Gene Details:
- Gene ID: AT3G20410
- Gene Symbol: CPK9
- Gene Name: calmodulin-domain protein kinase 9
- Description: calmodulin-domain protein kinase 9;(source:Araport11)
- TAIR Accession: locus:2092399
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Gene Ontology:
- GO:0005886 — located in — plasma membrane
- GO:0018105 — involved in — peptidyl-serine phosphorylation
- GO:0005737 — is active in — cytoplasm
- GO:0046777 — involved in — protein autophosphorylation
- GO:0005509 — enables — calcium ion binding
- GO:0009931 — enables — calcium-dependent protein serine/threonine kinase activity
- GO:0004683 — enables — calmodulin-dependent protein kinase activity
- GO:0006468 — has protein modification of type — protein phosphorylation
- GO:0007165 — acts upstream of or within — signal transduction
- GO:0035556 — involved in — intracellular signal transduction
- GO:0005516 — enables — calmodulin binding
- GO:0005829 — located in — cytosol
- GO:0005634 — is active in — nucleus
Literature:
- Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family. DOI: 10.1104/pp.005645 ; PMID: 12068094
- Analysis of EF-hand-containing proteins in Arabidopsis. DOI: 10.1186/gb-2002-3-10-research0056 ; PMID: 12372144
- The Arabidopsis CDPK-SnRK superfamily of protein kinases. DOI: 10.1104/pp.102.011999 ; PMID: 12805596
- Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. DOI: 10.1074/jbc.M307321200 ; PMID: 12912986
- Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. DOI: 10.1074/jbc.M308435200 ; PMID: 14576160
- Calcium/calmodulin-mediated signal network in plants. DOI: 10.1016/j.tplants.2003.09.004 ; PMID: 14557048
- Salt cress. A halophyte and cryophyte Arabidopsis relative model system and its applicability to molecular genetic analyses of growth and development of extremophiles. DOI: 10.1104/pp.104.041723 ; PMID: 15247369
- Salinity stress adaptation competence in the extremophile Thellungiella halophila in comparison with its relative Arabidopsis thaliana. DOI: 10.1111/j.1365-313X.2005.02587.x ; PMID: 16297073
- A quantitative analysis of Arabidopsis plasma membrane using trypsin-catalyzed (18)O labeling. DOI: 10.1074/mcp.M500414-MCP200 ; PMID: 16635983
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling. DOI: 10.4161/cc.7.23.7176 ; PMID: 19029837
- Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. DOI: 10.1016/j.phytochem.2011.02.029 ; PMID: 21477822
- Characterization of Arabidopsis calcium-dependent protein kinases: activated or not by calcium? DOI: 10.1042/BJ20112072 ; PMID: 22827269
- Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement. DOI: 10.3389/fchem.2017.00115 ; PMID: 29312925
- The Arabidopsis Calcium-Dependent Protein Kinases (CDPKs) and Their Roles in Plant Growth Regulation and Abiotic Stress Responses. DOI: 10.3390/ijms19071900 ; PMID: 29958430
- Calcium-dependent protein kinase CPK9 negatively functions in stomatal abscisic acid signaling by regulating ion channel activity in Arabidopsis. DOI: 10.1007/s11103-018-0805-y ; PMID: 30536042
- Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. DOI: 10.1074/jbc.M307321200 ; PMID: 12912986
- Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. DOI: 10.1074/mcp.T300006-MCP200 ; PMID: 14506206
- Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. DOI: 10.1093/molbev/msj051 ; PMID: 16280546
- Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. DOI: 10.1074/mcp.M600429-MCP200 ; PMID: 17317660
- MASCP Gator: an aggregation portal for the visualization of Arabidopsis proteomics data. DOI: 10.1104/pp.110.168195 ; PMID: 21075962
- Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement. DOI: 10.3389/fchem.2017.00115 ; PMID: 29312925
Sequences:
cDNA Sequence
- >AT3G20410.1
CAAAAGTCCCAAATCAAAACATCAATTTTCTTGTTCTTGTCAGCTACTCAAACCTCAACATGTTACATATATTTTTTCAGATAAAACAAATCATTCTCATCGTTCTTATCTGACCAGGAATAATTCAATGGAAGTATGAGTTTGACTCGGTTTCCTTTTGATATTAGTCGTACTTTTCAACATTTTACCTAGATAGAGCCGTCCTCTTATAATTATTCATCATTTCATGCTTCTCATGTTACATTTCTGCAATTTTTCAACTCTTTGATTTTATATAATCATTTGTTTCCTTTCTTAATCAAATCCATCTGGCTAACATTATTTAGCTTGATGCAATTAAGGTATATTATCTAATGAGGTGATGCTTCCACGTCTTTATATTATTATAATCCCTCAACAATTTTAAAAAAAGATCCTGACTTTCAATTTTCTCTCTTGTTTCTTCTTTTGATCATCTTCAACAAAAAAAAGTTACGATCTTTCTCTCCGGGTCATCGGAATTTGAGCTAGCTTAGCTAAAGTTCCGATCTTTCCTCTCTGGGTCGTCGGAATTTGAGCTTTTTAAAATCATGGGAAATTGTTTTGCCAAGAACCATGGATTGATGAAGCCACAGCAAAATGGTAATACCACTAGATCAGTTGAAGTAGGAGTAACCAACCAAGATCCACCGTCGTATACTCCACAAGCGAGAACCACTCAGCAGCCGGAGAAACCAGGTTCCGTGAATAGTCAACCACCACCGTGGAGGGCGGCGGCTGCAGCACCAGGACTAAGTCCCAAGACCACCACTAAGAGCAATTCAATACTAGAGAACGCTTTCGAAGACGTGAAGCTCTTTTACACATTGGGTAAAGAGCTAGGTCGTGGTCAATTTGGGGTAACGTATCTGTGCACAGAGAATTCCACGGGGAAGAAGTACGCTTGCAAATCGATCTCGAAGAAGAAGCTGGTGACTAAAGCTGATAAGGATGATATGAGGAGAGAGATTCAGATAATGCAGCATTTGAGTGGGCAGCCTAATATTGTGGAGTTTAAAGGAGCTTATGAGGATGAGAAAGCTGTGAATTTGGTGATGGAGCTTTGTGCTGGTGGTGAATTGTTTGATAGAATCATTGCTAAGGGACATTACACTGAGAGAGCTGCTGCTTCTGTTTGTAGACAGATTGTGAATGTTGTCAAGATTTGTCATTTCATGGGTGTGTTGCATAGAGACTTGAAGCCTGAGAATTTCTTGCTCTCTAGCAAAGATGAGAAGGCTTTGATCAAGGCTACTGATTTCGGATTGTCTGTCTTTATTGAAGAGGGAAAAGTATATAGAGATATTGTTGGGAGTGCATACTATGTTGCTCCAGAAGTCTTACGTCGCAGATATGGGAAAGAAGTTGATATCTGGAGTGCTGGAATCATCTTATACATTCTACTCAGCGGTGTGCCCCCGTTTTGGGCTGAGACTGAGAAAGGAATATTTGATGCTATATTGGAAGGCCATATCGACTTTGAGAGCCAACCATGGCCGTCAATCTCCAGCAGTGCCAAAGATTTGGTACGTAGAATGTTGACTGCGGATCCAAAAAGGCGGATTTCTGCTGCTGATGTTCTTCAGCATCCATGGCTTAGAGAAGGTGGAGAAGCATCAGACAAGCCAATTGACAGTGCTGTTCTCTCAAGGATGAAACAATTTAGAGCAATGAATAAGCTAAAGAAACTTGCTTTAAAGGTCATAGCGGAGAATATTGACACGGAAGAAATCCAAGGATTGAAGGCAATGTTTGCTAACATAGACACTGACAACAGTGGCACAATCACTTATGAAGAACTGAAAGAAGGATTAGCCAAATTGGGATCTAAACTCACAGAGGCAGAAGTGAAACAGCTCATGGATGCTGCTGATGTTGATGGGAACGGGTCCATCGACTACATAGAGTTTATTACAGCAACAATGCATAGGCACAGGCTTGAAAGTAATGAGAATCTTTACAAAGCTTTCCAGCATTTTGACAAAGACAGCAGCGGATACATTACAATAGACGAACTGGAATCTGCATTGAAGGAATATGGAATGGGAGATGATGCAACAATCAAAGAGGTTTTGTCAGATGTCGACTCCGATAACGATGGTAGAATCAACTATGAAGAGTTCTGCGCAATGATGAGAAGTGGAAATCCACAACAACAACAACCTCGGCTGTTCTAGTGGACATTGTTGCTGGATTAAAAGTCTTTTTGTTTGTATCTAATCCAGAAAAATCAGGAGCTGAATTAATGTTTGTTCAGACAAAAACCACGTAAAGAGGAAGATACTCAAAACTCTGATTGCTTGTGTTTTGTATTTTGTTCTTCACTTCTTCTGTTTTGTCCTTTGTGTTCTGTACTCAGGCTGTTGTGATATGAGAGAAAGAGAGGTTTCATTTTTACCGTTAAGATTTTGATCCTGACTGTGTTAACATTTTACCTCAGTTCCTCCACTTTTAATGTGATTCTCCATTCCATCAAATGTCAAATCAACGAAACAAC - >AT3G20410.2
CAAAAGTCCCAAATCAAAACATCAATTTTCTTGTTCTTGTCAGCTACTCAAACCTCAACATGTTACATATATTTTTTCAGATAAAACAAATCATTCTCATCGTTCTTATCTGACCAGGAATAATTCAATGGAAGTATGAGTTTGACTCGGTTTCCTTTTGATATTAGTCGTACTTTTCAACATTTTACCTAGATAGAGCCGTCCTCTTATAATTATTCATCATTTCATGCTTCTCATGTTACATTTCTGCAATTTTTCAACTCTTTGATTTTATATAATCATTTGTTTCCTTTCTTAATCAAATCCATCTGGCTAACATTATTTAGCTTGATGCAATTAAGGTATATTATCTAATGAGGTGATGCTTCCACGTCTTTATATTATTATAATCCCTCAACAATTTTAAAAAAAGATCCTGACTTTCAATTTTCTCTCTTGTTTCTTCTTTTGATCATCTTCAACAAAAAAAAGTTACGATCTTTCTCTCCGGGTCATCGGAATTTGAGCTAGCTTAGCTAAAGTTCCGATCTTTCCTCTCTGGGTCGTCGGAATTTGAGCTTTTTAAAATCATGGGAAATTGTTTTGCCAAGAACCATGGATTGATGAAGCCACAGCAAAATGGTAATACCACTAGATCAGTTGAAGTAGGAGTAACCAACCAAGATCCACCGTCGTATACTCCACAAGCGAGAACCACTCAGCAGCCGGAGAAACCAGGTTCCGTGAATAGTCAACCACCACCGTGGAGGGCGGCGGCTGCAGCACCAGGACTAAGTCCCAAGACCACCACTAAGAGCAATTCAATACTAGAGAACGCTTTCGAAGACGTGAAGCTCTTTTACACATTGGGTAAAGAGCTAGGTCGTGGTCAATTTGGGGTAACGTATCTGTGCACAGAGAATTCCACGGGGAAGAAGTACGCTTGCAAATCGATCTCGAAGAAGAAGCTGGTGACTAAAGCTGATAAGGATGATATGAGGAGAGAGATTCAGATAATGCAGCATTTGAGTGGGCAGCCTAATATTGTGGAGTTTAAAGGAGCTTATGAGGATGAGAAAGCTGTGAATTTGGTGATGGAGCTTTGTGCTGGTGGTGAATTGTTTGATAGAATCATTGCTAAGGGACATTACACTGAGAGAGCTGCTGCTTCTGTTTGTAGACAGATTGTGAATGTTGTCAAGATTTGTCATTTCATGGGTGTGTTGCATAGAGACTTGAAGCCTGAGAATTTCTTGCTCTCTAGCAAAGATGAGAAGGCTTTGATCAAGGCTACTGATTTCGGATTGTCTGTCTTTATTGAAGAGGGAAAAGTATATAGAGATATTGTTGGGAGTGCATACTATGTTGCTCCAGAAGTCTTACGTCGCAGATATGGGAAAGAAGTTGATATCTGGAGTGCTGGAATCATCTTATACATTCTACTCAGCGGTGTGCCCCCGTTTTGGGCTGAGACTGAGAAAGGAATATTTGATGCTATATTGGAAGGCCATATCGACTTTGAGAGCCAACCATGGCCGTCAATCTCCAGCAGTGCCAAAGATTTGGTACGTAGAATGTTGACTGCGGATCCAAAAAGGCGGATTTCTGCTGCTGATGTTCTTCAGCATCCATGGCTTAGAGAAGGTGGAGAAGCATCAGACAAGCCAATTGACAGTGCTGTTCTCTCAAGGATGAAACAATTTAGAGCAATGAATAAGCTAAAGAAACTTGCTTTAAAGGTCATAGCGGAGAATATTGACACGGAAGAAATCCAAGGATTGAAGGCAATGTTTGCTAACATAGACACTGACAACAGTGGCACAATCACTTATGAAGAACTGAAAGAAGGATTAGCCAAATTGGGATCTAAACTCACAGAGGCAGAAGTGAAACAGCTCATGGATGCTGCTGATGTTGATGGGAACGGGTCCATCGACTACATAGAGTTTATTACAGCAACAATGCATAGGCACAGGCTTGAAAGTAATGAGAATCTTTACAAAGCTTTCCAGCATTTTGACAAAGACAGCAGCGGATACATTACAATAGACGAACTGGAATCTGCATTGAAGGAATATGGAATGGGAGATGATGCAACAATCAAAGAGGTTTTGTCAGATGTCGACTCCGATAACGATGGTAGAATCAACTATGAAGAGTTCTGCGCAATGATGAGAAGTGGAAATCCACAACAACAACAACCTCGGCTGTTCTAGTGGACATTGTTGCTGGATTAAAAGTCTTTTTGTTTGTATCTAATCCAGAAAAATCAGGAGCTGAATTAATGTTTGTTCAGACAAAAACCACGTAAAGAGGAAGATACTCAAAACTCTGATTGCTTGTGTTTTGTATTTTGTTCTTCACTTCTTCTGTTTTGTCCTTTGTGTTCTGTACTCAGGCTGTTGTGATATGAGAGAAAGAGAGGTTTCATTTTTACCGTTAAGATTTTGATCCTGACTGTGTTAACATTTTACCTCAGTTCCTCCACTTTTAATGTGATTCTCCATTCCATCAAATGTCAAATCAACGAAACAAC
CDS Sequence
- >AT3G20410.1
ATGGGAAATTGTTTTGCCAAGAACCATGGATTGATGAAGCCACAGCAAAATGGTAATACCACTAGATCAGTTGAAGTAGGAGTAACCAACCAAGATCCACCGTCGTATACTCCACAAGCGAGAACCACTCAGCAGCCGGAGAAACCAGGTTCCGTGAATAGTCAACCACCACCGTGGAGGGCGGCGGCTGCAGCACCAGGACTAAGTCCCAAGACCACCACTAAGAGCAATTCAATACTAGAGAACGCTTTCGAAGACGTGAAGCTCTTTTACACATTGGGTAAAGAGCTAGGTCGTGGTCAATTTGGGGTAACGTATCTGTGCACAGAGAATTCCACGGGGAAGAAGTACGCTTGCAAATCGATCTCGAAGAAGAAGCTGGTGACTAAAGCTGATAAGGATGATATGAGGAGAGAGATTCAGATAATGCAGCATTTGAGTGGGCAGCCTAATATTGTGGAGTTTAAAGGAGCTTATGAGGATGAGAAAGCTGTGAATTTGGTGATGGAGCTTTGTGCTGGTGGTGAATTGTTTGATAGAATCATTGCTAAGGGACATTACACTGAGAGAGCTGCTGCTTCTGTTTGTAGACAGATTGTGAATGTTGTCAAGATTTGTCATTTCATGGGTGTGTTGCATAGAGACTTGAAGCCTGAGAATTTCTTGCTCTCTAGCAAAGATGAGAAGGCTTTGATCAAGGCTACTGATTTCGGATTGTCTGTCTTTATTGAAGAGGGAAAAGTATATAGAGATATTGTTGGGAGTGCATACTATGTTGCTCCAGAAGTCTTACGTCGCAGATATGGGAAAGAAGTTGATATCTGGAGTGCTGGAATCATCTTATACATTCTACTCAGCGGTGTGCCCCCGTTTTGGGCTGAGACTGAGAAAGGAATATTTGATGCTATATTGGAAGGCCATATCGACTTTGAGAGCCAACCATGGCCGTCAATCTCCAGCAGTGCCAAAGATTTGGTACGTAGAATGTTGACTGCGGATCCAAAAAGGCGGATTTCTGCTGCTGATGTTCTTCAGCATCCATGGCTTAGAGAAGGTGGAGAAGCATCAGACAAGCCAATTGACAGTGCTGTTCTCTCAAGGATGAAACAATTTAGAGCAATGAATAAGCTAAAGAAACTTGCTTTAAAGGTCATAGCGGAGAATATTGACACGGAAGAAATCCAAGGATTGAAGGCAATGTTTGCTAACATAGACACTGACAACAGTGGCACAATCACTTATGAAGAACTGAAAGAAGGATTAGCCAAATTGGGATCTAAACTCACAGAGGCAGAAGTGAAACAGCTCATGGATGCTGCTGATGTTGATGGGAACGGGTCCATCGACTACATAGAGTTTATTACAGCAACAATGCATAGGCACAGGCTTGAAAGTAATGAGAATCTTTACAAAGCTTTCCAGCATTTTGACAAAGACAGCAGCGGATACATTACAATAGACGAACTGGAATCTGCATTGAAGGAATATGGAATGGGAGATGATGCAACAATCAAAGAGGTTTTGTCAGATGTCGACTCCGATAACGATGGTAGAATCAACTATGAAGAGTTCTGCGCAATGATGAGAAGTGGAAATCCACAACAACAACAACCTCGGCTGTTCTAG - >AT3G20410.2
ATGGGAAATTGTTTTGCCAAGAACCATGGATTGATGAAGCCACAGCAAAATGGTAATACCACTAGATCAGTTGAAGTAGGAGTAACCAACCAAGATCCACCGTCGTATACTCCACAAGCGAGAACCACTCAGCAGCCGGAGAAACCAGGTTCCGTGAATAGTCAACCACCACCGTGGAGGGCGGCGGCTGCAGCACCAGGACTAAGTCCCAAGACCACCACTAAGAGCAATTCAATACTAGAGAACGCTTTCGAAGACGTGAAGCTCTTTTACACATTGGGTAAAGAGCTAGGTCGTGGTCAATTTGGGGTAACGTATCTGTGCACAGAGAATTCCACGGGGAAGAAGTACGCTTGCAAATCGATCTCGAAGAAGAAGCTGGTGACTAAAGCTGATAAGGATGATATGAGGAGAGAGATTCAGATAATGCAGCATTTGAGTGGGCAGCCTAATATTGTGGAGTTTAAAGGAGCTTATGAGGATGAGAAAGCTGTGAATTTGGTGATGGAGCTTTGTGCTGGTGGTGAATTGTTTGATAGAATCATTGCTAAGGGACATTACACTGAGAGAGCTGCTGCTTCTGTTTGTAGACAGATTGTGAATGTTGTCAAGATTTGTCATTTCATGGGTGTGTTGCATAGAGACTTGAAGCCTGAGAATTTCTTGCTCTCTAGCAAAGATGAGAAGGCTTTGATCAAGGCTACTGATTTCGGATTGTCTGTCTTTATTGAAGAGGGAAAAGTATATAGAGATATTGTTGGGAGTGCATACTATGTTGCTCCAGAAGTCTTACGTCGCAGATATGGGAAAGAAGTTGATATCTGGAGTGCTGGAATCATCTTATACATTCTACTCAGCGGTGTGCCCCCGTTTTGGGCTGAGACTGAGAAAGGAATATTTGATGCTATATTGGAAGGCCATATCGACTTTGAGAGCCAACCATGGCCGTCAATCTCCAGCAGTGCCAAAGATTTGGTACGTAGAATGTTGACTGCGGATCCAAAAAGGCGGATTTCTGCTGCTGATGTTCTTCAGCATCCATGGCTTAGAGAAGGTGGAGAAGCATCAGACAAGCCAATTGACAGTGCTGTTCTCTCAAGGATGAAACAATTTAGAGCAATGAATAAGCTAAAGAAACTTGCTTTAAAGGTCATAGCGGAGAATATTGACACGGAAGAAATCCAAGGATTGAAGGCAATGTTTGCTAACATAGACACTGACAACAGTGGCACAATCACTTATGAAGAACTGAAAGAAGGATTAGCCAAATTGGGATCTAAACTCACAGAGGCAGAAGTGAAACAGCTCATGGATGCTGCTGATGTTGATGGGAACGGGTCCATCGACTACATAGAGTTTATTACAGCAACAATGCATAGGCACAGGCTTGAAAGTAATGAGAATCTTTACAAAGCTTTCCAGCATTTTGACAAAGACAGCAGCGGATACATTACAATAGACGAACTGGAATCTGCATTGAAGGAATATGGAATGGGAGATGATGCAACAATCAAAGAGGTTTTGTCAGATGTCGACTCCGATAACGATGGTAGAATCAACTATGAAGAGTTCTGCGCAATGATGAGAAGTGGAAATCCACAACAACAACAACCTCGGCTGTTCTAG
Protein Sequence
- >AT3G20410.1
MGNCFAKNHGLMKPQQNGNTTRSVEVGVTNQDPPSYTPQARTTQQPEKPGSVNSQPPPWRAAAAAPGLSPKTTTKSNSILENAFEDVKLFYTLGKELGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLRRRYGKEVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDLVRRMLTADPKRRISAADVLQHPWLREGGEASDKPIDSAVLSRMKQFRAMNKLKKLALKVIAENIDTEEIQGLKAMFANIDTDNSGTITYEELKEGLAKLGSKLTEAEVKQLMDAADVDGNGSIDYIEFITATMHRHRLESNENLYKAFQHFDKDSSGYITIDELESALKEYGMGDDATIKEVLSDVDSDNDGRINYEEFCAMMRSGNPQQQQPRLF - >AT3G20410.2
MGNCFAKNHGLMKPQQNGNTTRSVEVGVTNQDPPSYTPQARTTQQPEKPGSVNSQPPPWRAAAAAPGLSPKTTTKSNSILENAFEDVKLFYTLGKELGRGQFGVTYLCTENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLRRRYGKEVDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDLVRRMLTADPKRRISAADVLQHPWLREGGEASDKPIDSAVLSRMKQFRAMNKLKKLALKVIAENIDTEEIQGLKAMFANIDTDNSGTITYEELKEGLAKLGSKLTEAEVKQLMDAADVDGNGSIDYIEFITATMHRHRLESNENLYKAFQHFDKDSSGYITIDELESALKEYGMGDDATIKEVLSDVDSDNDGRINYEEFCAMMRSGNPQQQQPRLF