Gene Details:

• Gene ID: AT3G15950
• Gene Symbol: NAI2
• Gene Name:
• Description: DNA topoisomerase-like protein;(source:Araport11)
• TAIR Accession: locus:2093930
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G15950.1     AT3G15950.2     AT3G15950.4     AT3G15950.5     AT3G15950.3

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0009507  — located in — chloroplast
• GO:0005777  — located in — peroxisome
• GO:0099503  — located in — secretory vesicle
• GO:0009506  — located in — plasmodesma
• GO:0080119  — acts upstream of or within — ER body organization
• GO:0010168  — located in — ER body
• GO:0005634  — located in — nucleus

Germplasm Phenotype:

• CS69076  — ER body deficient mutant. ER bodies are hardly detected in seedlings and roots. The plants do not accumulate NAI2 mRNA and protein.
• CS69077  — ER body deficient mutant. ER bodies are hardly detected in seedlings and roots. The plants do not accumulate NAI2 mRNA and protein.
• CS69078  — ER body deficient mutant. ER bodies are hardly detected in seedlings and roots. The plants do not accumulate NAI2 mRNA and protein.
• SALK_005896C  — Increased root elongation, dry weight, and proline accumulation.
• SALK_043149C  — Increased root elongation, dry weight, and proline accumulation.
• nai2-1  — Mutants lack ER bodies.

Function-related keywords:

• root

Literature:

• Microarray analysis of E2Fa-DPa-overexpressing plants uncovers a cross-talking genetic network between DNA replication and nitrogen assimilation.   DOI:  10.1242/jcs.00715 ;  PMID:  12953064
• An Arabidopsis protein with a novel calcium-binding repeat sequence interacts with TONSOKU/MGOUN3/BRUSHY1 involved in meristem maintenance.   DOI:  10.1093/pcp/pci155 ;  PMID:  15964904
• Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response.   DOI:  10.1007/s00438-006-0177-x ;  PMID:  17061125
• Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.   DOI:  10.1105/tpc.107.050989 ;  PMID:  17951448
• Antagonistic jacalin-related lectins regulate the size of ER body-type beta-glucosidase complexes in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcn075 ;  PMID:  18467340
• NAI2 is an endoplasmic reticulum body component that enables ER body formation in Arabidopsis thaliana.   DOI:  10.1105/tpc.108.059345 ;  PMID:  18780803
• The ER body, a new organelle in Arabidopsis thaliana, requires NAI2 for its formation and accumulates specific beta-glucosidases.   DOI:  10.4161/psb.4.9.9377 ;  PMID:  19847124
• Unique defense strategy by the endoplasmic reticulum body in plants.   DOI:  10.1093/pcp/pcr156 ;  PMID:  22102697
• Identification of two novel endoplasmic reticulum body-specific integral membrane proteins.   DOI:  10.1104/pp.112.207654 ;  PMID:  23166355
• At14a-Like1 participates in membrane-associated mechanisms promoting growth during drought in Arabidopsis thaliana.   DOI:  10.1073/pnas.1510140112 ;  PMID:  26240315
• Jasmonic acid-inducible TSA1 facilitates ER body formation.   DOI:  10.1111/tpj.14112 ;  PMID:  30267434
• A Family of NAI2-Interacting Proteins in the Biogenesis of the ER Body and Related Structures.   DOI:  10.1104/pp.18.01500 ;  PMID:  30770459
• Biogenesis of leaf endoplasmic reticulum body is regulated by both jasmonate-dependent and independent pathways.   DOI:  10.1080/15592324.2019.1622982 ;  PMID:  31132914
• NAI2 and TSA1 Drive Differentiation of Constitutive and Inducible ER Body Formation in Brassicaceae.   DOI:  10.1093/pcp/pcz236 ;  PMID:  31879762
• The Arabidopsis transcription factor NAI1 activates the NAI2 promoter by binding to the G-box motifs.   DOI:  10.1080/15592324.2020.1846928 ;  PMID:  33315514
• An Arabidopsis protein with a novel calcium-binding repeat sequence interacts with TONSOKU/MGOUN3/BRUSHY1 involved in meristem maintenance.   DOI:  10.1093/pcp/pci155 ;  PMID:  15964904
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.   DOI:  10.1105/tpc.107.050989 ;  PMID:  17951448
• Comparative proteomic analysis of NaCl stress-responsive proteins in Arabidopsis roots.   DOI:  10.1093/jxb/erm207 ;  PMID:  17916636
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.   DOI:  10.1105/tpc.107.050989 ;  PMID:  17951448
• Comparative proteomic analysis of NaCl stress-responsive proteins in Arabidopsis roots.   DOI:  10.1093/jxb/erm207 ;  PMID:  17916636

Sequences: