Gene Details:

• Gene ID: AT3G19170
• Gene Symbol: ATPREP1, ATZNMP, PREP1
• Gene Name: presequence protease 1, presequence protease 1
• Description: presequence protease 1;(source:Araport11)
• TAIR Accession: locus:2094138
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G19170.1     AT3G19170.2

Plant Ontology Annotations:

• PO:0005679  — plant epidermis — dermal tissue (exact), epidermal layer (exact), epidermides (exact, plural), epidermis (Spanish, exact), epidermises (exact, plural), portion of epidermal tissue (exact), 表皮 (Japanese, exact), multiseriate epidermis (related)
• PO:0009001  — fruit — frucht (exact, German), fruto (exact, Spanish), 果実 (exact, Japanese), coenocarp (narrow), syncarp (narrow), aggregate fruit (broad), compound fruit (broad), dehiscent fruit (broad), diaspore (broad), indehiscent fruit (broad), multiple fruit (broad), propagule (broad)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)

Gene Ontology:

• GO:0009570  — located in — chloroplast stroma
• GO:0016485  — involved in — protein processing
• GO:0004222  — enables — metalloendopeptidase activity
• GO:0005739  — located in — mitochondrion
• GO:0009941  — located in — chloroplast envelope
• GO:0009507  — located in — chloroplast
• GO:0016485  — acts upstream of or within — protein processing
• GO:0046872  — enables — metal ion binding
• GO:0048046  — located in — apoplast
• GO:0005515  — enables — protein binding
• GO:0005739  — is active in — mitochondrion
• GO:0005829  — located in — cytosol
• GO:0009507  — is active in — chloroplast

Function-related keywords:

• plant epidermis ,  fruit ,  flower

Literature:

• Isolation and identification of a novel mitochondrial metalloprotease (PreP) that degrades targeting presequences in plants.   DOI:  10.1074/jbc.M205500200 ;  PMID:  12138166
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Characterization of a novel zinc metalloprotease involved in degrading targeting peptides in mitochondria and chloroplasts.   DOI:  10.1046/j.1365-313x.2003.01904.x ;  PMID:  14617063
• A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction.   DOI:  10.1104/pp.103.033910 ;  PMID:  14730085
• When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress.   DOI:  10.1104/pp.103.033431 ;  PMID:  15047901
• Cell-specific protein profiling in Arabidopsis thaliana trichomes: identification of trichome-located proteins involved in sulfur metabolism and detoxification.   DOI:  10.1016/j.phytochem.2004.03.026 ;  PMID:  15276459
• Catalysis, subcellular localization, expression and evolution of the targeting peptides degrading protease, AtPreP2.   DOI:  10.1093/pcp/pci107 ;  PMID:  15827031
• The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses.   DOI:  10.1002/pmic.200500543 ;  PMID:  16502469
• Downregulation of ClpR2 leads to reduced accumulation of the ClpPRS protease complex and defects in chloroplast biogenesis in Arabidopsis.   DOI:  10.1105/tpc.106.042861 ;  PMID:  16766689
• Light has a specific role in modulating Arabidopsis gene expression at low temperature.   DOI:  10.1186/1471-2229-8-13 ;  PMID:  18230142
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis.   DOI:  10.1104/pp.108.124545 ;  PMID:  18633119
• Deletion of an organellar peptidasome PreP affects early development in Arabidopsis thaliana.   DOI:  10.1007/s11103-009-9534-6 ;  PMID:  19701724
• Large scale comparative proteomics of a chloroplast Clp protease mutant reveals folding stress, altered protein homeostasis, and feedback regulation of metabolism.   DOI:  10.1074/mcp.M900104-MCP200 ;  PMID:  19423572
• Species specific amino acid sequence-protein local structure relationships: An analysis in the light of a structural alphabet.   DOI:  10.1016/j.jtbi.2011.01.047 ;  PMID:  21333657
• Proteomic analyses of apoplastic proteins from germinating Arabidopsis thaliana pollen.   DOI:  10.1016/j.bbapap.2011.07.013 ;  PMID:  21798377
• A novel mitochondrial and chloroplast peptidasome, PreP.   DOI:  10.1111/j.1399-3054.2011.01531.x ;  PMID:  21995547
• A proteomic analysis of Arabidopsis thaliana seedling responses to 3-oxo-octanoyl-homoserine lactone, a bacterial quorum-sensing signal.   DOI:  10.1016/j.bbrc.2012.09.044 ;  PMID:  22995300
• Accumulation of endogenous peptides triggers a pathogen stress response in Arabidopsis thaliana.   DOI:  10.1111/tpj.14100 ;  PMID:  30242930
• Autocatalytic Processing and Substrate Specificity of Arabidopsis Chloroplast Glutamyl Peptidase.   DOI:  10.1104/pp.20.00752 ;  PMID:  32663165
• The CLP and PREP protease systems coordinate maturation and degradation of the chloroplast proteome in Arabidopsis thaliana.   DOI:  10.1111/nph.18426 ;  PMID:  35946374
• Isolation and identification of a novel mitochondrial metalloprotease (PreP) that degrades targeting presequences in plants.   DOI:  10.1074/jbc.M205500200 ;  PMID:  12138166
• Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.   DOI:  10.1021/pr034025j ;  PMID:  12938931
• Characterization of a novel zinc metalloprotease involved in degrading targeting peptides in mitochondria and chloroplasts.   DOI:  10.1046/j.1365-313x.2003.01904.x ;  PMID:  14617063
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209
• Cell-specific protein profiling in Arabidopsis thaliana trichomes: identification of trichome-located proteins involved in sulfur metabolism and detoxification.   DOI:  10.1016/j.phytochem.2004.03.026 ;  PMID:  15276459
• The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses.   DOI:  10.1002/pmic.200500543 ;  PMID:  16502469
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.   DOI:  10.1016/j.phytochem.2008.04.007 ;  PMID:  18538804
• Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis.   DOI:  10.1104/pp.108.124545 ;  PMID:  18633119
• The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.   DOI:  10.1074/mcp.M500180-MCP200 ;  PMID:  16207701
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464

Sequences: