Gene Details:
- Gene ID: AT3G19240
- Gene Symbol: DEM2
- Gene Name: DEFECTIVE EMBRYO AND MERISTEMS 2
- Description: Vacuolar import/degradation, Vid27-related protein;(source:Araport11)
- TAIR Accession: locus:2094113
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
- PO:0025195 — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
Gene Ontology:
- GO:0006355 — acts upstream of or within — regulation of DNA-templated transcription
- GO:0005515 — enables — protein binding
- GO:0005635 — located in — nuclear envelope
- GO:0005737 — located in — cytoplasm
- GO:0005737 — is active in — cytoplasm
- GO:0097305 — acts upstream of or within — response to alcohol
- GO:0006499 — has protein modification of type — N-terminal protein myristoylation
- GO:0033993 — acts upstream of or within — response to lipid
- GO:0033036 — acts upstream of or within — macromolecule localization
- GO:0005634 — is active in — nucleus
Germplasm Phenotype:
- DEM1/dem1 dem2/dem2 — During male reproductive development, chromosomes fail to align on the metaphase plate at meiosis II and result in abnormal numbers of daughter cells following meiosis. Plants show defects in both pollen and embryo sac development, and produce defective male and female gametes
Function-related keywords:
Literature:
- Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. DOI: 10.1074/jbc.M307321200 ; PMID: 12912986
- Transcript profiling in Arabidopsis reveals complex responses to global inhibition of DNA methylation and histone deacetylation. DOI: 10.1074/jbc.M409053200 ; PMID: 15516340
- N-myristoylation regulates the SnRK1 pathway in Arabidopsis. DOI: 10.1105/tpc.107.051870 ; PMID: 17827350
- Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. DOI: 10.1104/pp.108.126375 ; PMID: 18775970
- Acyl-lipid metabolism. DOI: 10.1199/tab.0161 ; PMID: 23505340
- Endogenous Arabidopsis messenger RNAs transported to distant tissues. DOI: 10.1038/nplants.2015.25 ; PMID: 27247031
- Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote. DOI: 10.1074/jbc.M307321200 ; PMID: 12912986
Sequences:
cDNA Sequence
- >AT3G19240.1
GTTTTTTTTAGAACGACTCTGTCTGCAACAGAGTGACTCGGAGTGACCAACGCGTCCTAAAAGCGTTGCGTCATGTTGAAGCAAACCCAACTTTATTCCGACGCTAACCAACAGATTCACGAAACCCTATAAATACTTAGAAATCCCTAATCCTCCTCTAAATCCCTAACTTCTTCCCCTACACTCTCTCACACAATTTTCTCGAGAAATTTTCCAATTTCCTTTCGATTTCGCCCAGAAATTTCGGTAACTTTCAGATTCTGTTCAGAACGAAGAAACTTGTTATTTTTGGCTACTTCTCTCCGATTCTGTTCTTCTTGTAGTAGCTGATCGCATTCCATGGGTACTTCTCAGAGTCGTGAAGATCGAATCAGCGAATCGGATACAGAATCCGATTCAGATTACTATGAAGAAGAAGACGAGGATCAATACGATGACGCGAAGAAGCAAGGATCATCATCTGTTTCTGGTACAAGACCGTCTGATTCTTCTTCTTCTTCAGGACCAACTGATTCATCGTCTCTCGATATTGAGCAGAAGCTAAAAGCCTTGAAGTTGAAATACCCATCTTCTTCTTCCGTAACACCCAAGATGAAGAACGCTGTGAAGCTTTACCGCCATATCGGGGGAAACACACCCAAAGCGAAATGGATCGTTTCGGATAAGATGACATCATACAAGTTTGTGAAAACTTCGTCAGTGGATGGAGAAGATATTGATGATTATGATGATTGTGAAGAATCAGGTGAAGGAGGTGAGTCTTTTTGGTTTCTGGGTGTTGGTACTAAGGTTAAAGCTAGGGTTTCTACGGATATGCAGTTGAAAATGTTTGGGGATCAACGTAGGGTTGACTTTGTTAGTAATGGTGTTTGGGCTTTGAAGTTCTTGACGGATGAGGATTATAGGAAGTTTGTTACTAGGTTTCAGGACTATCTGTTTGAGAATGTGTATAAGATCAGGGCAAGTGAGGAGAATAGAGTTAAAGTGTATGGTAAAGATTTCATTGGGTGGGCTAATCCTGAGGCTGCTGATGATTCTATGTGGGAGGATGCTGAAGCTCCACCTGAGGAAGAGGAAACTCAGGGGAAGAGGAATACGGATTTGACGGAAGAGTTTGAAGAGGTGGCTAATGGTGGAGTGCAGAGTTTGACTTTGGGAGCGTTGGATAATTCGTTCTTGGTGAATGATTATGGGGTTCAGGTTTATAGGAATATGGAGCGTGGTATTCATGGGAAAGGTGTGTGCGTGAGATTTGATTCTGGAAACTCAAAGTTCGGATCAGGGTCAAGCCAGACAACACCGAACAAGGCTCTTTTGATGAGGGCAGAGACTAATATGATGCTGATGAGTCCAGCTAAACAAGGGAAACCTAACTCCACTGGTGTTAAGCAGCTCGATATAGAGTCAGGGAAGATTGTTACTGAATGGAAATTTGAGAAAGACGGGACTGAAATCACGATGAGAGACATAACAAATGATACCAAAGGGTCGCAGCTAGATCCATCAGAGTCAACGTTTTTGGGATTGGATGACAATAGGCTGTGTCAATGGGACATGAGGGATAGGAGAGGTATAGTGCAGAACATTGACTCTCCCATCTTGGAATGGACTCAAGGCCATCAGTTCTCTAGAGGAACAAATTTCCAGTGCTTTGCAACTACTGGAGATGGGTCAATCGTTGTGGGATCACTTGACGGAAAGATAAGACTTTACTCAAAGACCTCAATGAGAATGGCAAAAACGGCTTTTCCAGGGCTCGGTTCACCAATTACACATGTGGACGTTTCTTATGATGGGAAATGGATACTGGGCACCACAGATACGTACTTGGTTCTTATTTGCACCCTTTTCACAGACAAAAATGGTCTGACAAAAACAGGCTTTAGCGGAAGAATGGGAAACAAAATACCAGCCCCTAGGCTGCTGAAGCTAACACCACTAGATTCACACTTGGCAGGAAAAGATAATAAGTTTCATGGCGGTCACTTCTCATGGGTAACTGAGAGTGGAAAGCAAGAGAGACACATAGTAGCAACAGTGGGGAAATTCAGTGTGATATGGGACTTGGAGCGGGTGAAGAACAGTGCACACGAATGCTATAGGAACCAACAAGGACTCAAGAGCTGTTACTGCTACAAGATCTTGTTGAAGGATGAGTCAATTGTTGAGAGCCGATTCATGCACGATAACTTCTCCTTCTCCGGTAACAAATCGCCAGAAGCACCGCTTGTGGTTGCCACGCCTTTGAAAGTCAGCTCCATCAGCCTCTCTGGAAAACGACTTTAAATAACCAGTTTGTATCGTAAAGCTTTCTTTTGTTTTTGTAATGAAATTTGATTGTAGTGTTTGGCTTTTTGTCATCGTGTGAAGGTTTGTGAATGAGTGACATTTTGCTTTTTACTCAAATATGACTACTCAAATTCTCTTCATGACTTGATTTTATTCTTCAAATAGACACATTTTGTGAACAGCTAATGTTAAATCTTTAACCTGAAGTGAAAAAAACAAAATAATTGTCTGATTTGATGATATGAACCAATACAACATCCAATATCTGCTTAATGCAGACAAGTCTATGATCTATCAAATATGATGATAAAAAGTCTCTATTCCTAGCTACAGATACAACGTCTGTATATTGCCTCGGTCCTGTTGTCCTCTCGCATAAGCTCAAAAAACCACTGATACAAATAGGTTGAGGAGCTTACGTTTGGGGACGAAGGATCTCTTTAAGGAGCAACGATCTGGATTTGTTAACATTAGTGAACCAACGACATATATGATCCACAAGAACCTCGAGTTGATGGGTGTGGTTAACATGGCTCTTTCGAAGCTGTTTCACAAACTCCGGAATTGTATACACGTCCCTCCCCCTCTCTAATCC
CDS Sequence
- >AT3G19240.1
ATGGGTACTTCTCAGAGTCGTGAAGATCGAATCAGCGAATCGGATACAGAATCCGATTCAGATTACTATGAAGAAGAAGACGAGGATCAATACGATGACGCGAAGAAGCAAGGATCATCATCTGTTTCTGGTACAAGACCGTCTGATTCTTCTTCTTCTTCAGGACCAACTGATTCATCGTCTCTCGATATTGAGCAGAAGCTAAAAGCCTTGAAGTTGAAATACCCATCTTCTTCTTCCGTAACACCCAAGATGAAGAACGCTGTGAAGCTTTACCGCCATATCGGGGGAAACACACCCAAAGCGAAATGGATCGTTTCGGATAAGATGACATCATACAAGTTTGTGAAAACTTCGTCAGTGGATGGAGAAGATATTGATGATTATGATGATTGTGAAGAATCAGGTGAAGGAGGTGAGTCTTTTTGGTTTCTGGGTGTTGGTACTAAGGTTAAAGCTAGGGTTTCTACGGATATGCAGTTGAAAATGTTTGGGGATCAACGTAGGGTTGACTTTGTTAGTAATGGTGTTTGGGCTTTGAAGTTCTTGACGGATGAGGATTATAGGAAGTTTGTTACTAGGTTTCAGGACTATCTGTTTGAGAATGTGTATAAGATCAGGGCAAGTGAGGAGAATAGAGTTAAAGTGTATGGTAAAGATTTCATTGGGTGGGCTAATCCTGAGGCTGCTGATGATTCTATGTGGGAGGATGCTGAAGCTCCACCTGAGGAAGAGGAAACTCAGGGGAAGAGGAATACGGATTTGACGGAAGAGTTTGAAGAGGTGGCTAATGGTGGAGTGCAGAGTTTGACTTTGGGAGCGTTGGATAATTCGTTCTTGGTGAATGATTATGGGGTTCAGGTTTATAGGAATATGGAGCGTGGTATTCATGGGAAAGGTGTGTGCGTGAGATTTGATTCTGGAAACTCAAAGTTCGGATCAGGGTCAAGCCAGACAACACCGAACAAGGCTCTTTTGATGAGGGCAGAGACTAATATGATGCTGATGAGTCCAGCTAAACAAGGGAAACCTAACTCCACTGGTGTTAAGCAGCTCGATATAGAGTCAGGGAAGATTGTTACTGAATGGAAATTTGAGAAAGACGGGACTGAAATCACGATGAGAGACATAACAAATGATACCAAAGGGTCGCAGCTAGATCCATCAGAGTCAACGTTTTTGGGATTGGATGACAATAGGCTGTGTCAATGGGACATGAGGGATAGGAGAGGTATAGTGCAGAACATTGACTCTCCCATCTTGGAATGGACTCAAGGCCATCAGTTCTCTAGAGGAACAAATTTCCAGTGCTTTGCAACTACTGGAGATGGGTCAATCGTTGTGGGATCACTTGACGGAAAGATAAGACTTTACTCAAAGACCTCAATGAGAATGGCAAAAACGGCTTTTCCAGGGCTCGGTTCACCAATTACACATGTGGACGTTTCTTATGATGGGAAATGGATACTGGGCACCACAGATACGTACTTGGTTCTTATTTGCACCCTTTTCACAGACAAAAATGGTCTGACAAAAACAGGCTTTAGCGGAAGAATGGGAAACAAAATACCAGCCCCTAGGCTGCTGAAGCTAACACCACTAGATTCACACTTGGCAGGAAAAGATAATAAGTTTCATGGCGGTCACTTCTCATGGGTAACTGAGAGTGGAAAGCAAGAGAGACACATAGTAGCAACAGTGGGGAAATTCAGTGTGATATGGGACTTGGAGCGGGTGAAGAACAGTGCACACGAATGCTATAGGAACCAACAAGGACTCAAGAGCTGTTACTGCTACAAGATCTTGTTGAAGGATGAGTCAATTGTTGAGAGCCGATTCATGCACGATAACTTCTCCTTCTCCGGTAACAAATCGCCAGAAGCACCGCTTGTGGTTGCCACGCCTTTGAAAGTCAGCTCCATCAGCCTCTCTGGAAAACGACTTTAA
Protein Sequence
- >AT3G19240.1
MGTSQSREDRISESDTESDSDYYEEEDEDQYDDAKKQGSSSVSGTRPSDSSSSSGPTDSSSLDIEQKLKALKLKYPSSSSVTPKMKNAVKLYRHIGGNTPKAKWIVSDKMTSYKFVKTSSVDGEDIDDYDDCEESGEGGESFWFLGVGTKVKARVSTDMQLKMFGDQRRVDFVSNGVWALKFLTDEDYRKFVTRFQDYLFENVYKIRASEENRVKVYGKDFIGWANPEAADDSMWEDAEAPPEEEETQGKRNTDLTEEFEEVANGGVQSLTLGALDNSFLVNDYGVQVYRNMERGIHGKGVCVRFDSGNSKFGSGSSQTTPNKALLMRAETNMMLMSPAKQGKPNSTGVKQLDIESGKIVTEWKFEKDGTEITMRDITNDTKGSQLDPSESTFLGLDDNRLCQWDMRDRRGIVQNIDSPILEWTQGHQFSRGTNFQCFATTGDGSIVVGSLDGKIRLYSKTSMRMAKTAFPGLGSPITHVDVSYDGKWILGTTDTYLVLICTLFTDKNGLTKTGFSGRMGNKIPAPRLLKLTPLDSHLAGKDNKFHGGHFSWVTESGKQERHIVATVGKFSVIWDLERVKNSAHECYRNQQGLKSCYCYKILLKDESIVESRFMHDNFSFSGNKSPEAPLVVATPLKVSSISLSGKRL