Gene Details:

• Gene ID: AT3G16090
• Gene Symbol: AtHRD1A, HRD1A
• Gene Name: homolog of yeast Hrd1, homolog of yeast Hrd1
• Description: RING/U-box superfamily protein;(source:Araport11)
• TAIR Accession: locus:2093422
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G16090.1

Plant Ontology Annotations:

• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:1904276  — acts upstream of or within — regulation of wax biosynthetic process
• GO:0030433  — acts upstream of or within — ubiquitin-dependent ERAD pathway
• GO:0005515  — enables — protein binding

Germplasm Phenotype:

• hrd1a hrd1b  — Endoplasmic reticulum (ER)-associated degradation process is blocked in hrd1a hrd1b double mutant.
• hrd1a hrd1b  — Reduced stem cuticular wax accumulation. Increased leaf and stem cutin monomers.

Function-related keywords:

• plant sperm cell

Literature:

• Evaluation and classification of RING-finger domains encoded by the Arabidopsis genome.   DOI:  10.1186/gb-2002-3-4-research0016 ;  PMID:  11983057
• Conserved endoplasmic reticulum-associated degradation system to eliminate mutated receptor-like kinases in Arabidopsis.   DOI:  10.1073/pnas.1013251108 ;  PMID:  21187394
• EBS7 is a plant-specific component of a highly conserved endoplasmic reticulum-associated degradation system in Arabidopsis.   DOI:  10.1073/pnas.1511724112 ;  PMID:  26371323
• Defects in endoplasmic reticulum-associated degradation (ERAD) increase selenate sensitivity in Arabidopsis.   DOI:  10.1080/15592324.2016.1171451 ;  PMID:  27045899
• PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex.   DOI:  10.1038/s41467-019-11480-7 ;  PMID:  31375683
• Insight into the roles of the ER-associated degradation E3 ubiquitin ligase HRD1 in plant cuticular lipid biosynthesis.   DOI:  10.1016/j.plaphy.2021.08.021 ;  PMID:  34404006
• Repertoire of plant RING E3 ubiquitin ligases revisited: New groups counting gene families and single genes.   DOI:  10.1371/journal.pone.0203442 ;  PMID:  30169501

Sequences: