Gene Details:

• Gene ID: AT3G19190
• Gene Symbol: ATATG2, ATG2, PEUP1
• Gene Name: AUTOPHAGY 2, PEROXISOME UNUSUAL POSITIONING 1
• Description: autophagy 2;(source:Araport11)
• TAIR Accession: locus:2094063
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G19190.1     AT3G19190.3     AT3G19190.2

Gene Ontology:

• GO:0061709  — involved in — reticulophagy
• GO:0050832  — involved in — defense response to fungus
• GO:0032266  — enables — phosphatidylinositol-3-phosphate binding
• GO:0000045  — involved in — autophagosome assembly
• GO:0000422  — involved in — autophagy of mitochondrion
• GO:0034727  — involved in — piecemeal microautophagy of the nucleus
• GO:0005634  — located in — nucleus
• GO:0010150  — involved in — leaf senescence
• GO:0010150  — acts upstream of or within — leaf senescence
• GO:0042742  — involved in — defense response to bacterium
• GO:0000407  — is active in — phagophore assembly site
• GO:0044805  — involved in — late nucleophagy

Germplasm Phenotype:

• SALK_076727  — early senescence; accumulation of high levels of reactive oxygen species.

Literature:

• Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis.   DOI:  10.1105/tpc.109.068635 ;  PMID:  19773385
• A revised assay for monitoring autophagic flux in Arabidopsis thaliana reveals involvement of AUTOPHAGY-RELATED9 in autophagy.   DOI:  10.14348/molcells.2014.0042 ;  PMID:  24805779
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis.   DOI:  10.1105/tpc.17.00056 ;  PMID:  28351989
• Autophagy-related (ATG) 11, ATG9 and the phosphatidylinositol 3-kinase control ATG2-mediated formation of autophagosomes in Arabidopsis.   DOI:  10.1007/s00299-018-2258-9 ;  PMID:  29350244
• The Local Phosphate Deficiency Response Activates Endoplasmic Reticulum Stress-Dependent Autophagy.   DOI:  10.1104/pp.18.01379 ;  PMID:  30510038
• Salicylic acid is a key player of Arabidopsis autophagy mutant susceptibility to the necrotrophic bacterium Dickeya dadantii.   DOI:  10.1038/s41598-021-83067-6 ;  PMID:  33574453
• Autophagy mutants show delayed chloroplast development during de-etiolation in carbon limiting conditions.   DOI:  10.1111/tpj.15452 ;  PMID:  34365695
• A molecular link between autophagy and circadian rhythm in plants.   DOI:  10.1111/jipb.13250 ;  PMID:  35297190
• The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy in Arabidopsis thaliana.   DOI:  10.3389/fpls.2023.1160162 ;  PMID:  37008475
• Arabidopsis AUTOPHAGY-RELATED2 is essential for ATG18a and ATG9 trafficking during autophagosome closure.   DOI:  10.1093/plphys/kiad287 ;  PMID:  37195145

Sequences: