Gene Details:

• Gene ID: AT3G20840
• Gene Symbol: AtPLT1, PLT1
• Gene Name: PLETHORA 1, PLETHORA 1
• Description: Integrase-type DNA-binding superfamily protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G20840.1

Plant Ontology Annotations:

• PO:0005052  — plant callus — callo (Spanish, exact), portion of plant callus tissue (exact), 植物カルス (Japanese, exact), callus (broad)

Germplasm Phenotype:

• plt1-1  — The mutation causes extra cells in the columella root cap and the QC.
• plt1-1/plt2-2  — Short roots due to premature stem cell differentiation. Increased telomere length likely resulting from fewer replicative stem cell divisions prior to differentiation.
• plt1-2  — The mutation causes extra cells in the columella root cap and the QC.
• plt3-1/plt2-2/plt1-4  — Rootless.Embryonic root differentiates 3 days after germination. Adventitious roots arrest 6 days after germination.
• ptl1-4  — sensitive to abscisic acid (ABA)

Function-related keywords:

• plant callus

Literature:

• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The PLETHORA genes mediate patterning of the Arabidopsis root stem cell niche.   DOI:  10.1016/j.cell.2004.09.018 ;  PMID:  15454085
• The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis roots.   DOI:  10.1038/nature03184 ;  PMID:  15635403
• A molecular framework for plant regeneration.   DOI:  10.1126/science.1121790 ;  PMID:  16424342
• Cytokinins determine Arabidopsis root-meristem size by controlling cell differentiation.   DOI:  10.1016/j.cub.2007.02.047 ;  PMID:  17363254
• MERISTEM-DEFECTIVE, an RS domain protein, is required for the correct meristem patterning and function in Arabidopsis.   DOI:  10.1111/j.1365-313X.2008.03738.x ;  PMID:  19000164
• Pluripotency of Arabidopsis xylem pericycle underlies shoot regeneration from root and hypocotyl explants grown in vitro.   DOI:  10.1111/j.1365-313X.2008.03715.x ;  PMID:  18980654
• Transcriptional networks in root cell fate specification.   DOI:  10.1016/j.bbagrm.2008.09.006 ;  PMID:  18973837
• PLETHORA proteins as dose-dependent master regulators of Arabidopsis root development.   DOI:  10.1038/nature06206 ;  PMID:  17960244
• What's the physiological role of domain II-less Aux/IAA proteins?   DOI:  10.4161/psb.3.7.5994 ;  PMID:  19704497
• SUMO E3 ligase HIGH PLOIDY2 regulates endocycle onset and meristem maintenance in Arabidopsis.   DOI:  10.1105/tpc.109.068072 ;  PMID:  19666737
• Control of Arabidopsis apical-basal embryo polarity by antagonistic transcription factors.   DOI:  10.1038/nature08843 ;  PMID:  20190735
• Auxin regulates distal stem cell differentiation in Arabidopsis roots.   DOI:  10.1073/pnas.1000672107 ;  PMID:  20543136
• Arabidopsis Tyrosylprotein sulfotransferase acts in the auxin/PLETHORA pathway in regulating postembryonic maintenance of the root stem cell niche.   DOI:  10.1105/tpc.110.075721 ;  PMID:  21045165
• RopGEF7 regulates PLETHORA-dependent maintenance of the root stem cell niche in Arabidopsis.   DOI:  10.1105/tpc.111.085514 ;  PMID:  21828289
• The basic helix-loop-helix transcription factor MYC2 directly represses PLETHORA expression during jasmonate-mediated modulation of the root stem cell niche in Arabidopsis.   DOI:  10.1105/tpc.111.089870 ;  PMID:  21954460
• SPT6L encoding a putative WG/GW-repeat protein regulates apical-basal polarity of embryo in Arabidopsis.   DOI:  10.1093/mp/ssr073 ;  PMID:  21948524
• LBD29 regulates the cell cycle progression in response to auxin during lateral root formation in Arabidopsis thaliana.   DOI:  10.1093/aob/mcs019 ;  PMID:  22334497
• A PLETHORA-auxin transcription module controls cell division plane rotation through MAP65 and CLASP.   DOI:  10.1016/j.cell.2012.02.051 ;  PMID:  22500804
• Stable establishment of cotyledon identity during embryogenesis in Arabidopsis by ANGUSTIFOLIA3 and HANABA TARANU.   DOI:  10.1242/dev.081547 ;  PMID:  22669825
• A genome-wide transcriptome profiling reveals the early molecular events during callus initiation in Arabidopsis multiple organs.   DOI:  10.1016/j.ygeno.2012.05.013 ;  PMID:  22664253
• Control of root meristem size by DA1-RELATED PROTEIN2 in Arabidopsis.   DOI:  10.1104/pp.112.210237 ;  PMID:  23296689
• Identification of SHRUBBY, a SHORT-ROOT and SCARECROW interacting protein that controls root growth and radial patterning.   DOI:  10.1242/dev.090761 ;  PMID:  23444357
• DAR2 acts as an important node connecting cytokinin, auxin, SHY2 and PLT1/2 in root meristem size control.   DOI:  10.4161/psb.24226 ;  PMID:  23518585
• The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants.   DOI:  10.4161/psb.20282 ;  PMID:  22580686
• TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis.   DOI:  10.1093/jxb/ert374 ;  PMID:  24277277
• The key players of the primary root growth and development also function in lateral roots in Arabidopsis.   DOI:  10.1007/s00299-014-1575-x ;  PMID:  24504658
• Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche.   DOI:  10.1111/jipb.12217 ;  PMID:  24831283
• ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis.   DOI:  10.1105/tpc.114.127902 ;  PMID:  25217509
• An Arabidopsis gene regulatory network for secondary cell wall synthesis.   DOI:  10.1038/nature14099 ;  PMID:  25533953
• ABA-mediated ROS in mitochondria regulate root meristem activity by controlling PLETHORA expression in Arabidopsis.   DOI:  10.1371/journal.pgen.1004791 ;  PMID:  25522358
• PLETHORA Genes Control Regeneration by a Two-Step Mechanism.   DOI:  10.1016/j.cub.2015.02.022 ;  PMID:  25819565
• Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis.   DOI:  10.1016/j.celrep.2015.04.013 ;  PMID:  25937286
• The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development.   DOI:  10.1093/jxb/erv230 ;  PMID:  25998905
• The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance.   DOI:  10.1105/tpc.15.00091 ;  PMID:  25991732
• A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis.   DOI:  10.1111/tpj.12911 ;  PMID:  26072661
• Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis.   DOI:  10.1073/pnas.1522639113 ;  PMID:  27001831
• RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana.   DOI:  10.1038/cr.2016.63 ;  PMID:  27229312
• The MADS-box XAANTAL1 increases proliferation at the Arabidopsis root stem-cell niche and participates in transition to differentiation by regulating cell-cycle components.   DOI:  10.1093/aob/mcw126 ;  PMID:  27474508
• The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.   DOI:  10.1105/tpc.16.00656 ;  PMID:  27920338
• ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis .   DOI:  10.1111/jipb.12506 ;  PMID:  28074634
• PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.   DOI:  10.1073/pnas.1714410114 ;  PMID:  29078398
• Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.   DOI:  10.1104/pp.17.00980 ;  PMID:  29233938
• GIF Transcriptional Coregulators Control Root Meristem Homeostasis.   DOI:  10.1105/tpc.17.00856 ;  PMID:  29352064
• Control of auxin-induced callus formation by bZIP59-LBD complex in Arabidopsis regeneration.   DOI:  10.1038/s41477-017-0095-4 ;  PMID:  29358751
• Histone chaperones play crucial roles in maintenance of stem cell niche during plant root development.   DOI:  10.1111/tpj.13933 ;  PMID:  29676825
• Epigenetic reprogramming by histone acetyltransferase HAG1/AtGCN5 is required for pluripotency acquisition in Arabidopsis.   DOI:  10.15252/embj.201798726 ;  PMID:  30061313
• Elongator Is Required for Root Stem Cell Maintenance by Regulating SHORTROOT Transcription.   DOI:  10.1104/pp.18.00534 ;  PMID:  30401723
• Cystathionine beta-lyase is crucial for embryo patterning and the maintenance of root stem cell niche in Arabidopsis.   DOI:  10.1111/tpj.14343 ;  PMID:  31002461
• The miR396-GRF Regulatory Module Controls the Embryogenic Response in Arabidopsis via an Auxin-Related Pathway.   DOI:  10.3390/ijms20205221 ;  PMID:  31640280
• AtMOB1 Genes Regulate Jasmonate Accumulation and Plant Development.   DOI:  10.1104/pp.19.01434 ;  PMID:  31862839
• RIBOSE PHOSPHATE ISOMERSASE 1 Influences Root Development by Acting on Cell Wall Biosynthesis, Actin Organization, and Auxin Transport in Arabidopsis.   DOI:  10.3389/fpls.2019.01641 ;  PMID:  31969892
• Arabidopsis thaliana trehalose-6-phosphate phosphatase gene TPPI enhances drought tolerance by regulating stomatal apertures.   DOI:  10.1093/jxb/eraa173 ;  PMID:  32242234
• Phosphoethanolamine N-methyltransferase 1 contributes to maintenance of root apical meristem by affecting ROS and auxin-regulated cell differentiation in Arabidopsis.   DOI:  10.1111/nph.16028 ;  PMID:  31246280
• The pre-mRNA splicing factor RDM16 regulates root stem cell maintenance in Arabidopsis.   DOI:  10.1111/jipb.13006 ;  PMID:  32790237
• The YDA-MKK4/MKK5-MPK3/MPK6 Cascade Functions Downstream of the RGF1-RGI Ligand-Receptor Pair in Regulating Mitotic Activity in Root Apical Meristem.   DOI:  10.1016/j.molp.2020.09.004 ;  PMID:  32916336
• RGF1-RGI1, a Peptide-Receptor Complex, Regulates Arabidopsis Root Meristem Development via a MAPK Signaling Cascade.   DOI:  10.1016/j.molp.2020.09.005 ;  PMID:  32916335
• Transcriptional Regulation of PLETHORA1 in the Root Meristem Through an Importin and Its Two Antagonistic Cargos.   DOI:  10.1105/tpc.20.00108 ;  PMID:  32989172
• Salicylic acid promotes quiescent center cell division through ROS accumulation and down-regulation of PLT1, PLT2, and WOX5.   DOI:  10.1111/jipb.13020 ;  PMID:  33017089
• N,N-dimethyl-hexadecylamine modulates Arabidopsis root growth through modifying the balance between stem cell niche and jasmonic acid-dependent gene expression.   DOI:  10.1016/j.gep.2021.119201 ;  PMID:  34329770
• Essential roles of SERKs in the ROOT MERISTEM GROWTH FACTOR-mediated signaling pathway.   DOI:  10.1093/plphys/kiac036 ;  PMID:  35134233
• SYNTAXIN OF PLANTS81 regulates root meristem activity and stem cell niche maintenance via ROS signaling.   DOI:  10.1093/plphys/kiac530 ;  PMID:  36427205
• A role for brassinosteroid signalling in decision-making processes in the Arabidopsis seedling.   DOI:  10.1371/journal.pgen.1010541 ;  PMID:  36508461
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.   DOI:  10.1093/molbev/msj051 ;  PMID:  16280546

Sequences: