Gene Details:

• Gene ID: AT3G19820
• Gene Symbol: CBB1, DIM, DIM1, DWF1, EVE1
• Gene Name: CABBAGE 1, DIMINUTIA, DIMINUTO 1, DWARF 1, ENHANCED VERY-LOW-FLUENCE RESPONSES 1
• Description: cell elongation protein / DWARF1 / DIMINUTO (DIM);(source:Araport11)
• TAIR Accession: locus:2092276
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G19820.1     AT3G19820.2     AT3G19820.3

Gene Ontology:

• GO:0016628  — enables — oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
• GO:0009808  — acts upstream of or within — lignin metabolic process
• GO:0005737  — is active in — cytoplasm
• GO:0016132  — acts upstream of or within — brassinosteroid biosynthetic process
• GO:0009826  — acts upstream of or within — unidimensional cell growth
• GO:0000325  — located in — plant-type vacuole
• GO:0006694  — acts upstream of or within — steroid biosynthetic process
• GO:0005634  — located in — nucleus
• GO:0005773  — located in — vacuole
• GO:0008202  — involved in — steroid metabolic process
• GO:0009834  — acts upstream of or within — plant-type secondary cell wall biogenesis
• GO:0071949  — enables — FAD binding
• GO:0003824  — enables — catalytic activity
• GO:0005515  — enables — protein binding
• GO:0005516  — enables — calmodulin binding
• GO:0009416  — acts upstream of or within — response to light stimulus
• GO:0005829  — located in — cytosol
• GO:0050614  — enables — delta24-sterol reductase activity

Germplasm Phenotype:

• CS291  — dwarf due to reduced cell expansion; reduced leaf expansion and stunted inflorescence; reduced hypocotyl elongation; opened coyledons after germination in darkness.
• CS8100  — reduced plant height; short roots, hypocotyls, petioles and stems; reduced cell length along longitudinal axes of these organs; round, curly, dark-green leaves; similar to de-etiolated mutants (det); increased effect of light on hypocotyl length; when grown in the dark, dim seedlings have short hypocotyls, no apical hooks, open cotyledons, primary leaf buds, and normal etioplasts; affects expression of a beta-tubulin gene (TUB1); slightly delayed flowering; reduced fertility

Literature:

• The Arabidopsis dwarf1 mutant is defective in the conversion of 24-methylenecholesterol to campesterol in brassinosteroid biosynthesis.   DOI:  10.1104/pp.119.3.897 ;  PMID:  10069828
• The DIMINUTO gene of Arabidopsis is involved in regulating cell elongation.   DOI:  10.1101/gad.9.1.97 ;  PMID:  7828854
• Brassinosteroid mutants uncover fine tuning of phytochrome signaling.   DOI:  7029 ;  PMID:  11788763
• Brassinosteroids control the proliferation of leaf cells of Arabidopsis thaliana.   DOI:  10.1093/pcp/pcf024 ;  PMID:  11867704
• Brassinosteroid-regulated gene expression.   DOI:  10.1104/pp.011003 ;  PMID:  12114578
• Interactions between sterol biosynthesis genes in embryonic development of Arabidopsis.   DOI:  10.1046/j.1365-313x.2002.01333.x ;  PMID:  12100483
• Brassinosteroids promote root growth in Arabidopsis.   DOI:  10.1104/pp.103.028662 ;  PMID:  14526105
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Transcript profiling of cytokinin action in Arabidopsis roots and shoots discovers largely similar but also organ-specific responses.   DOI:  10.1186/1471-2229-12-112 ;  PMID:  22824128
• Phototropin 1 and cryptochrome action in response to green light in combination with other wavelengths.   DOI:  10.1007/s00425-012-1767-y ;  PMID:  23007554
• Function and molecular regulation of DWARF1 as a C-24 reductase in brassinosteroid biosynthesis in Arabidopsis.   DOI:  10.1093/jxb/ery038 ;  PMID:  29432595
• The DIMINUTO gene of Arabidopsis is involved in regulating cell elongation.   DOI:  10.1101/gad.9.1.97 ;  PMID:  7828854
• Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.   DOI:  10.1093/pcp/pch099 ;  PMID:  15215502
• The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins.   DOI:  10.1105/tpc.104.027078 ;  PMID:  15539469
• A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.   DOI:  10.1074/mcp.M600250-MCP200 ;  PMID:  17151019
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.   DOI:  10.1093/pcp/pch099 ;  PMID:  15215502
• The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins.   DOI:  10.1105/tpc.104.027078 ;  PMID:  15539469
• A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.   DOI:  10.1074/mcp.M600250-MCP200 ;  PMID:  17151019
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890

Sequences: