Gene Details:

• Gene ID: AT3G16910
• Gene Symbol: AAE7, ACN1, BZU1
• Gene Name: acyl-activating enzyme 7, ACETATE NON-UTILIZING 1
• Description: acyl-activating enzyme 7;(source:Araport11)
• TAIR Accession: locus:2086122
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G16910.1

Plant Ontology Annotations:

• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)

Gene Ontology:

• GO:0003987  — enables — acetate-CoA ligase activity
• GO:0005829  — located in — cytosol
• GO:0005777  — located in — peroxisome
• GO:0006083  — acts upstream of or within — acetate metabolic process
• GO:0006097  — acts upstream of or within — glyoxylate cycle
• GO:0006083  — involved in — acetate metabolic process
• GO:0031956  — enables — medium-chain fatty acid-CoA ligase activity
• GO:0016208  — enables — AMP binding
• GO:0019605  — involved in — butyrate metabolic process
• GO:0047760  — enables — butyrate-CoA ligase activity
• GO:0005739  — located in — mitochondrion

Germplasm Phenotype:

• CS65814  — No visible phenotype.
• CS65815  — No visible phenotype.
• WiscDsLoxHs036_06B  — Inhibition of shoot and root growth when grown on 1 mM acetate.
• acn1-1  — Exhibited the highest level of resistance to fluoroacetate (FAc). Its germination and growth was unaffected by the toxin in the presence of exogenous sucrose. In the presence of FAc with no sucrose, post-germinative growth may have been slightly affected. When germinated and grown on sodium acetate, the mutant exhibited bleaching at concentrations which had little effect on the wild type.
• acn1-2  — Growth is more severely affected by 3.5 mM acetate than wt plants. Under these conditions, mutant plant growth decreased 50-60% compared to no treatment while wt plant growth decreased 30-40%. Disrupted in thier ability to sense acetate.
• acn1-3  — Disrupted in the ability to sense acetate.
• acs-1 acn1-5  — Serrated leaf margins, short petioles, increased number of rosette leaves, delayed bolting, increased axillary branching, dwarf, delayed senescence, abnormal flower development.

Function-related keywords:

• vascular leaf

Literature:

• Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme a synthetases.   DOI:  10.1104/pp.103.020552 ;  PMID:  12805634
• Comparative analysis of expressed sequence tags from Sesamum indicum and Arabidopsis thaliana developing seeds.   DOI:  10.1023/b:plan.0000004304.22770.e9 ;  PMID:  14682612
• Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis.   DOI:  10.1111/j.1365-313X.2005.02399.x ;  PMID:  15860015
• Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development.   DOI:  10.1105/tpc.106.047688 ;  PMID:  17337630
• Characterization of seed-specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana.   DOI:  10.1111/j.1365-313X.2007.03205.x ;  PMID:  17651367
• Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.   DOI:  10.1105/tpc.107.050989 ;  PMID:  17951448
• Novel proteins, putative membrane transporters, and an integrated metabolic network are revealed by quantitative proteomic analysis of Arabidopsis cell culture peroxisomes.   DOI:  10.1104/pp.108.129999 ;  PMID:  18931141
• Brassica napus cDNAs encoding fatty acyl-CoA synthetase.   DOI:  10.1023/a:1005780529307 ;  PMID:  9106514
• Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.   DOI:  10.1105/tpc.107.050989 ;  PMID:  17951448

Sequences: