Gene Details:

• Gene ID: AT3G43190
• Gene Symbol: ATSUS4, SUS4
• Gene Name: ARABIDOPSIS THALIANA SUCROSE SYNTHASE 4, sucrose synthase 4
• Description: sucrose synthase 4;(source:Araport11)
• TAIR Accession: locus:2084756
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G43190.1     AT3G43190.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0000056  — flower bud — floral bud (exact), yema floral (Spanish, exact), 花芽 (Japanese, exact)
• PO:0009001  — fruit — frucht (exact, German), fruto (exact, Spanish), 果実 (exact, Japanese), coenocarp (narrow), syncarp (narrow), aggregate fruit (broad), compound fruit (broad), dehiscent fruit (broad), diaspore (broad), indehiscent fruit (broad), multiple fruit (broad), propagule (broad)
• PO:0009010  — seed — semilla (Spanish, exact), 種子 (Japanese, exact), pyrene (narrow), diaspore (broad)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)

Gene Ontology:

• GO:0001666  — involved in — response to hypoxia
• GO:0071456  — acts upstream of or within — cellular response to hypoxia
• GO:0016757  — enables — glycosyltransferase activity
• GO:0005985  — involved in — sucrose metabolic process
• GO:0016157  — enables — sucrose synthase activity
• GO:0005773  — located in — vacuole

Germplasm Phenotype:

• CS2109806  — susceptible to waterlogging (SUS1 and SUS4 are together necessary for tolerance of hypoxic conditions)
• sus1 sus4  — The activity of SUS was reduced to 10% of wild-type levels in leaves of the mutant, and was undetectable (reduced to less than 10% of wild-type levels) in roots. The activity of invertase was unaffected in roots of this mutant, but in leaves neutral invertase activity was elevated by about 40%.
• sus1 sus4  — The double mutant line was much more severely affected by flooding. After the 4 days of flooding, root weight had increased by only 44% (compared to 72% for wild type), and there was not statistically significant gain in root weight in the 3 days following flooding. At the end of the 7-day period, the flooding treatment had reduced the gain in root weight by 71% relative to unflooded control plants (compared to 33% for wild type).
• sus1 sus4  — The sugar content of leaves was substantially higher than that of the wild-type control. This was most pronounced at the end of the night, when glucose and fructose were almost ninefold higher in mutant than wild-type leaves and sucrose was more than twofold higher.
• sus1 sus4  — When grown in soil, the double mutant line was not obviously different from wild-type controls. However, when grown hydroponically, the mutants grew considerably more slowly.
• sus4  — No visible phenotype.
• sus4  — The amounts of glucose, fructose, sucrose, cellulose (roots) and starch in the mutant were not statistically significantly different from those of the equivalent wild-type lines grown under the same conditions at the same time.

Function-related keywords:

• shoot axis apex ,  root ,  plant embryo ,  vascular leaf ,  flower ,  hypocotyl ,  leaf apex ,  flower bud ,  fruit ,  root ,  seed ,  flower ,  stem ,  inflorescence flower pedicel

Literature:

• Expression profile analysis of the low-oxygen response in Arabidopsis root cultures.   DOI:  10.1105/tpc.004747 ;  PMID:  12368499
• Toxicity of free proline revealed in an arabidopsis T-DNA-tagged mutant deficient in proline dehydrogenase.   DOI:  10.1093/pcp/pcg066 ;  PMID:  12773641
• Structure and expression profile of the sucrose synthase multigene family in Arabidopsis.   DOI:  10.1093/jxb/erh047 ;  PMID:  14739263
• Genomic identification of direct target genes of LEAFY.   DOI:  10.1073/pnas.0307842100 ;  PMID:  14736918
• Transcriptional profiling of genes responsive to abscisic acid and gibberellin in rice: phenotyping and comparative analysis between rice and Arabidopsis.   DOI:  10.1152/physiolgenomics.00201.2003 ;  PMID:  14982972
• Large-scale characterization of integral proteins from Arabidopsis vacuolar membrane by two-dimensional liquid chromatography.   DOI:  10.1002/pmic.200300607 ;  PMID:  14760709
• Linking protein fractionation with multidimensional monolithic reversed-phase peptide chromatography/mass spectrometry enhances protein identification from complex mixtures even in the presence of abundant proteins.   DOI:  10.1002/rcm.1376 ;  PMID:  15052571
• Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications.   DOI:  10.1101/gr.2544504 ;  PMID:  15489341
• Global transcription profiling reveals comprehensive insights into hypoxic response in Arabidopsis.   DOI:  10.1104/pp.104.055475 ;  PMID:  15734912
• A genome-wide analysis of the effects of sucrose on gene expression in Arabidopsis seedlings under anoxia.   DOI:  10.1104/pp.104.057299 ;  PMID:  15734908
• The use of microarrays to study the anaerobic response in Arabidopsis.   DOI:  10.1093/aob/mci218 ;  PMID:  16033780
• Stress-induced protein S-glutathionylation in Arabidopsis.   DOI:  10.1104/pp.104.058917 ;  PMID:  16055689
• Genome-wide analysis of transcript abundance and translation in Arabidopsis seedlings subjected to oxygen deprivation.   DOI:  10.1093/aob/mci217 ;  PMID:  16081496
• Biosynthesis of cellulose-enriched tension wood in Populus: global analysis of transcripts and metabolites identifies biochemical and developmental regulators in secondary wall biosynthesis.   DOI:  10.1111/j.1365-313X.2005.02584.x ;  PMID:  16367961
• Monitoring expression profiles of Arabidopsis genes during cold acclimation and deacclimation using DNA microarrays.   DOI:  10.1007/s10142-005-0014-z ;  PMID:  16463051
• The Arabidopsis thaliana transcriptome in response to Agrobacterium tumefaciens.   DOI:  10.1094/MPMI-19-0665 ;  PMID:  16776300
• Response diversity of Arabidopsis thaliana ecotypes in elevated [CO2] in the field.   DOI:  10.1007/s11103-006-9041-y ;  PMID:  16941220
• The Populus homeobox gene ARBORKNOX1 reveals overlapping mechanisms regulating the shoot apical meristem and the vascular cambium.   DOI:  10.1007/s11103-006-0059-y ;  PMID:  16927204
• A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress.   DOI:  10.1128/MCB.01063-06 ;  PMID:  17030626
• An integrated view of gene expression and solute profiles of Arabidopsis tumors: a genome-wide approach.   DOI:  10.1105/tpc.106.044743 ;  PMID:  17172353
• Analysis of the sucrose synthase gene family in Arabidopsis.   DOI:  10.1111/j.1365-313X.2006.03011.x ;  PMID:  17257168
• Localization of sucrose synthase in developing seed and siliques of Arabidopsis thaliana reveals diverse roles for SUS during development.   DOI:  10.1093/jxb/ern180 ;  PMID:  18635527
• Integrative analyses of genetic variation in enzyme activities of primary carbohydrate metabolism reveal distinct modes of regulation in Arabidopsis thaliana.   DOI:  10.1186/gb-2008-9-8-r129 ;  PMID:  18710526
• Normal growth of Arabidopsis requires cytosolic invertase but not sucrose synthase.   DOI:  10.1073/pnas.0900689106 ;  PMID:  19470642
• Sucrose synthase activity in the sus1/sus2/sus3/sus4 Arabidopsis mutant is sufficient to support normal cellulose and starch production.   DOI:  10.1073/pnas.1117099109 ;  PMID:  22184213
• A sensitive method for confocal fluorescence microscopic visualization of starch granules in iodine stained samples.   DOI:  10.4161/psb.21370 ;  PMID:  22899048
• Both AtrbohD and AtrbohF are essential for mediating responses to oxygen deficiency in Arabidopsis.   DOI:  10.1007/s00299-017-2128-x ;  PMID:  28337518
• Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress.   DOI:  10.1038/s41467-019-12045-4 ;  PMID:  31488841
• Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress.   DOI:  10.1105/tpc.19.00463 ;  PMID:  31519798
• Arabidopsis sucrose synthase localization indicates a primary role in sucrose translocation in phloem.   DOI:  10.1093/jxb/erz539 ;  PMID:  31805187
• The ubiquitin E3 ligase SR1 modulates the submergence response by degrading phosphorylated WRKY33 in Arabidopsis.   DOI:  10.1093/plcell/koab062 ;  PMID:  33616649
• An Arabidopsis Prolyl 4 Hydroxylase Is Involved in the Low Oxygen Response.   DOI:  10.3389/fpls.2021.637352 ;  PMID:  33790927
• Sucrose synthase activity is not required for cellulose biosynthesis in Arabidopsis.   DOI:  10.1111/tpj.15752 ;  PMID:  35362151
• Large-scale characterization of integral proteins from Arabidopsis vacuolar membrane by two-dimensional liquid chromatography.   DOI:  10.1002/pmic.200300607 ;  PMID:  14760709
• A genome-wide analysis of the effects of sucrose on gene expression in Arabidopsis seedlings under anoxia.   DOI:  10.1104/pp.104.057299 ;  PMID:  15734908
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890

Sequences: