Gene Details:
- Gene ID: AT3G18000
- Gene Symbol: AtPMT1, DPR2, NMT1, PEAMT, PEAMT1, XPL1
- Gene Name: Phosphoethanolamine methyltransferase1, N-METHYLTRANSFERASE 1, XIPOTL 1
- Description: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein;(source:Araport11)
- Description: Derives_from AT3G18000;(source:Araport11)
- TAIR Accession: locus:2088535
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0006081 — primary root apical meristem — meristema apical de la raíz primaria (Spanish, exact), 一次根頂端分裂組織 (Japanese, exact), apical meristem of primary root (related), embryonic root meristem (related)
- PO:0025257 — primary root elongation zone — zona de elongación de la raíz primaria (Spanish, exact), 一次根伸長帯(層) (Japanese, exact)
- PO:0025195 — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
Gene Ontology:
- GO:0009860 — acts upstream of or within — pollen tube growth
- GO:0042425 — acts upstream of or within — choline biosynthetic process
- GO:0006656 — involved in — phosphatidylcholine biosynthetic process
- GO:0000234 — enables — phosphoethanolamine N-methyltransferase activity
- GO:0010183 — acts upstream of or within — pollen tube guidance
- GO:0009826 — acts upstream of or within — unidimensional cell growth
- GO:0048528 — acts upstream of or within — post-embryonic root development
- GO:0006656 — acts upstream of or within — phosphatidylcholine biosynthetic process
- GO:0052667 — enables — phosphomethylethanolamine N-methyltransferase activity
- GO:0005737 — located in — cytoplasm
- GO:0008168 — enables — methyltransferase activity
- GO:0009555 — acts upstream of or within — pollen development
Germplasm Phenotype:
- CS65881 — The mutation causes defective pollen tube growth in the pistil.
Function-related keywords:
Literature:
- The xipotl mutant of Arabidopsis reveals a critical role for phospholipid metabolism in root system development and epidermal cell integrity. DOI: 10.1105/tpc.103.018648 ; PMID: 15295103
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. DOI: 10.1104/pp.108.126375 ; PMID: 18775970
- Penetration of the stigma and style elicits a novel transcriptome in pollen tubes, pointing to genes critical for growth in a pistil. DOI: 10.1371/journal.pgen.1000621 ; PMID: 19714218
- Identification of phosphomethylethanolamine N-methyltransferase from Arabidopsis and its role in choline and phospholipid metabolism. DOI: 10.1074/jbc.M110.112151 ; PMID: 20650897
- Identification of genes involved in the ACC-mediated control of root cell elongation in Arabidopsis thaliana. DOI: 10.1186/1471-2229-12-208 ; PMID: 23134674
- Acyl-lipid metabolism. DOI: 10.1199/tab.0161 ; PMID: 23505340
- Conformational changes in the di-domain structure of Arabidopsis phosphoethanolamine methyltransferase leads to active-site formation. DOI: 10.1074/jbc.RA117.000106 ; PMID: 29084845
- NMT1 and NMT3 N-Methyltransferase Activity Is Critical to Lipid Homeostasis, Morphogenesis, and Reproduction. DOI: 10.1104/pp.18.00457 ; PMID: 29777000
- A pair of phospho-base methyltransferases important for phosphatidylcholine biosynthesis in Arabidopsis. DOI: 10.1111/tpj.14090 ; PMID: 30218542
- Loss of Phosphoethanolamine N-Methyltransferases Abolishes Phosphatidylcholine Synthesis and Is Lethal. DOI: 10.1104/pp.18.00694 ; PMID: 30381317
- A Methyltransferase Trio Essential for Phosphatidylcholine Biosynthesis and Growth. DOI: 10.1104/pp.18.01408 ; PMID: 30518673
- Non-specific phospholipases C, NPC2 and NPC6, are required for root growth in Arabidopsis. DOI: 10.1111/tpj.14494 ; PMID: 31400172
- Phosphoethanolamine N-methyltransferase 1 contributes to maintenance of root apical meristem by affecting ROS and auxin-regulated cell differentiation in Arabidopsis. DOI: 10.1111/nph.16028 ; PMID: 31246280
- The phospho-base N-methyltransferases PMT1 and PMT2 produce phosphocholine for leaf growth in phosphorus-starved Arabidopsis. DOI: 10.1093/jxb/erab436 ; PMID: 35560207
Sequences:
cDNA Sequence
- >AT3G18000.1
ACACTCTTTTCGCTCTCAGATCTGAAACCTTATCTGAATTACATTTCCCCGATTCGACGTTGTGCGAATTGATGCAGCAGAGAGGACGATCCGTCAACCGCAGATCACGAAGCTTCTCTAGATCCAGACTCGCCGTCGAAGGCCACTGAATTACTCTCTCCCCTCTCTTGGCAGATCTTCTTCTTCGTTTTTTCCCGACAAACGACATTTCCGAAATGGCTGCATCGTACGAAGAAGAGCGTGATATTCAGAAGAATTACTGGATAGAGCATTCCGCTGATCTGACTGTTGAAGCTATGATGCTTGACTCGAGAGCTTCTGATCTCGACAAGGAAGAACGTCCTGAGGTACTCTCTTTGCTCCCTCCATATGAAGGCAAATCAGTGTTGGAACTTGGAGCTGGTATTGGTCGTTTCACTGGTGAATTAGCTCAAAAGGCTGGTGAACTCATTGCTCTTGACTTCATTGATAACGTTATCAAGAAGAATGAAAGTATCAATGGGCATTACAAGAATGTCAAGTTTATGTGTGCTGATGTTACATCCCCTGACCTCAAGATCACTGATGGATCTCTTGACTTGATTTTCTCCAACTGGCTGCTCATGTATCTTTCTGACAAAGAGGTGGAGCTTTTGGCAGAAAGGATGGTCGGTTGGATCAAGGTTGGAGGATACATTTTCTTCCGTGAATCTTGCTTCCACCAATCAGGGGACAGTAAGCGGAAATCCAACCCCACTCACTACCGTGAACCCCGTTTCTATTCCAAGGTCTTTCAAGAGTGTCAGACTCGGGATGCTGCTGGAAATTCATTTGAGCTCTCTATGATCGGATGCAAGTGCATTGGAGCTTATGTCAAGAACAAGAAGAATCAGAATCAGATTTGTTGGATATGGCAGAAGGTCAGCTCAGAAAATGACAGAGGCTTCCAACGTTTCTTGGACAATGTCCAATACAAATCCAGTGGAATCCTACGCTATGAGCGTGTCTTTGGCCAAGGGTTTGTGAGCACTGGTGGACTTGAGACAACCAAAGAATTTGTGGAGAAAATGAATCTGAAACCAGGACAGAAAGTCTTAGATGTTGGGTGTGGCATTGGTGGAGGTGACTTCTACATGGCTGAGAAGTTTGATGTTCACGTTGTTGGTATCGATCTTTCTGTCAACATGATCTCTTTCGCATTGGAACGTGCTATTGGACTCAGCTGCTCGGTTGAGTTTGAGGTTGCTGATTGCACCACAAAACACTACCCAGATAATTCGTTTGATGTCATTTACAGCCGTGACACTATTCTGCACATCCAAGACAAACCAGCCTTGTTTAGGACTTTCTTCAAATGGCTTAAACCGGGAGGTAAAGTTCTCATCAGCGACTACTGTAGAAGCCCCAAAACTCCATCTGCTGAGTTTTCAGAGTACATCAAACAGAGAGGATATGATCTCCATGACGTTCAAGCTTATGGACAGATGCTAAAAGACGCTGGCTTCACTGATGTGATCGCAGAGGACCGTACTGATCAGTTTATGCAAGTCCTGAAACGTGAATTAGACAGGGTGGAGAAAGAAAAGGAAAAATTCATCTCCGACTTCTCCAAAGAGGATTACGATGACATTGTTGGAGGATGGAAGTCAAAGCTGGAGAGGTGTGCATCGGATGAGCAGAAATGGGGACTTTTCATCGCCAACAAGAATTAAGCAAATCGAAATCTACTACTTCTATGTTTTCTTCTTTCTTTGTTTGTTCAATAAAAATGTCATTTCCGCTAGGTGATGATATATGCCTGTAGTGTGTTATGTGGACTTGTTGAGTGGTGTTAAATCTTGTTTCCCTTATGTGATATGTAAACCGAATTATGTTTGGTCTTAGTTTATACTCTTTGATTTGAAGAATTTTCTAAATGCATTTGTGTTATGCT
CDS Sequence
- >AT3G18000.1
ATGGCTGCATCGTACGAAGAAGAGCGTGATATTCAGAAGAATTACTGGATAGAGCATTCCGCTGATCTGACTGTTGAAGCTATGATGCTTGACTCGAGAGCTTCTGATCTCGACAAGGAAGAACGTCCTGAGGTACTCTCTTTGCTCCCTCCATATGAAGGCAAATCAGTGTTGGAACTTGGAGCTGGTATTGGTCGTTTCACTGGTGAATTAGCTCAAAAGGCTGGTGAACTCATTGCTCTTGACTTCATTGATAACGTTATCAAGAAGAATGAAAGTATCAATGGGCATTACAAGAATGTCAAGTTTATGTGTGCTGATGTTACATCCCCTGACCTCAAGATCACTGATGGATCTCTTGACTTGATTTTCTCCAACTGGCTGCTCATGTATCTTTCTGACAAAGAGGTGGAGCTTTTGGCAGAAAGGATGGTCGGTTGGATCAAGGTTGGAGGATACATTTTCTTCCGTGAATCTTGCTTCCACCAATCAGGGGACAGTAAGCGGAAATCCAACCCCACTCACTACCGTGAACCCCGTTTCTATTCCAAGGTCTTTCAAGAGTGTCAGACTCGGGATGCTGCTGGAAATTCATTTGAGCTCTCTATGATCGGATGCAAGTGCATTGGAGCTTATGTCAAGAACAAGAAGAATCAGAATCAGATTTGTTGGATATGGCAGAAGGTCAGCTCAGAAAATGACAGAGGCTTCCAACGTTTCTTGGACAATGTCCAATACAAATCCAGTGGAATCCTACGCTATGAGCGTGTCTTTGGCCAAGGGTTTGTGAGCACTGGTGGACTTGAGACAACCAAAGAATTTGTGGAGAAAATGAATCTGAAACCAGGACAGAAAGTCTTAGATGTTGGGTGTGGCATTGGTGGAGGTGACTTCTACATGGCTGAGAAGTTTGATGTTCACGTTGTTGGTATCGATCTTTCTGTCAACATGATCTCTTTCGCATTGGAACGTGCTATTGGACTCAGCTGCTCGGTTGAGTTTGAGGTTGCTGATTGCACCACAAAACACTACCCAGATAATTCGTTTGATGTCATTTACAGCCGTGACACTATTCTGCACATCCAAGACAAACCAGCCTTGTTTAGGACTTTCTTCAAATGGCTTAAACCGGGAGGTAAAGTTCTCATCAGCGACTACTGTAGAAGCCCCAAAACTCCATCTGCTGAGTTTTCAGAGTACATCAAACAGAGAGGATATGATCTCCATGACGTTCAAGCTTATGGACAGATGCTAAAAGACGCTGGCTTCACTGATGTGATCGCAGAGGACCGTACTGATCAGTTTATGCAAGTCCTGAAACGTGAATTAGACAGGGTGGAGAAAGAAAAGGAAAAATTCATCTCCGACTTCTCCAAAGAGGATTACGATGACATTGTTGGAGGATGGAAGTCAAAGCTGGAGAGGTGTGCATCGGATGAGCAGAAATGGGGACTTTTCATCGCCAACAAGAATTAA
Protein Sequence
- >AT3G18000.1
MAASYEEERDIQKNYWIEHSADLTVEAMMLDSRASDLDKEERPEVLSLLPPYEGKSVLELGAGIGRFTGELAQKAGELIALDFIDNVIKKNESINGHYKNVKFMCADVTSPDLKITDGSLDLIFSNWLLMYLSDKEVELLAERMVGWIKVGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYSKVFQECQTRDAAGNSFELSMIGCKCIGAYVKNKKNQNQICWIWQKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPKTPSAEFSEYIKQRGYDLHDVQAYGQMLKDAGFTDVIAEDRTDQFMQVLKRELDRVEKEKEKFISDFSKEDYDDIVGGWKSKLERCASDEQKWGLFIANKN