Gene Details:

• Gene ID: AT3G30775
• Gene Symbol: AT-POX, ATPDH, ATPOX, ERD5, PDH1, PRO1, PRODH
• Gene Name: ARABIDOPSIS THALIANA PROLINE OXIDASE, EARLY RESPONSIVE TO DEHYDRATION 5, proline dehydrogenase 1, PROLINE DEHYDROGENASE
• Description: Methylenetetrahydrofolate reductase family protein;(source:Araport11)
• TAIR Accession: locus:2089706
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G30775.1     AT3G30775.2

Plant Ontology Annotations:

• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)

Gene Ontology:

• GO:0071949  — enables — FAD binding
• GO:0006562  — acts upstream of or within — proline catabolic process
• GO:0042742  — acts upstream of or within — defense response to bacterium
• GO:0010133  — involved in — proline catabolic process to glutamate
• GO:0009414  — acts upstream of or within — response to water deprivation
• GO:0071456  — acts upstream of or within — cellular response to hypoxia
• GO:0005739  — located in — mitochondrion
• GO:0004657  — enables — proline dehydrogenase activity
• GO:0005739  — is active in — mitochondrion
• GO:0006979  — acts upstream of or within — response to oxidative stress

Germplasm Phenotype:

• CS69622  — Blocked in proline catabolism. Under low water potential conditions, decreased root elongation and decreased dry weight.
• pdh1-2  — Decreased root elongation and decreased dry weight for plants grown under low water potential conditions.
• pdh1-2  — Response to lower water potential results in an NADP/NADPH ratio that is altered (lower) with respect to wild type. However, the NAD/NADH ratio remains the same.

Function-related keywords:

• vascular leaf ,  stem ,  shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  pollen tube cell ,  pollen

Literature:

• Aluminum induces oxidative stress genes in Arabidopsis thaliana.   DOI:  10.1104/pp.116.1.409 ;  PMID:  9449849
• Cloning of cDNAs for genes that are early-responsive to dehydration stress (ERDs) in Arabidopsis thaliana L.: identification of three ERDs as HSP cognate genes.   DOI:  10.1007/BF00028874 ;  PMID:  8075396
• and hypoosmolarity-responsive expression of the ProDH gene encoding proline dehydrogenase in Arabidopsis.   DOI:  10.1104/pp.009993 ;  PMID:  12376638
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Differential patterns of reactive oxygen species and antioxidative mechanisms during atrazine injury and sucrose-induced tolerance in Arabidopsis thaliana plantlets.   DOI:  10.1186/1471-2229-9-28 ;  PMID:  19284649
• Nitric reductase-dependent nitric oxide production is involved in cold acclimation and freezing tolerance in Arabidopsis.   DOI:  10.1104/pp.109.140996 ;  PMID:  19710235
• Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.   DOI:  10.1093/molbev/msq204 ;  PMID:  20736450
• Proline induces calcium-mediated oxidative burst and salicylic acid signaling.   DOI:  10.1007/s00726-010-0757-2 ;  PMID:  20890619
• Mechanisms independent of abscisic acid (ABA) or proline feedback have a predominant role in transcriptional regulation of proline metabolism during low water potential and stress recovery.   DOI:  10.1111/j.1365-3040.2010.02188.x ;  PMID:  20545884
• Essential role of tissue-specific proline synthesis and catabolism in growth and redox balance at low water potential.   DOI:  10.1104/pp.111.183210 ;  PMID:  21791601
• Transition of chromatin status during the process of recovery from drought stress in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcs053 ;  PMID:  22505693
• Transcriptional and metabolomic analysis of Ascophyllum nodosum mediated freezing tolerance in Arabidopsis thaliana.   DOI:  10.1186/1471-2164-13-643 ;  PMID:  23171218
• A Medicago truncatula EF-hand family gene, MtCaMP1, is involved in drought and salt stress tolerance.   DOI:  10.1371/journal.pone.0058952 ;  PMID:  23593126
• Arabidopsis AtbHLH112 regulates the expression of genes involved in abiotic stress tolerance by binding to their E-box and GCG-box motifs.   DOI:  10.1111/nph.13387 ;  PMID:  25827016
• Dynamic proline metabolism: importance and regulation in water limited environments.   DOI:  10.3389/fpls.2015.00484 ;  PMID:  26161086
• Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.   DOI:  10.1111/nph.14242 ;  PMID:  27768815
• Proline Coordination with Fatty Acid Synthesis and Redox Metabolism of Chloroplast and Mitochondria.   DOI:  10.1104/pp.16.01097 ;  PMID:  27512016
• MRF Family Genes Are Involved in Translation Control, Especially under Energy-Deficient Conditions, and Their Expression and Functions Are Modulated by the TOR Signaling Pathway.   DOI:  10.1105/tpc.17.00563 ;  PMID:  29084871
• Snf1-RELATED KINASE1-Controlled C/S(1)-bZIP Signaling Activates Alternative Mitochondrial Metabolic Pathways to Ensure Plant Survival in Extended Darkness.   DOI:  10.1105/tpc.17.00414 ;  PMID:  29348240
• SELENOPROTEIN O is a chloroplast protein involved in ROS scavenging and its absence increases dehydration tolerance in Arabidopsis thaliana.   DOI:  10.1016/j.plantsci.2018.02.023 ;  PMID:  29576081
• DFR1-Mediated Inhibition of Proline Degradation Pathway Regulates Drought and Freezing Tolerance in Arabidopsis.   DOI:  10.1016/j.celrep.2018.04.011 ;  PMID:  29949777
• Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress.   DOI:  10.1105/tpc.19.00463 ;  PMID:  31519798
• Light Control of Salt-Induced Proline Accumulation Is Mediated by ELONGATED HYPOCOTYL 5 in Arabidopsis.   DOI:  10.3389/fpls.2019.01584 ;  PMID:  31921239
• 2-oxoglutarate-dependent dioxygenases: A renaissance in attention for ascorbic acid in plants.   DOI:  10.1371/journal.pone.0242833 ;  PMID:  33290424
• Interplay between Proline Metabolism and ROS in the Fine Tuning of Root-Meristem Size in Arabidopsis.   DOI:  10.3390/plants11111512 ;  PMID:  35684285
• Evidence that differential gene expression between the halophyte, Thellungiella halophila, and Arabidopsis thaliana is responsible for higher levels of the compatible osmolyte proline and tight control of Na+ uptake in T. halophila.   DOI:  10.1111/j.1365-3040.2006.01502.x ;  PMID:  17080945
• Altered ABA, proline and hydrogen peroxide in an Arabidopsis glutamate:glyoxylate aminotransferase mutant.   DOI:  10.1007/s11103-007-9145-z ;  PMID:  17318317

Sequences: