Gene Details:
- Gene ID: AT3G47390
- Gene Symbol: PHS1, PyrR
- Gene Name: PHOTOSENSITIVE 1, pyrimidine reductase
- Description: cytidine/deoxycytidylate deaminase family protein;(source:Araport11)
- TAIR Accession: locus:2099555
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
Gene Ontology:
- GO:0009507 — located in — chloroplast
- GO:0008703 — enables — 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
- GO:0016799 — enables — hydrolase activity, hydrolyzing N-glycosyl compounds
- GO:0009231 — involved in — riboflavin biosynthetic process
- GO:1901135 — involved in — carbohydrate derivative metabolic process
- GO:0009658 — acts upstream of or within — chloroplast organization
- GO:0046443 — acts upstream of or within — FAD metabolic process
- GO:0009644 — acts upstream of or within — response to high light intensity
- GO:0008835 — enables — diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
- GO:0050661 — enables — NADP binding
Function-related keywords:
- shoot axis apex , leaf lamina base , root , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen
Literature:
- Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. DOI: 10.1074/jbc.M308435200 ; PMID: 14576160
- Starch Granule Size and Morphology of Arabidopsis thaliana Starch-Related Mutants Analyzed during Diurnal Rhythm and Development. DOI: 10.3390/molecules26195859 ; PMID: 34641402
- Carbon pathways during transitory starch degradation in Arabidopsis differentially affect the starch granule number and morphology in the dpe2/phs1 mutant background. DOI: 10.1016/j.plaphy.2022.03.033 ; PMID: 35378390
- Dpe2/phs1 revealed unique starch metabolism with three distinct phases characterized by different starch granule numbers per chloroplast, allowing insights into the control mechanism of granule number regulation by gene co-regulation and metabolic profiling. DOI: 10.3389/fpls.2022.1039534 ; PMID: 36407636
- Tracing the evolution of the plant meiotic molecular machinery. DOI: 10.1007/s00497-022-00456-1 ; PMID: 36646915
Sequences:
cDNA Sequence
- >AT3G47390.2
CTTTTTTTTTTCTTCTTTGACAGTAAACGACGACGTCTCCCTTTTTTTCTTTCTTCGATCTCCTTCTGCCAAACACTCTCTTCTTCTTCTTCTTCAATCTTCTTTCTTCGATCTCTTCTTTTTCAAAATCTCTTCTTTGATTGTGAGAAGCCATAAGTAAAGGTGATTGAAATCTATAATAGGAGCTGCCATTGTGTGTTGAATGGGTATCAAGTTCTTCTTCTAAGTGATCCAAATCCTGCTTCCGATTAGCTCAAATACTTGACACAAAGAGTTCCTGCAAAAAGAGCTCAAAGAGTTTCTCTTTACATAATCCGGTGATGTACTGTCTTTCTTTCCTGTATCAGTTCCAACTCTTTGATTAGGCAAATCGATTCTCTCAATGGCTCTTTCATTTCGAATTTCTTCGTCGTCTCCGTTAATCTGCAGAGCCACTCTCTCAAACGGCGACAACAGTCGTAACTACCACACGACTGATGCCGCTTTTATCCGACGCGCCGCCGATTTGTCCGAAATGTCCGCCGGACTTACTTCACCTCACCCTAATTTCGGCTGTGTAATCGCCACTTCTTCCGGTAAAGTCGCCGGAGAAGGATATCTATACGCTCAAGGTACTAAACCGGCGGAAGCGTTGGCTGTTGAAGCTGCCGGAGAGTTTTCTAGAGGCGCCACTGCTTATTTAAACATGGAGCCTGGTGATTGTCATGGTGACCACACTGCTGTATCTGCTCTTGTTCAGGCAGGAATTGAACGAGTTGTTGTTGGAATAAGGCATCCTTTGCAACATCTTAGAGGCTCTGCGATTCGTGAATTAAGAAGTCATGGTATCGAAGTTAATGTTCTTGGAGAAGACTTTGAGAGTAAAGTTCTTGAGGATGCTCGGAAATCGTGTCTTCTTGTGAATGCTCCTTTGATTCATAGAGCTTGTTCTCGAGTTCCGTTCTCTGTTCTTAAGTATGCCATGACTCTTGATGGTAAGATTGCAGCGAGTAGTGGACATGCAGCATGGATAAGTAGTAAACTCTCTAGAACCCGAGTGTTCGAGTTGCGAGGAGGAAGTGATGCTGTGATAGTTGGAGGAAACACAGTACGCCAAGATGATCCTCGATTGACTGCAAGACACGGACAGGGTCACACCCCTACACGAATTGTGATGACTCAGAGTCTTGATCTTCCTGAGAAAGCTAATCTATGGGATGTCTCGGAAGTATCTACCATAGTTGTTACCCAAAGGGGTGCAAGAAAGAGTTTCCAGAAATTGCTTGCGTCCAAGGGTGTTGAAGTTGTGGAGTTTGACATGTTGAATCCAAGAGAAGTTATGGAATATTTCCATCTCCGTGGATATCTTTCTATACTATGGGAGTGTGGGGGAACATTAGCTGCATCTGCTATATCATCCAGTGTCATCCACAAGGTTGTTGCTTTCGTTGCTCCAAAAATTATCGGTGGGAGTAAAGCACCTTCCCCTGTGGGTGACCTTGGGATGGTAGAGATGACACAAGCATTGAATTTAATTGATGTTTGTTATGAGCAGGTTGGTCCCGACATGCTTGTCAGCGGATTTCTTCAGCCCATACCAGACCTCTTACCTGTTATCCCATCAGAGGATGCAACTGTCGAGATTGACCCCAGTGTTGACCCCTTTGAACCTAGTATCATATTCTTCTACAAAACATGGGACCTCTATGGAAGTTTCTCAAATTTTTCTCCACATCCAATTCGAATGCCCTATGGCGAGGAGAATGATGATTACATGACCTGGTCCAGTGTGGAACATTACTATCAGGCAAACAAGTTTGTTGGGGTCGAAAATCCAAAGGCATATGATTGCGTTGAGAAAATTAGAACAGCTAGAAGTCCAGAGGAGGCAGCTCTGATAGGCAGATCAACACTGAGACAGAAACCTGAACTGGTTCGGAATGATTGGGAAGATGTGAAGATAGAAGTAATGTACAAGGCTTTAAAATGCAAGTTCTCAACTTATCCTCACTTGAAATCAATGTTGCTCTCGACAATTGGAACAGTTCTCGTGGAGGCTTCACCGCACGATCTATTCTGGGGAGGTGGCCGTGAAGGAGAAGGGCTTAACTATCTTGGTCGACTGCTTATGCAGCTTCGTTCTGAGTATCTGGGCGAATCCTCTGTTTCAGCTGAAAAGACTTCTTCGGCCTGATGGATGATGATAGTCTTTCATATTTATTCCAAAAAGTTATCAATAAAACTTTCAGTTTTCCTCAATTTTGACATTTACATTGTTGTAATTCTTTAACCTATATAACATTATTGTAAGTTTGTAACATTATGATAGTTTTCCTAGACCATTTGATTCACATTAACTCATACTGAGTATTTTAAATGGTAACGGTAGAGTTTTTATTTGCTT - >AT3G47390.1
CTTTTTTTTTTCTTCTTTGACAGTAAACGACGACGTCTCCCTTTTTTTCTTTCTTCGATCTCCTTCTGCCAAACACTCTCTTCTTCTTCTTCTTCAATCTTCTTTCTTCGATCTCTTCTTTTTCAAAATCTCTTCTTTGATTGTGAGAAGCCATAAGTAAAGGTGATTGAAATCTATAATAGGAGCTGCCATTGTGTGTTGAATGGGTATCAAGTTCTTCTTCTAAGTGATCCAAATCCTGCTTCCGATTAGCTCAAATACTTGACACAAAGAGTTCCTGCAAAAAGAGCTCAAAGAGTTTCTCTTTACATAATCCGGTGATGTACTGTCTTTCTTTCCTGTATCAGTTCCAACTCTTTGATTAGGCAAATCGATTCTCTCAATGGCTCTTTCATTTCGAATTTCTTCGTCGTCTCCGTTAATCTGCAGAGCCACTCTCTCAAACGGCGACAACAGTCGTAACTACCACACGACTGATGCCGCTTTTATCCGACGCGCCGCCGATTTGTCCGAAATGTCCGCCGGACTTACTTCACCTCACCCTAATTTCGGCTGTGTAATCGCCACTTCTTCCGGTAAAGTCGCCGGAGAAGGATATCTATACGCTCAAGGTACTAAACCGGCGGAAGCGTTGGCTGTTGAAGCTGCCGGAGAGTTTTCTAGAGGCGCCACTGCTTATTTAAACATGGAGCCTGGTGATTGTCATGGTGACCACACTGCTGTATCTGCTCTTGTTCAGGCAGGAATTGAACGAGTTGTTGTTGGAATAAGGCATCCTTTGCAACATCTTAGAGGCTCTGCGATTCGTGAATTAAGAAGTCATGGTATCGAAGTTAATGTTCTTGGAGAAGACTTTGAGAGTAAAGTTCTTGAGGATGCTCGGAAATCGTGTCTTCTTGTGAATGCTCCTTTGATTCATAGAGCTTGTTCTCGAGTTCCGTTCTCTGTTCTTAAGTATGCCATGACTCTTGATGGTAAGATTGCAGCGAGTAGTGGACATGCAGCATGGATAAGTAGTAAACTCTCTAGAACCCGAGTGTTCGAGTTGCGAGGAGGAAGTGATGCTGTGATAGTTGGAGGAAACACAGTACGCCAAGATGATCCTCGATTGACTGCAAGACACGGACAGGGTCACACCCCTACACGAATTGTGATGACTCAGAGTCTTGATCTTCCTGAGAAAGCTAATCTATGGGATGTCTCGGAAGTATCTACCATAGTTGTTACCCAAAGGGGTGCAAGAAAGAGTTTCCAGAAATTGCTTGCGTCCAAGGGTGTTGAAGTTGTGGAGTTTGACATGTTGAATCCAAGAGAAGTTATGGAATATTTCCATCTCCGTGGATATCTTTCTATACTATGGGAGTGTGGGGGAACATTAGCTGCATCTGCTATATCATCCAGTGTCATCCACAAGGTTGTTGCTTTCGTTGCTCCAAAAATTATCGGTGGGAGTAAAGCACCTTCCCCTGTGGGTGACCTTGGGATGGTAGAGATGACACAAGCATTGAATTTAATTGATGTTTGTTATGAGCAGGTTGGTCCCGACATGCTTGTCAGCGGATTTCTTCAGCCCATACCAGACCTCTTACCTGTTATCCCATCAGAGGATGCAACTGTCGAGATTGACCCCAGTGTTGACCCCTTTGAACCTAGTATCATATTCTTCTACAAAACATGGGACCTCTATGGAAGTTTCTCAAATTTTTCTCCACATCCAATTCGAATGCCCTATGGCGAGGAGAATGATGATTACATGACCTGGTCCAGTGTGGAACATTACTATCAGGCAAACAAGTTTGTTGGGGTCGAAAATCCAAAGGCATATGATTGCGTTGAGAAAATTAGAACAGCTAGAAGTCCAGAGGAGGCAGCTCTGATAGGCAGATCAACACTGAGACAGAAACCTGAACTGGTTCGGAATGATTGGGAAGATGTGAAGATAGAAGTAATGTACAAGGCTTTAAAATGCAAGTTCTCAACTTATCCTCACTTGAAATCAATGTTGCTCTCGACAATTGGAACAGTTCTCGTGGAGGCTTCACCGCACGATCTATTCTGGGGAGGTGGCCGTGAAGGAGAAGGGCTTAACTATCTTGGTCGACTGCTTATGCAGCTTCGTTCTGAGTATCTGGGCGAATCCTCTGTTTCAGCTGAAAAGACTTCTTCGGCCTGATGGATGATGATAGTCTTTCATATTTATTCCAAAAAGTTATCAATAAAACTTTCAGTTTTCCTCAATTTTGACATTTACATTGTTGTAATTCTTTAACCTATATAACATTATTGTAAGTTTGTAACATTATGATAGTTTTCCTAGACCATTTGATTCACATTAACTCATACTGAGTATTTTAAATGGTAACGGTAGAGTTTTTATTTGCTT
CDS Sequence
- >AT3G47390.2
ATGGCTCTTTCATTTCGAATTTCTTCGTCGTCTCCGTTAATCTGCAGAGCCACTCTCTCAAACGGCGACAACAGTCGTAACTACCACACGACTGATGCCGCTTTTATCCGACGCGCCGCCGATTTGTCCGAAATGTCCGCCGGACTTACTTCACCTCACCCTAATTTCGGCTGTGTAATCGCCACTTCTTCCGGTAAAGTCGCCGGAGAAGGATATCTATACGCTCAAGGTACTAAACCGGCGGAAGCGTTGGCTGTTGAAGCTGCCGGAGAGTTTTCTAGAGGCGCCACTGCTTATTTAAACATGGAGCCTGGTGATTGTCATGGTGACCACACTGCTGTATCTGCTCTTGTTCAGGCAGGAATTGAACGAGTTGTTGTTGGAATAAGGCATCCTTTGCAACATCTTAGAGGCTCTGCGATTCGTGAATTAAGAAGTCATGGTATCGAAGTTAATGTTCTTGGAGAAGACTTTGAGAGTAAAGTTCTTGAGGATGCTCGGAAATCGTGTCTTCTTGTGAATGCTCCTTTGATTCATAGAGCTTGTTCTCGAGTTCCGTTCTCTGTTCTTAAGTATGCCATGACTCTTGATGGTAAGATTGCAGCGAGTAGTGGACATGCAGCATGGATAAGTAGTAAACTCTCTAGAACCCGAGTGTTCGAGTTGCGAGGAGGAAGTGATGCTGTGATAGTTGGAGGAAACACAGTACGCCAAGATGATCCTCGATTGACTGCAAGACACGGACAGGGTCACACCCCTACACGAATTGTGATGACTCAGAGTCTTGATCTTCCTGAGAAAGCTAATCTATGGGATGTCTCGGAAGTATCTACCATAGTTGTTACCCAAAGGGGTGCAAGAAAGAGTTTCCAGAAATTGCTTGCGTCCAAGGGTGTTGAAGTTGTGGAGTTTGACATGTTGAATCCAAGAGAAGTTATGGAATATTTCCATCTCCGTGGATATCTTTCTATACTATGGGAGTGTGGGGGAACATTAGCTGCATCTGCTATATCATCCAGTGTCATCCACAAGGTTGTTGCTTTCGTTGCTCCAAAAATTATCGGTGGGAGTAAAGCACCTTCCCCTGTGGGTGACCTTGGGATGGTAGAGATGACACAAGCATTGAATTTAATTGATGTTTGTTATGAGCAGGTTGGTCCCGACATGCTTGTCAGCGGATTTCTTCAGCCCATACCAGACCTCTTACCTGTTATCCCATCAGAGGATGCAACTGTCGAGATTGACCCCAGTGTTGACCCCTTTGAACCTAGTATCATATTCTTCTACAAAACATGGGACCTCTATGGAAGTTTCTCAAATTTTTCTCCACATCCAATTCGAATGCCCTATGGCGAGGAGAATGATGATTACATGACCTGGTCCAGTGTGGAACATTACTATCAGGCAAACAAGTTTGTTGGGGTCGAAAATCCAAAGGCATATGATTGCGTTGAGAAAATTAGAACAGCTAGAAGTCCAGAGGAGGCAGCTCTGATAGGCAGATCAACACTGAGACAGAAACCTGAACTGGTTCGGAATGATTGGGAAGATGTGAAGATAGAAGTAATGTACAAGGCTTTAAAATGCAAGTTCTCAACTTATCCTCACTTGAAATCAATGTTGCTCTCGACAATTGGAACAGTTCTCGTGGAGGCTTCACCGCACGATCTATTCTGGGGAGGTGGCCGTGAAGGAGAAGGGCTTAACTATCTTGGTCGACTGCTTATGCAGCTTCGTTCTGAGTATCTGGGCGAATCCTCTGTTTCAGCTGAAAAGACTTCTTCGGCCTGA - >AT3G47390.1
ATGGCTCTTTCATTTCGAATTTCTTCGTCGTCTCCGTTAATCTGCAGAGCCACTCTCTCAAACGGCGACAACAGTCGTAACTACCACACGACTGATGCCGCTTTTATCCGACGCGCCGCCGATTTGTCCGAAATGTCCGCCGGACTTACTTCACCTCACCCTAATTTCGGCTGTGTAATCGCCACTTCTTCCGGTAAAGTCGCCGGAGAAGGATATCTATACGCTCAAGGTACTAAACCGGCGGAAGCGTTGGCTGTTGAAGCTGCCGGAGAGTTTTCTAGAGGCGCCACTGCTTATTTAAACATGGAGCCTGGTGATTGTCATGGTGACCACACTGCTGTATCTGCTCTTGTTCAGGCAGGAATTGAACGAGTTGTTGTTGGAATAAGGCATCCTTTGCAACATCTTAGAGGCTCTGCGATTCGTGAATTAAGAAGTCATGGTATCGAAGTTAATGTTCTTGGAGAAGACTTTGAGAGTAAAGTTCTTGAGGATGCTCGGAAATCGTGTCTTCTTGTGAATGCTCCTTTGATTCATAGAGCTTGTTCTCGAGTTCCGTTCTCTGTTCTTAAGTATGCCATGACTCTTGATGGTAAGATTGCAGCGAGTAGTGGACATGCAGCATGGATAAGTAGTAAACTCTCTAGAACCCGAGTGTTCGAGTTGCGAGGAGGAAGTGATGCTGTGATAGTTGGAGGAAACACAGTACGCCAAGATGATCCTCGATTGACTGCAAGACACGGACAGGGTCACACCCCTACACGAATTGTGATGACTCAGAGTCTTGATCTTCCTGAGAAAGCTAATCTATGGGATGTCTCGGAAGTATCTACCATAGTTGTTACCCAAAGGGGTGCAAGAAAGAGTTTCCAGAAATTGCTTGCGTCCAAGGGTGTTGAAGTTGTGGAGTTTGACATGTTGAATCCAAGAGAAGTTATGGAATATTTCCATCTCCGTGGATATCTTTCTATACTATGGGAGTGTGGGGGAACATTAGCTGCATCTGCTATATCATCCAGTGTCATCCACAAGGTTGTTGCTTTCGTTGCTCCAAAAATTATCGGTGGGAGTAAAGCACCTTCCCCTGTGGGTGACCTTGGGATGGTAGAGATGACACAAGCATTGAATTTAATTGATGTTTGTTATGAGCAGGTTGGTCCCGACATGCTTGTCAGCGGATTTCTTCAGCCCATACCAGACCTCTTACCTGTTATCCCATCAGAGGATGCAACTGTCGAGATTGACCCCAGTGTTGACCCCTTTGAACCTAGTATCATATTCTTCTACAAAACATGGGACCTCTATGGAAGTTTCTCAAATTTTTCTCCACATCCAATTCGAATGCCCTATGGCGAGGAGAATGATGATTACATGACCTGGTCCAGTGTGGAACATTACTATCAGGCAAACAAGTTTGTTGGGGTCGAAAATCCAAAGGCATATGATTGCGTTGAGAAAATTAGAACAGCTAGAAGTCCAGAGGAGGCAGCTCTGATAGGCAGATCAACACTGAGACAGAAACCTGAACTGGTTCGGAATGATTGGGAAGATGTGAAGATAGAAGTAATGTACAAGGCTTTAAAATGCAAGTTCTCAACTTATCCTCACTTGAAATCAATGTTGCTCTCGACAATTGGAACAGTTCTCGTGGAGGCTTCACCGCACGATCTATTCTGGGGAGGTGGCCGTGAAGGAGAAGGGCTTAACTATCTTGGTCGACTGCTTATGCAGCTTCGTTCTGAGTATCTGGGCGAATCCTCTGTTTCAGCTGAAAAGACTTCTTCGGCCTGA
Protein Sequence
- >AT3G47390.2
MALSFRISSSSPLICRATLSNGDNSRNYHTTDAAFIRRAADLSEMSAGLTSPHPNFGCVIATSSGKVAGEGYLYAQGTKPAEALAVEAAGEFSRGATAYLNMEPGDCHGDHTAVSALVQAGIERVVVGIRHPLQHLRGSAIRELRSHGIEVNVLGEDFESKVLEDARKSCLLVNAPLIHRACSRVPFSVLKYAMTLDGKIAASSGHAAWISSKLSRTRVFELRGGSDAVIVGGNTVRQDDPRLTARHGQGHTPTRIVMTQSLDLPEKANLWDVSEVSTIVVTQRGARKSFQKLLASKGVEVVEFDMLNPREVMEYFHLRGYLSILWECGGTLAASAISSSVIHKVVAFVAPKIIGGSKAPSPVGDLGMVEMTQALNLIDVCYEQVGPDMLVSGFLQPIPDLLPVIPSEDATVEIDPSVDPFEPSIIFFYKTWDLYGSFSNFSPHPIRMPYGEENDDYMTWSSVEHYYQANKFVGVENPKAYDCVEKIRTARSPEEAALIGRSTLRQKPELVRNDWEDVKIEVMYKALKCKFSTYPHLKSMLLSTIGTVLVEASPHDLFWGGGREGEGLNYLGRLLMQLRSEYLGESSVSAEKTSSA - >AT3G47390.1
MALSFRISSSSPLICRATLSNGDNSRNYHTTDAAFIRRAADLSEMSAGLTSPHPNFGCVIATSSGKVAGEGYLYAQGTKPAEALAVEAAGEFSRGATAYLNMEPGDCHGDHTAVSALVQAGIERVVVGIRHPLQHLRGSAIRELRSHGIEVNVLGEDFESKVLEDARKSCLLVNAPLIHRACSRVPFSVLKYAMTLDGKIAASSGHAAWISSKLSRTRVFELRGGSDAVIVGGNTVRQDDPRLTARHGQGHTPTRIVMTQSLDLPEKANLWDVSEVSTIVVTQRGARKSFQKLLASKGVEVVEFDMLNPREVMEYFHLRGYLSILWECGGTLAASAISSSVIHKVVAFVAPKIIGGSKAPSPVGDLGMVEMTQALNLIDVCYEQVGPDMLVSGFLQPIPDLLPVIPSEDATVEIDPSVDPFEPSIIFFYKTWDLYGSFSNFSPHPIRMPYGEENDDYMTWSSVEHYYQANKFVGVENPKAYDCVEKIRTARSPEEAALIGRSTLRQKPELVRNDWEDVKIEVMYKALKCKFSTYPHLKSMLLSTIGTVLVEASPHDLFWGGGREGEGLNYLGRLLMQLRSEYLGESSVSAEKTSSA