Gene Details:

• Gene ID: AT3G30180
• Gene Symbol: BR6OX2, CYP85A2
• Gene Name: brassinosteroid-6-oxidase 2
• Description: brassinosteroid-6-oxidase 2;(source:Araport11)
• TAIR Accession: locus:2098802
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G30180.1

Plant Ontology Annotations:

• PO:0020144  — apical meristem — AM (exact), meristema apical (Spanish, exact), 頂端分裂組織 (Japanese, exact), primary meristem (related), promeristem (broad)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)

Gene Ontology:

• GO:0016132  — involved in — brassinosteroid biosynthetic process
• GO:0009416  — involved in — response to light stimulus
• GO:0102734  — enables — brassinolide synthase activity
• GO:0020037  — enables — heme binding
• GO:0004497  — enables — monooxygenase activity
• GO:0016132  — acts upstream of or within — brassinosteroid biosynthetic process
• GO:0018343  — involved in — protein farnesylation
• GO:0005783  — located in — endoplasmic reticulum
• GO:0005506  — enables — iron ion binding
• GO:0005739  — located in — mitochondrion
• GO:0010268  — involved in — brassinosteroid homeostasis
• GO:0016125  — involved in — sterol metabolic process
• GO:0007275  — involved in — multicellular organism development

Germplasm Phenotype:

• SALK_056270  — weak dwarf phenotype during early vegetative development and a reduced fertility after bolting, although the final plant height appears normal
• SALK_129352  — weak dwarf phenotype during early vegetative development and a reduced fertility after bolting, although the final plant height appears normal
• cyp85a2-3  — weak dwarf phenotype during early vegetative development and a reduced fertility after bolting, although the final plant height appears normal
• cyp86a1-1/cyp85a2-2  — severe dwarfs that are reminiscent of the known strong brassinosteroid-deficient mutants; treatment with brassinolide at 100 nM restored the double mutant phenotype nearly fully to WT but castasterone at the same concentration only partially rescued the phenotype

Function-related keywords:

• apical meristem ,  shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  pollen tube cell ,  pollen

Literature:

• Rapid identification of Arabidopsis insertion mutants by non-radioactive detection of T-DNA tagged genes.   DOI:  10.1046/j.1365-313x.2002.01416.x ;  PMID:  12383089
• Microarray analysis of genes that respond to gamma-irradiation in Arabidopsis.   DOI:  10.1021/jf0486895 ;  PMID:  15713015
• Leucine-rich repeat receptor-like kinase1 is a key membrane-bound regulator of abscisic acid early signaling in Arabidopsis.   DOI:  10.1105/tpc.104.027474 ;  PMID:  15772289
• The Arabidopsis group 1 LATE EMBRYOGENESIS ABUNDANT protein ATEM6 is required for normal seed development.   DOI:  10.1104/pp.105.072967 ;  PMID:  16361514
• Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis.   DOI:  10.1371/journal.pbio.0040143 ;  PMID:  16640459
• Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.   DOI:  10.1016/j.cell.2006.05.050 ;  PMID:  16901781
• The Arabidopsis E3 SUMO ligase SIZ1 regulates plant growth and drought responses.   DOI:  10.1105/tpc.106.049981 ;  PMID:  17905899
• Stamen abscission zone transcriptome profiling reveals new candidates for abscission control: enhanced retention of floral organs in transgenic plants overexpressing Arabidopsis ZINC FINGER PROTEIN2.   DOI:  10.1104/pp.107.110908 ;  PMID:  18192438
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Synergistic disruptions in seuss cyp85A2 double mutants reveal a role for brassinolide synthesis during gynoecium and ovule development.   DOI:  10.1186/1471-2229-10-198 ;  PMID:  20836864
• Biosynthesis of a cholesterol-derived brassinosteroid, 28-norcastasterone, in Arabidopsis thaliana.   DOI:  10.1093/jxb/err354 ;  PMID:  22170941
• and PIF4-controlled plant growth: a coincidence mechanism directly integrates a hormone signaling network into the photoperiodic control of plant architectures in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcs137 ;  PMID:  23037003
• Elongator Is Required for Root Stem Cell Maintenance by Regulating SHORTROOT Transcription.   DOI:  10.1104/pp.18.00534 ;  PMID:  30401723
• Light Activates Brassinosteroid Biosynthesis to Promote Hook Opening and Petiole Development in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcaa053 ;  PMID:  32333772
• HBI1 acts downstream of ERECTA and SWR1 in regulating inflorescence architecture through the activation of the brassinosteroid and auxin signaling pathways.   DOI:  10.1111/nph.16840 ;  PMID:  32746499
• Protein farnesylation negatively regulates brassinosteroid signaling via reducing BES1 stability in Arabidopsis thaliana.   DOI:  10.1111/jipb.13093 ;  PMID:  33764637
• Arabidopsis NF-YCs play dual roles in repressing brassinosteroid biosynthesis and signaling during light-regulated hypocotyl elongation.   DOI:  10.1093/plcell/koab112 ;  PMID:  33871651
• Boron deficiency-induced root growth inhibition is mediated by brassinosteroid signalling regulation in Arabidopsis.   DOI:  10.1111/tpj.15311 ;  PMID:  33964043
• Endogenous level of abscisic acid down-regulated by brassinosteroids signaling via BZR1 to control the growth of Arabidopsis thaliana.   DOI:  10.1080/15592324.2021.1926130 ;  PMID:  33980131
• Gene co-expression network analysis identifies BEH3 as a stabilizer of secondary vascular development in Arabidopsis.   DOI:  10.1093/plcell/koab151 ;  PMID:  34059919

Sequences: