none NONE Publication:501771908|PMID:27729395 tmillar 2021-04-22 AT3G48930 gene:2101277 AT3G48930.1 located in plasmodesma GO:0009506 571 C other cellular components HDA none NONE Publication:501742898|PMID:21533090 maule 2021-04-07 AT3G48930 gene:2101277 AT3G48930.1 located in cytosolic ribosome GO:0022626 29018 C cytosol HDA none NONE Publication:501714975|PMID:15821981 kvanwijk 2021-04-15 AT3G48930 locus:2101278 AT3G48930 acts upstream of or within embryo development ending in seed dormancy GO:0009793 11994 P post-embryonic development NAS Database entries that dont cite a paper (e.g. SwissProt records)

Function-related keywords:

• shoot axis apex ,  root ,  plant embryo ,  flower ,  hypocotyl

Literature:

• Bicistronic and fused monocistronic transcripts are derived from adjacent loci in the Arabidopsis genome.   DOI:  10.1261/rna.7114505 ;  PMID:  15659355
• Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.   DOI:  10.1093/molbev/msq204 ;  PMID:  20736450
• AtGEN1 and AtSEND1, two paralogs in Arabidopsis, possess holliday junction resolvase activity.   DOI:  10.1104/pp.114.237834 ;  PMID:  25037209
• The Structure-Specific Endonucleases MUS81 and SEND1 Are Essential for Telomere Stability in Arabidopsis.   DOI:  10.1105/tpc.15.00898 ;  PMID:  26704385

Sequences: