Gene Details:

• Gene ID: AT3G17360
• Gene Symbol: POK1
• Gene Name: phragmoplast orienting kinesin 1
• Description: phragmoplast orienting kinesin 1;(source:Araport11)
• TAIR Accession: locus:2089000
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G17360.1     AT3G17360.3     AT3G17360.2

Plant Ontology Annotations:

• PO:0000016  — lateral root primordium — portion of lateral root primordium tissue (exact), primordio de raíz lateral (Spanish, exact), 側根原基 (Japanese, exact)
• PO:0000026  — primary root tip — punta de la raíz primaria (Spanish, exact), 一次根端 (Japanese, exact)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)

Gene Ontology:

• GO:0000911  — acts upstream of or within — cytokinesis by cell plate formation
• GO:0000910  — involved in — cytokinesis
• GO:0000281  — involved in — mitotic cytokinesis
• GO:0003777  — enables — microtubule motor activity
• GO:0005515  — enables — protein binding
• GO:0008017  — enables — microtubule binding
• GO:0007018  — involved in — microtubule-based movement

Germplasm Phenotype:

• SALK_067862  — No visible phenotype.
• pok1-1  — No visible phenotype.
• pok1-1/pok2-1  — At seedling stage pok1/pok2 double mutants differ from wild-type by having smaller cotyledons as well as shorter, wider roots and hypocotyls. Adult plants exhibit a dwarfed stature, but all organs are present, although miniaturized. Plants are fertile but produce reduced numbers of seeds. Microscopic observation revealed highly disordered root meristem cell patterns, with most walls lacking parallel or perpendicular alignment to the longitudinal axis of the root and most cells exhibiting irregular shapes. Examination of cell wall patterns suggested that misoriented cell divisions were largely responsible for the irregular cell patterns. In pok1/pok2 double mutant embryos, misplaced cell walls were observed as early as the octant stage of embryogenesis. Throughout embryogenesis, the mispositioning of cell walls continues, eventually giving rise to slightly misshapen mature embryos with a stubby appearance, compared to wild-type. However, incomplete cell walls and wall stubs, a common feature of cytokinesis-defective mutants, were not observed in Toluidine blue-stained sections of double mutant embryos.

Function-related keywords:

• lateral root primordium ,  primary root tip ,  shoot axis apex

Literature:

• Mitosis-specific kinesins in Arabidopsis.   DOI:  10.1016/j.tplants.2006.02.004 ;  PMID:  16530461
• The Arabidopsis thaliana homolog of yeast BRE1 has a function in cell cycle regulation during early leaf and root growth.   DOI:  10.1105/tpc.106.041319 ;  PMID:  17329565
• Putative RopGAPs impact division plane selection and interact with kinesin-12 POK1.   DOI:  10.1038/nplants.2016.120 ;  PMID:  27501519
• Involvement of YODA and mitogen activated protein kinase 6 in Arabidopsis post-embryogenic root development through auxin up-regulation and cell division plane orientation.   DOI:  10.1111/nph.12880 ;  PMID:  24923680
• The localization of PHRAGMOPLAST ORIENTING KINESIN1 at the division site depends on the microtubule-binding proteins TANGLED1 and AUXIN-INDUCED IN ROOT CULTURES9 in Arabidopsis.   DOI:  10.1093/plcell/koac266 ;  PMID:  36005863
• Mitosis-specific kinesins in Arabidopsis.   DOI:  10.1016/j.tplants.2006.02.004 ;  PMID:  16530461

Sequences: