Gene Details:

• Gene ID: AT3G19480
• Gene Symbol: 3-PGDH, PGDH3
• Gene Name: phosphoglycerate dehydrogenase 3
• Description: D-3-phosphoglycerate dehydrogenase;(source:Araport11)
• TAIR Accession: locus:2090649
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G19480.1

Gene Ontology:

• GO:0009570  — located in — chloroplast stroma
• GO:0004617  — enables — phosphoglycerate dehydrogenase activity
• GO:0009507  — located in — chloroplast
• GO:0006564  — involved in — L-serine biosynthetic process
• GO:0051287  — enables — NAD binding
• GO:0009570  — is active in — chloroplast stroma
• GO:0003954  — enables — NADH dehydrogenase activity
• GO:0005739  — located in — mitochondrion
• GO:0009643  — acts upstream of or within — photosynthetic acclimation

Germplasm Phenotype:

• CS72462  — elevated transient nonphotochemical quenching (NPQ) under nonsaturating light conditions, photosystem II damage under long-term fluctuating light stress; higher cellular ATP content; decreased chloroplast amino acid level
• CS72463  — elevated transient nonphotochemical quenching (NPQ) under nonsaturating light conditions, photosystem II damage under long-term fluctuating light stress; higher cellular ATP content
• CS72464  — elevated transient nonphotochemical quenching (NPQ) under nonsaturating light conditions, photosystem II damage and decreased biomass under long-term fluctuating light stress; reduced sodium tolerance
• SALK_008491  — Transient high NPQ in SALK_008491 is caused by loss of PGDH3.

Literature:

• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.   DOI:  10.1105/tpc.016055 ;  PMID:  14671022
• Genome-wide analysis of Arabidopsis responsive transcriptome to nitrogen limitation and its regulation by the ubiquitin ligase gene NLA.   DOI:  10.1007/s11103-007-9241-0 ;  PMID:  17885809
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Functional characterization of the plastidial 3-phosphoglycerate dehydrogenase family in Arabidopsis.   DOI:  10.1104/pp.113.226720 ;  PMID:  24058165
• Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis.   DOI:  10.1105/tpc.113.118992 ;  PMID:  24368794
• PGDH family genes differentially affect Arabidopsis tolerance to salt stress.   DOI:  10.1016/j.plantsci.2019.110284 ;  PMID:  31779918
• Phosphoglycerate dehydrogenase genes differentially affect Arabidopsis metabolism and development.   DOI:  10.1016/j.plantsci.2021.110863 ;  PMID:  33775368
• Regulation of serine biosynthesis in Arabidopsis. Crucial role of plastidic 3-phosphoglycerate dehydrogenase in non-photosynthetic tissues.   DOI:  10.1074/jbc.274.1.397 ;  PMID:  9867856
• Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.   DOI:  10.1105/tpc.016055 ;  PMID:  14671022
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequences: