Information report for AT3G18290
Gene Details
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Functional Descriptions
- PO:0025195 — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- GO:0010106 — acts upstream of or within — cellular response to iron ion starvation
- GO:0005515 — enables — protein binding
- GO:0010106 — involved in — cellular response to iron ion starvation
- GO:0006511 — involved in — ubiquitin-dependent protein catabolic process
- GO:0009793 — acts upstream of or within — embryo development ending in seed dormancy
- GO:0071456 — acts upstream of or within — cellular response to hypoxia
- GO:0061630 — enables — ubiquitin protein ligase activity
- GO:0060586 — involved in — multicellular organismal-level iron ion homeostasis
Functional Keywords
Literature and News
- Evaluation and classification of RING-finger domains encoded by the Arabidopsis genome. DOI: 10.1186/gb-2002-3-4-research0016 ; PMID: 11983057
- Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. DOI: 10.1074/jbc.M308435200 ; PMID: 14576160
- The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis. DOI: 10.1074/jbc.M313350200 ; PMID: 14722088
- ABA activates ADPR cyclase and cADPR induces a subset of ABA-responsive genes in Arabidopsis. DOI: 10.1111/j.1365-313X.2004.02055.x ; PMID: 15086800
- Identification of genes required for embryo development in Arabidopsis. DOI: 10.1104/pp.104.045179 ; PMID: 15266054
- Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis. DOI: 10.1104/pp.104.052423 ; PMID: 15644464
- Cis-regulatory element based targeted gene finding: genome-wide identification of and abiotic stress-responsive genes in Arabidopsis thaliana. DOI: 10.1093/bioinformatics/bti490 ; PMID: 15890746
- Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. DOI: 10.1104/pp.108.126375 ; PMID: 18775970
- Identification, cloning and characterization of sis7 and sis10 sugar-insensitive mutants of Arabidopsis. DOI: 10.1186/1471-2229-8-104 ; PMID: 18854047
- The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots. DOI: 10.1105/tpc.110.074096 ; PMID: 20675571
- Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis. DOI: 10.1104/pp.110.168120 ; PMID: 21139083
- The transcriptional response of Arabidopsis leaves to Fe deficiency. DOI: 10.3389/fpls.2013.00276 ; PMID: 23888164
- Endogenous Arabidopsis messenger RNAs transported to distant tissues. DOI: 10.1038/nplants.2015.25 ; PMID: 27247031
- Chromate alters root system architecture and activates expression of genes involved in iron homeostasis and signaling in Arabidopsis thaliana. DOI: 10.1007/s11103-014-0210-0 ; PMID: 24928490
- bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. DOI: 10.1093/jxb/erx043 ; PMID: 28369511
- BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana. DOI: 10.1039/c7mt00152e ; PMID: 28620661
- Genome-wide analysis of gene expression profiling revealed that COP9 signalosome is essential for correct expression of Fe homeostasis genes in Arabidopsis. DOI: 10.1007/s10534-017-0036-8 ; PMID: 28744713
- The E3 ligase BRUTUS facilitates degradation of VOZ1/2 transcription factors. DOI: 10.1111/pce.13363 ; PMID: 29878379
- Iron and Phosphate Deficiency Regulators Concertedly Control Coumarin Profiles in Arabidopsis thaliana Roots During Iron, Phosphate, and Combined Deficiencies. DOI: 10.3389/fpls.2019.00113 ; PMID: 30804973
- Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis. DOI: 10.1111/nph.16071 ; PMID: 31334862
- Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. DOI: 10.1105/tpc.19.00463 ; PMID: 31519798
- The iron deficiency response in Arabidopsis thaliana requires the phosphorylated transcription factor URI. DOI: 10.1073/pnas.1916892116 ; PMID: 31776249
- The Transcription Factor bHLH121 Interacts with bHLH105 (ILR3) and Its Closest Homologs to Regulate Iron Homeostasis in Arabidopsis. DOI: 10.1105/tpc.19.00541 ; PMID: 31776233
- Alteration of iron responsive gene expression in Arabidopsis glutaredoxin S17 loss of function plants with or without iron stress. DOI: 10.1080/15592324.2020.1758455 ; PMID: 32351167
- Sulphur availability modulates Arabidopsis thaliana responses to iron deficiency. DOI: 10.1371/journal.pone.0237998 ; PMID: 32817691
- Bacterial effector targeting of a plant iron sensor facilitates iron acquisition and pathogen colonization. DOI: 10.1093/plcell/koab075 ; PMID: 33751120
- IRON MAN interacts with BRUTUS to maintain iron homeostasis in Arabidopsis. DOI: 10.1073/pnas.2109063118 ; PMID: 34548401
- Altered metal distribution in the sr45-1 Arabidopsis mutant causes developmental defects. DOI: 10.1111/tpj.15740 ; PMID: 35305053
- The Iron Deficiency-Regulated Small Protein Effector FEP3/IRON MAN1 Modulates Interaction of BRUTUS-LIKE1 With bHLH Subgroup IVc and POPEYE Transcription Factors. DOI: 10.3389/fpls.2022.930049 ; PMID: 35755670
- ELONGATED HYPOCOTYL 5 regulates BRUTUS and affects iron acquisition and homeostasis in Arabidopsis thaliana. DOI: 10.1111/tpj.16191 ; PMID: 36920240
- Repertoire of plant RING E3 ubiquitin ligases revisited: New groups counting gene families and single genes. DOI: 10.1371/journal.pone.0203442 ; PMID: 30169501
Gene Resources
Homologs
- Fragaria vesca mrna24941.1-v1.0-hybrid
- Lactuca sativa Lsat_1_v5_gn_5_61420, Lsat_1_v5_gn_5_45920
- Malus domestica MDP0000181937, MDP0000232929, MDP0000124187
- Oryza sativa HRZ1, OsHRZ2, SDEL1;OsMSRFP, OsRZFP34, DCA1, OsSRFP1;SDEL2
Sequences
cDNA Sequence
- >AT3G18290.1
AAAATTTACAAGGATCGTATAATACTACTAACAGTTTTTTTTAAATATTTTCCAGATAAACATTAATAAAACGATAAAAGGCAAAAAATAAAAAAGAAAAGAAAGCAAAAGCAAAATCAAAATCGATATATCAGACAACGCCTCGACCTTTCTTTCTTTTTTTCCTTCTCATCGTCTCCGTTGAACAACACCACACAAACACCAGAAGAACACCAGATAATTCCCATGGTGAACCGAGCTCAGATTTGAAAATTGAAGGTCGTAGACGAATCATAAGGAAAGAGAGAAGTGGTTTGAGATTTCTTTTTTGACGGACGAAAACGGAGATAAGCTTTGGGGGAAATGGCGACGCCGTTACCAGATTTTGAGACGGCGAGAGGCGGCGGAGCAGTGGCGTCTTCTTCAACCACGGTTCTTCCGAGTTCTGTGTCTTCTTCTTCTTCTTCATCTCGTCCGTTGCCTGTGGCGAATTCGTTCTCGGATGACGCGGAAGAGATTTCTCCGATCCTGATTTTCTTGTTCTTTCATAAGGCAGTATGTAGTGAGCTTGAAGCTCTTCATAGATTGGCTCTTGAGTTTGCTACTGGTCACCATGTCGATCTCCGGCTGCTTCGTGAACGGTACCGGTTCTTGAGATCCATCTATAAGCATCACTGCAATGCCGAAGACGAGGTGATATTTTCAGCTCTTGACATACGTGTGAAGAATGTAGCGCAAACATATTCTCTTGAACACAAGGGGGAAAGCAATCTTTTCGATCATCTCTTTGAGCTGCTGAATTCTGCCACGGAAACTGATGAAAGTTACCGAAGGGAGTTGGCTCGTTCTACCGGAGCACTTCAGACTTCTGTTAGCCAGCACTTGGCGAAAGAACAGAAACAGGTGTTCCCCTTACTTATTGAGAAATTCAAGTATGAGGAGCAAGCTTACATAGTCTGGCGGTTTCTCTGCAGTATTCCTGTGAATATGCTTGCTGTGTTCTTGCCATGGATTTCTTCTTCCATTTCAGTAGATGAAAGCAAGGAGATGCAAACGTGCTTAAAGAAGATAGTTCCAGGCGAGAAGCTCCTTCAGCAGGTTATTTTCACCTGGCTGGGAGGGAAAAGCAATACCGTGGCTTCGTGTCGCATTGAAGATTCTATGTTCCAGTGCTGTCTAGATTCTTCTAGCAGCATGCTTCCTTGTAAAGCAAGTAGAGAACAGTGCGCATGTGAGGGTTCCAAGATTGGGAAGAGAAAGTACCCAGAGCTTACTAACTTTGGCTCATCTGATACTCTGCACCCAGTTGATGAGATAAAGCTCTGGCACAAGTCAATCAACAAGGAGATGAAAGAAATAGCCGATGAGGCTAGGAAGATTCAGCTGTCTGGAGATTTTTCGGATTTATCGGCATTTGATGAACGCTTACAATATATTGCTGAAGTGTGCATCTTCCATAGTCTTGCAGAGGACAAGATCATATTTCCAGCTGTAGATGGAGAGTTTTCATTTTCTGAAGAGCACGATGAAGAAGAAAATCAGTTTAACGAGTTTCGATGCTTAATTGAAAATATCAAGAGTGCTGGAGCCTCTTCTACTTCCGCTGCCGAATTTTACACTAAGCTGTGCTCACATGCTGATCAAATAATGGAAACTATTCAAAGACACTTCCATAACGAGGAAATTCAGGTGCTACCCCTTGCACGAAAGAACTTCAGCTTCAAAAGACAACAAGAACTTCTCTACCAAAGCCTGTGTATAATGCCATTGAGACTAATTGAACGAGTTTTGCCATGGTTGACGGCATCTTTAACAGAAGATGAAGCTAAGAATTTTCTGAAGAACTTGCAAGCTGGAGCACCTAAATCGGATGTTGCTCTCGTTACTCTTTTCTCTGGTTGGGCTTGCAAAGGACGCAAAGCCGGGGAATGCTTGTCTCCAAACGGGAATGGTTTATGCCCTGTGAAAACACTAAGCAACATTAAAGAAGTCAACCTTCAGTCATGTAATGCTTGTGCGTCTGTTCCATGCACGAGTAGGAGTACAAAATCGTGTTGCCAGCATCAAGATAAAAGGCCAGCTAAGCGAACTGCTGTATTGTCTTGTGAAAAAAAAACCACCCCTCACTCGACAGAAGTTGCAAATGGGTGCAAGCCATCTGGAAATGGTAGGTCATGCTGTGTTCCGGATCTCGGAGTTAACAATAATTGTCTGGAACTTGGTTCTCTTCCAGCAGCTAAAGCTATGAGATCTTCTTCGCTAAACTCTGCTGCACCCGCTCTTAATTCCAGCCTCTTTATTTGGGAAATGGATAGTAACAGCTTTGGTACTGGACATGCTGAGCGGCCAGTTGCTACAATATTCAAGTTTCACAAGGCCATAAGCAAAGATCTAGAGTTTCTTGATGTTGAATCTGGAAAGCTCATTGATTGCGATGGAACATTTATTCGTCAATTTATCGGTCGATTTCACCTACTCTGGGGTTTCTACAAGGCTCATAGTAATGCAGAAGATGACATCCTATTTCCAGCTCTAGAATCGAAGGAGACACTTCACAATGTCAGTCACTCTTACACGCTCGACCATAAACAGGAGGAGAAGTTGTTTGGAGATATTTATAGTGTCCTTACCGAACTTTCAATTCTTCATGAGAAGTTACAGAGTGATTCTATGATGGAGGACATAGCTCAAACTGACACTGTTCGGACGGATATCGATAACGGTGACTGCAACAAGAAATACAATGAACTGGCTACAAAGCTACAGGGGATGTGCAAATCCATTAAAATCACTTTGGATCAGCACATTTTCTTGGAGGAACTGGAGCTTTGGCCTCTATTTGACAAACACTTCTCCATTCAAGAGCAAGACAAGATTGTGGGTCGTATAATCGGAACAACGGGTGCTGAAGTTCTTCAATCTATGTTACCATGGGTGACGTCTGCCCTTTCTGAAGATGAGCAAAACAGAATGATGGATACCTGGAAGCAGGCAACCAAGAACACAATGTTCGATGAATGGCTTAATGAATGCTGGAAAGGATCACCCGACTCATCCTCAACAGAAACATCCAAACCTAGTCCACAGAAAGATAATGATCATCAAGAAATCTTGGACCAAAGTGGTGAACTATTTAAGCCAGGGTGGAAAGATATTTTCCGCATGAACCAGAATGAACTAGAGGCTGAAATCAGGAAGGTCTATCAGGACTCAACACTTGATCCGAGGAGAAAAGATTATCTCGTACAGAATTGGAGGACCAGTCGATGGATTGCGGCTCAGCAAAAGTTACCTAAGGAAGCAGAAACTGCAGTAAATGGTGATGTTGAACTTGGATGTTCCCCGTCTTTTCGGGATCCCGAGAAGCAGATATATGGATGCGAGCATTACAAGCGTAACTGCAAGCTTCGAGCTGCTTGTTGTGATCAGTTGTTCACTTGTAGGTTTTGCCATGACAAAGTAAGCGACCACTCCATGGATAGAAAATTGGTGACGGAAATGCTCTGTATGCGGTGCCTCAAGGTGCAACCTGTTGGTCCCATCTGCACAACACCTTCATGCGACGGATTCCCAATGGCAAAGCACTATTGCAGTATTTGCAAACTTTTTGATGATGAAAGGGCCGTTTACCACTGTCCATTCTGCAACCTTTGCCGGGTCGGGGAAGGACTAGGAATCGATTTTTTCCATTGCATGACATGTAACTGTTGCCTAGGGATGAAATTAGTAAACCACAAGTGCCTCGAGAAGAGCCTCGAGACAAATTGCCCCATCTGCTGCGAATTTCTTTTCACATCGAGTGAAGCAGTTAGAGCCTTACCATGTGGTCACTACATGCACTCAGCTTGCTTCCAGGCTTACACTTGCAGTCACTACACATGTCCAATCTGTGGAAAATCATTAGGAGATATGGCTGTTTATTTTGGTATGCTTGATGCACTGTTAGCTGCAGAAGAACTTCCAGAGGAATACAAAAATCGCTGTCAGGACATTCTATGTAATGATTGTGAACGCAAAGGAACTACACGGTTCCATTGGTTGTACCATAAATGTGGTAGCTGTGGTTCTTACAATACCCGGGTGATCAAGTCCGAAACAATCCCCCCGGACTGCTCAACCTCATCCTGAAAACACCAAGAGGTTTCACTCACTTGTTACTCTCTTTTTTTCTTTCCTTTTTTCGGGTTTTACCCTCTGTTTCGCACAACAATGTGAAGAAGCCCGTTGATAGATTTTTTTTTTGTATAGTCTCTGAGATATTAAGATTTTGAAGAGTCTTTATTTAGGTTACCTTACTATACATTTTGGCTTGAACAAAGCCAAAAAATTTCGTTTGTTTCTGGAACATCCCATACCGTCATCCTCTTTCTTCCACATAATCCGCTATTTGTTTTTGCATTAAGCTGAGACTTTTTCTTTGAAGAGTGTAAATAGTTAACAATTTTTAATAGAAAACTTTTTTCCACTCTTCGTATCTGACTATACTATTTCTTATTGTTGATGTCAAGAAAAAAAA
CDS Sequence
- >AT3G18290.1
ATGGCGACGCCGTTACCAGATTTTGAGACGGCGAGAGGCGGCGGAGCAGTGGCGTCTTCTTCAACCACGGTTCTTCCGAGTTCTGTGTCTTCTTCTTCTTCTTCATCTCGTCCGTTGCCTGTGGCGAATTCGTTCTCGGATGACGCGGAAGAGATTTCTCCGATCCTGATTTTCTTGTTCTTTCATAAGGCAGTATGTAGTGAGCTTGAAGCTCTTCATAGATTGGCTCTTGAGTTTGCTACTGGTCACCATGTCGATCTCCGGCTGCTTCGTGAACGGTACCGGTTCTTGAGATCCATCTATAAGCATCACTGCAATGCCGAAGACGAGGTGATATTTTCAGCTCTTGACATACGTGTGAAGAATGTAGCGCAAACATATTCTCTTGAACACAAGGGGGAAAGCAATCTTTTCGATCATCTCTTTGAGCTGCTGAATTCTGCCACGGAAACTGATGAAAGTTACCGAAGGGAGTTGGCTCGTTCTACCGGAGCACTTCAGACTTCTGTTAGCCAGCACTTGGCGAAAGAACAGAAACAGGTGTTCCCCTTACTTATTGAGAAATTCAAGTATGAGGAGCAAGCTTACATAGTCTGGCGGTTTCTCTGCAGTATTCCTGTGAATATGCTTGCTGTGTTCTTGCCATGGATTTCTTCTTCCATTTCAGTAGATGAAAGCAAGGAGATGCAAACGTGCTTAAAGAAGATAGTTCCAGGCGAGAAGCTCCTTCAGCAGGTTATTTTCACCTGGCTGGGAGGGAAAAGCAATACCGTGGCTTCGTGTCGCATTGAAGATTCTATGTTCCAGTGCTGTCTAGATTCTTCTAGCAGCATGCTTCCTTGTAAAGCAAGTAGAGAACAGTGCGCATGTGAGGGTTCCAAGATTGGGAAGAGAAAGTACCCAGAGCTTACTAACTTTGGCTCATCTGATACTCTGCACCCAGTTGATGAGATAAAGCTCTGGCACAAGTCAATCAACAAGGAGATGAAAGAAATAGCCGATGAGGCTAGGAAGATTCAGCTGTCTGGAGATTTTTCGGATTTATCGGCATTTGATGAACGCTTACAATATATTGCTGAAGTGTGCATCTTCCATAGTCTTGCAGAGGACAAGATCATATTTCCAGCTGTAGATGGAGAGTTTTCATTTTCTGAAGAGCACGATGAAGAAGAAAATCAGTTTAACGAGTTTCGATGCTTAATTGAAAATATCAAGAGTGCTGGAGCCTCTTCTACTTCCGCTGCCGAATTTTACACTAAGCTGTGCTCACATGCTGATCAAATAATGGAAACTATTCAAAGACACTTCCATAACGAGGAAATTCAGGTGCTACCCCTTGCACGAAAGAACTTCAGCTTCAAAAGACAACAAGAACTTCTCTACCAAAGCCTGTGTATAATGCCATTGAGACTAATTGAACGAGTTTTGCCATGGTTGACGGCATCTTTAACAGAAGATGAAGCTAAGAATTTTCTGAAGAACTTGCAAGCTGGAGCACCTAAATCGGATGTTGCTCTCGTTACTCTTTTCTCTGGTTGGGCTTGCAAAGGACGCAAAGCCGGGGAATGCTTGTCTCCAAACGGGAATGGTTTATGCCCTGTGAAAACACTAAGCAACATTAAAGAAGTCAACCTTCAGTCATGTAATGCTTGTGCGTCTGTTCCATGCACGAGTAGGAGTACAAAATCGTGTTGCCAGCATCAAGATAAAAGGCCAGCTAAGCGAACTGCTGTATTGTCTTGTGAAAAAAAAACCACCCCTCACTCGACAGAAGTTGCAAATGGGTGCAAGCCATCTGGAAATGGTAGGTCATGCTGTGTTCCGGATCTCGGAGTTAACAATAATTGTCTGGAACTTGGTTCTCTTCCAGCAGCTAAAGCTATGAGATCTTCTTCGCTAAACTCTGCTGCACCCGCTCTTAATTCCAGCCTCTTTATTTGGGAAATGGATAGTAACAGCTTTGGTACTGGACATGCTGAGCGGCCAGTTGCTACAATATTCAAGTTTCACAAGGCCATAAGCAAAGATCTAGAGTTTCTTGATGTTGAATCTGGAAAGCTCATTGATTGCGATGGAACATTTATTCGTCAATTTATCGGTCGATTTCACCTACTCTGGGGTTTCTACAAGGCTCATAGTAATGCAGAAGATGACATCCTATTTCCAGCTCTAGAATCGAAGGAGACACTTCACAATGTCAGTCACTCTTACACGCTCGACCATAAACAGGAGGAGAAGTTGTTTGGAGATATTTATAGTGTCCTTACCGAACTTTCAATTCTTCATGAGAAGTTACAGAGTGATTCTATGATGGAGGACATAGCTCAAACTGACACTGTTCGGACGGATATCGATAACGGTGACTGCAACAAGAAATACAATGAACTGGCTACAAAGCTACAGGGGATGTGCAAATCCATTAAAATCACTTTGGATCAGCACATTTTCTTGGAGGAACTGGAGCTTTGGCCTCTATTTGACAAACACTTCTCCATTCAAGAGCAAGACAAGATTGTGGGTCGTATAATCGGAACAACGGGTGCTGAAGTTCTTCAATCTATGTTACCATGGGTGACGTCTGCCCTTTCTGAAGATGAGCAAAACAGAATGATGGATACCTGGAAGCAGGCAACCAAGAACACAATGTTCGATGAATGGCTTAATGAATGCTGGAAAGGATCACCCGACTCATCCTCAACAGAAACATCCAAACCTAGTCCACAGAAAGATAATGATCATCAAGAAATCTTGGACCAAAGTGGTGAACTATTTAAGCCAGGGTGGAAAGATATTTTCCGCATGAACCAGAATGAACTAGAGGCTGAAATCAGGAAGGTCTATCAGGACTCAACACTTGATCCGAGGAGAAAAGATTATCTCGTACAGAATTGGAGGACCAGTCGATGGATTGCGGCTCAGCAAAAGTTACCTAAGGAAGCAGAAACTGCAGTAAATGGTGATGTTGAACTTGGATGTTCCCCGTCTTTTCGGGATCCCGAGAAGCAGATATATGGATGCGAGCATTACAAGCGTAACTGCAAGCTTCGAGCTGCTTGTTGTGATCAGTTGTTCACTTGTAGGTTTTGCCATGACAAAGTAAGCGACCACTCCATGGATAGAAAATTGGTGACGGAAATGCTCTGTATGCGGTGCCTCAAGGTGCAACCTGTTGGTCCCATCTGCACAACACCTTCATGCGACGGATTCCCAATGGCAAAGCACTATTGCAGTATTTGCAAACTTTTTGATGATGAAAGGGCCGTTTACCACTGTCCATTCTGCAACCTTTGCCGGGTCGGGGAAGGACTAGGAATCGATTTTTTCCATTGCATGACATGTAACTGTTGCCTAGGGATGAAATTAGTAAACCACAAGTGCCTCGAGAAGAGCCTCGAGACAAATTGCCCCATCTGCTGCGAATTTCTTTTCACATCGAGTGAAGCAGTTAGAGCCTTACCATGTGGTCACTACATGCACTCAGCTTGCTTCCAGGCTTACACTTGCAGTCACTACACATGTCCAATCTGTGGAAAATCATTAGGAGATATGGCTGTTTATTTTGGTATGCTTGATGCACTGTTAGCTGCAGAAGAACTTCCAGAGGAATACAAAAATCGCTGTCAGGACATTCTATGTAATGATTGTGAACGCAAAGGAACTACACGGTTCCATTGGTTGTACCATAAATGTGGTAGCTGTGGTTCTTACAATACCCGGGTGATCAAGTCCGAAACAATCCCCCCGGACTGCTCAACCTCATCCTGA
Protein Sequence
- >AT3G18290.1
MATPLPDFETARGGGAVASSSTTVLPSSVSSSSSSSRPLPVANSFSDDAEEISPILIFLFFHKAVCSELEALHRLALEFATGHHVDLRLLRERYRFLRSIYKHHCNAEDEVIFSALDIRVKNVAQTYSLEHKGESNLFDHLFELLNSATETDESYRRELARSTGALQTSVSQHLAKEQKQVFPLLIEKFKYEEQAYIVWRFLCSIPVNMLAVFLPWISSSISVDESKEMQTCLKKIVPGEKLLQQVIFTWLGGKSNTVASCRIEDSMFQCCLDSSSSMLPCKASREQCACEGSKIGKRKYPELTNFGSSDTLHPVDEIKLWHKSINKEMKEIADEARKIQLSGDFSDLSAFDERLQYIAEVCIFHSLAEDKIIFPAVDGEFSFSEEHDEEENQFNEFRCLIENIKSAGASSTSAAEFYTKLCSHADQIMETIQRHFHNEEIQVLPLARKNFSFKRQQELLYQSLCIMPLRLIERVLPWLTASLTEDEAKNFLKNLQAGAPKSDVALVTLFSGWACKGRKAGECLSPNGNGLCPVKTLSNIKEVNLQSCNACASVPCTSRSTKSCCQHQDKRPAKRTAVLSCEKKTTPHSTEVANGCKPSGNGRSCCVPDLGVNNNCLELGSLPAAKAMRSSSLNSAAPALNSSLFIWEMDSNSFGTGHAERPVATIFKFHKAISKDLEFLDVESGKLIDCDGTFIRQFIGRFHLLWGFYKAHSNAEDDILFPALESKETLHNVSHSYTLDHKQEEKLFGDIYSVLTELSILHEKLQSDSMMEDIAQTDTVRTDIDNGDCNKKYNELATKLQGMCKSIKITLDQHIFLEELELWPLFDKHFSIQEQDKIVGRIIGTTGAEVLQSMLPWVTSALSEDEQNRMMDTWKQATKNTMFDEWLNECWKGSPDSSSTETSKPSPQKDNDHQEILDQSGELFKPGWKDIFRMNQNELEAEIRKVYQDSTLDPRRKDYLVQNWRTSRWIAAQQKLPKEAETAVNGDVELGCSPSFRDPEKQIYGCEHYKRNCKLRAACCDQLFTCRFCHDKVSDHSMDRKLVTEMLCMRCLKVQPVGPICTTPSCDGFPMAKHYCSICKLFDDERAVYHCPFCNLCRVGEGLGIDFFHCMTCNCCLGMKLVNHKCLEKSLETNCPICCEFLFTSSEAVRALPCGHYMHSACFQAYTCSHYTCPICGKSLGDMAVYFGMLDALLAAEELPEEYKNRCQDILCNDCERKGTTRFHWLYHKCGSCGSYNTRVIKSETIPPDCSTSS